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PRKC, Apoptosis, WT1, Regulator Proteine (PAWR)

The tumor suppressor WT1 represses and activates transcription. Zusätzlich bieten wir Ihnen PAWR Antikörper (64) und PAWR Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PAWR 5074 Q96IZ0
Ratte PAWR PAWR 64513 Q62627
PAWR 114774 Q925B0
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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PAWR Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu PRKC, Apoptosis, WT1, Regulator (PAWR) Interaktionspartnern

Human PRKC, Apoptosis, WT1, Regulator (PAWR) Interaktionspartner

  1. Prostate apoptosis response 4 (PAR4) expression modulates WNT (zeige WNT2 Proteine) signaling pathways in MCF7 breast cancer cells: A possible mechanism underlying PAR4-mediated docetaxel chemosensitivity.

  2. Decreased PAR4 expression in breast cancer is associated with shorter survival. PAR4 suppresses growth and invasiveness of breast cancer cells.

  3. Authors determined that PAR-4 induces cell apoptosis in response to stimuli, in vitro, but is also involved in the relocation of GRP78 (zeige HSPA5 Proteine) from endoplasmic reticulum to the cell surface of ovarian cancer cell line.

  4. These results suggest that Porphyromonas gingivalis activates PAR4 signaling pathways, leading proMMP9 over-expression and cellular invasion in oral squamous cell carcinoma cells.

  5. PAR1 (zeige MARK2 Proteine)-platelet releasate enhances vasculogenesis more potently than PAR4-platelet releasate, and the enhancements require a cooperation of multiple platelet-derived angiogenic regulators.

  6. A novel long non-coding RNA T-ALL-R-LncR1 knockdown and Par-4 cooperate to induce cellular apoptosis in T-cell acute lymphoblastic leukemia cells.

  7. Data indicate that PAR1 (zeige MARK2 Proteine) and PAR4 activate common promigratory signalling pathways in Hep3B liver carcinoma cells including activation of the receptor tyrosine kinases Met and PDGFR (zeige PDGFRB Proteine), the formation of ROS (zeige ROS1 Proteine) and the inactivation of PTP1B (zeige PTPN1 Proteine).

  8. a Par-4 mutant that is unable to bind Fbxo45 (zeige FBXO45 Proteine) is stabilized and further enhances staurosporine-induced apoptosis.

  9. C-terminus of the rat homologue of Par-4 was crystallized and a 3.7 A resolution X-ray diffraction data set was collected

  10. These results indicate that the expression of PAR1 (zeige MARK2 Proteine) and PAR2 (zeige F2RL1 Proteine) in esophageal squamous cell carcinoma is increased but PAR4 is decreased.

Mouse (Murine) PRKC, Apoptosis, WT1, Regulator (PAWR) Interaktionspartner

  1. Par4 (zeige F2RL3 Proteine), CEBPB (zeige CEBPB Proteine) and FAK (zeige PTK2 Proteine) form a senescence signaling pathway, playing roles in modulating cell survival, growth, apoptosis, EMT (zeige ITK Proteine) and self-renewal

  2. a novel mechanism of apoptosis induction by PAR-4 (zeige F2RL3 Proteine)/ceramide-enriched exosomes, which may critically contribute to Alzheimer disease.

  3. extracellular Par-4 (zeige F2RL3 Proteine)/SAC (zeige ADCY10 Proteine) is systemically functional in inhibition of tumor growth and metastasis progression.

  4. loss of PAR4 (zeige F2RL3 Proteine) leads to a reduction in the ability of tumour necrosis factor-alpha (zeige TNF Proteine) to induce apoptosis by increased activation of NF-kappaB (zeige NFKB1 Proteine)

  5. Antisense knockdown of PAR-4 (zeige F2RL3 Proteine) or inhibition of ceramide biosynthesis reduced stem cell apoptosis; PAR-4 (zeige F2RL3 Proteine) overexpression and treatment with ceramide analogs elevated apoptosis.

  6. AATF (zeige AATF Proteine) is an endogenous antagonist of Par-4 (zeige F2RL3 Proteine) activity and an effective inhibitor of aberrant amyloid beta 1-42 production and secretion under apoptotic conditions.

  7. Par-4 is directly involved in regulating choline uptake by interacting with CHT1 and by reducing its incorporation on the cell surface

  8. the mechanism for Ras-mediated down-regulation of Par-4 (zeige F2RL3 Proteine) is by promoter methylation

  9. direct physical association with ceramide and PAR-4 (zeige F2RL3 Proteine) regulates the activity of PKCzeta (zeige PRKCZ Proteine)

  10. Par-4 (zeige F2RL3 Proteine) is identified as a regulatory component in dopamine signaling

PAWR Protein Überblick

Protein Überblick

The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.

Genbezeichner und Symbole assoziert mit PAWR

  • PRKC, apoptosis, WT1, regulator (PAWR)
  • PRKC, apoptosis, WT1, regulator (pawr)
  • PRKC, apoptosis, WT1, regulator (Pawr)
  • 2310001G03Rik Protein
  • MGC81382 Protein
  • Par-4 Protein
  • Par4 Protein
  • PAWR Protein
  • pawrl Protein
  • zgc:103513 Protein

Bezeichner auf Proteinebene für PAWR

PRKC, apoptosis, WT1, regulator , PAR-4 , PRKC apoptosis WT1 regulator protein , PRKC, apoptosis, WT1, regulator like , WT1-interacting protein , prostate apoptosis response 4 protein , prostate apoptosis response protein 4 , prostate apoptosis response protein PAR-4 , prostate apoptosis response-4 , transcriptional repressor PAR4 , Prostate apoptosis response protein 4 , par-4 induced by effectors of apoptosis , transcriptional repressor Par-4-like protein PAWR

GENE ID SPEZIES
417870 Gallus gallus
447443 Xenopus laevis
449994 Danio rerio
452094 Pan troglodytes
532789 Bos taurus
695617 Macaca mulatta
5074 Homo sapiens
64513 Rattus norvegicus
114774 Mus musculus
611487 Canis lupus familiaris
Ausgewählte Anbieter für PAWR Proteine (PAWR)
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