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The protein encoded by PRPF4 is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. Zusätzlich bieten wir Ihnen PRP4 Pre-MRNA Processing Factor 4 Homolog (Yeast) Antikörper (19) und viele weitere Produktgruppen zu diesem Protein an.
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The p.R192H variant of PRPF4 represents a functional null allele which compromises the function of the tri (zeige VANGL2 Proteine)-snRNP (zeige LSM2 Proteine), reinforcing the notion that this spliceosomal particle is of crucial importance in the physiology of the retina.
PRPF4 missense mutations is associated with autosomal dominant retinitis pigmentosa.
the requirement of enzymatic activity of PRP4 (zeige PRPF4B Proteine) in regulating cancer cell growth and identified an array of potential novel substrates through orthogonal proteomics approaches
interaction between Hprp3p (zeige PRPF3 Proteine) and Hprp4p
PRP4 (zeige PRPF4B Proteine) is a spindle assembly checkpoint protein required for MPS1 (zeige IDUA Proteine), MAD1 (zeige MXD1 Proteine), and MAD2 (zeige MAD2L1 Proteine) localization to the kinetochores.
PRP-4 (zeige PRPF4B Proteine) belongs to the serine/threonine protein kinase (zeige PRKACG Proteine) family, plays a role in pre-mRNA splicing and cell mitosis, and interacts with CLK1 (zeige CDK11B Proteine)
The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Two transcript variants encoding different isoforms have been found for this gene.
U4/U6 small nuclear ribonucleoprotein Prp4
, PRP4 pre-mRNA processing factor 4 homolog (yeast)
, WD40 repeat-containing protein
, pre-mRNA processing factor 4
, U4/U6 small nuclear ribonucleoprotein Prp4-like
, PRP4 homolog
, PRP4/STK/WD splicing factor
, U4/U6 snRNP 60 kDa protein
, WD splicing factor Prp4