Patatin-Like phospholipase Domain Containing 8 Proteine (PNPLA8)

PNPLA8 encodes a member of the patatin-like phospholipase domain containing protein family. Zusätzlich bieten wir Ihnen Patatin-Like phospholipase Domain Containing 8 Antikörper (38) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PNPLA8 50640 Q9NP80
PNPLA8 67452 Q8K1N1
Ratte PNPLA8 PNPLA8 314075  
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Top Patatin-Like phospholipase Domain Containing 8 Proteine auf antikoerper-online.de

Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 60 bis 65 Tage
$8,623.45
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 60 bis 65 Tage
$6,052.17
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Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$333.33
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PNPLA8 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Patatin-Like phospholipase Domain Containing 8 (PNPLA8) Interaktionspartnern

Human Patatin-Like phospholipase Domain Containing 8 (PNPLA8) Interaktionspartner

  1. iPLA2gamma plays an important role in in vivo Thromboxane A2 production accompanied by thrombus formation.

  2. iPLA2gamma plays a cardioprotective role during the acute stage of Chagas' disease.

  3. Thus, complement-mediated activation of iPLA(2)gamma is mediated via ERK (zeige EPHB2 Proteine) and p38 (zeige CRK Proteine) pathways, and phosphorylation of Ser (zeige SIGLEC1 Proteine)-511 and/or Ser (zeige SIGLEC1 Proteine)-515 plays a key role in the catalytic activity and signaling of iPLA(2)gamma.

  4. These results suggest distinct roles for iPLA2beta (zeige PLA2G6 Proteine) and iPLA2gamma in cellular homeostasis and signaling, a functional link between peroxisomal AA release and eicosanoid generation, and a potential contribution of iPLA2gamma to tumorigenesis.

  5. iPLA2 (zeige PLA2G6 Proteine) activation is not sufficient for SOCE activation. iPLA2 (zeige PLA2G6 Proteine) may regulate basal phosphoinositide metabolism

Mouse (Murine) Patatin-Like phospholipase Domain Containing 8 (PNPLA8) Interaktionspartner

  1. these results demonstrate the integrated roles of Cardiolipin and iPLA2gamma in lipid second-messenger production and mitochondrial bioenergetics during oxidative stress.

  2. Because mitochondrial membrane depolarization and calcium are known to activate iPLA2gamma, these results are consistent with salvage of myocardium after Ischemia/Reperfusion by iPLA2gamma loss of function through decreasing mPTP (zeige PTPN2 Proteine) opening, diminishing production of proinflammatory oxidized fatty acids

  3. UCP2 (zeige UCP2 Proteine), functional due to fatty acids released by redox-activated mt-iPLA2gamma, suppresses mitochondrial superoxide production by its uncoupling action.

  4. Mitochondrial dysfunction and reduced prostaglandin synthesis in skeletal muscle of Group VIB (zeige SEMA6B Proteine) Ca2 (zeige CA2 Proteine)+-independent phospholipase A2gamma-deficient mice

  5. iPLA(2)beta (zeige PLA2G6 Proteine) and iPLA(2 (zeige PLA2G6 Proteine))gamma are required for the adipogenic program that drives resting 3T3-L1 cells into adipocytes after hormone stimulation

  6. iPLA2 (zeige PLA2G6 Proteine) signaling plays an important role in glucose-stimulated insulin (zeige INS Proteine) secretion under physiological conditions

  7. iPLA(2 (zeige PLA2G6 Proteine))gamma is essential for maintaining efficient bioenergetic mitochondrial function through tailoring mitochondrial membrane lipid metabolism and composition

  8. the obligatory role of iPLA(2 (zeige PLA2G6 Proteine))gamma in neuronal mitochondrial lipid metabolism and membrane structure demonstrating that iPLA(2 (zeige PLA2G6 Proteine))gamma loss of function results in a mitochondrial neurodegenerative disorder

Patatin-Like phospholipase Domain Containing 8 (PNPLA8) Protein Überblick

Protein Überblick

This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit PNPLA8

  • patatin like phospholipase domain containing 8 (PNPLA8)
  • patatin-like phospholipase domain containing 8 (Pnpla8)
  • 1200006O19Rik Protein
  • AI467579 Protein
  • iPLA2 Protein
  • Ipla2(gamma) Protein
  • IPLA2-2 Protein
  • IPLA2G Protein
  • iPLA2gamma Protein
  • RGD1311444 Protein

Bezeichner auf Proteinebene für PNPLA8

PNPLA-gamma , calcium-independent phospholipase A2-gamma , iPLA2 gamma , iPLA2-gamma , intracellular membrane-associated calcium-independent phospholipase A2 gamma , membrane-associated calcium-independent phospholipase A2 gamma , patatin-like phospholipase domain-containing protein 8 , group VIB calcium-independent phospholipase A2

GENE ID SPEZIES
50640 Homo sapiens
67452 Mus musculus
314075 Rattus norvegicus
100328577 Oryctolagus cuniculus
Ausgewählte Anbieter für Patatin-Like phospholipase Domain Containing 8 Proteine (PNPLA8)
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