anti-PR Domain Containing 2, with ZNF Domain (PRDM2) Antikörper

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. Zusätzlich bieten wir Ihnen PRDM2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PRDM2 7799 Q13029
PRDM2 110593  
PRDM2 313678 Q63755
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Top anti-PRDM2 Antikörper auf antikoerper-online.de

Showing 10 out of 72 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, IHC (p), IP, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert ChIP, WB Western blot analysis of anti-PRDM2 Mab (ABIN387783) in lysate from transformed cells. Lane A: mock plasmid, Lane B: PRDM2[1-347]-encoding plasmid. PRDM2[1-347] (arrow) was detected using purified Mab. Secondary HRP-anti-mouse was used for signal visualization with chemiluminescence. (A) Soluble chromatin was prepared from MCF7 cells not treated or treated with E2 for 45 min. Immunoprecipitation was performed with antibodies against RIZ1. DNA extractions were amplified by using primer sets that cover the pS2 gene promoter region or the GAPDH gene promoter. (B) Time course analysis of RIZ1 binding to the pS2 gene promoter. MCF7 cells treated with E2 for different periods of time, as indicated at the top of each lane, were processed for ChIP analysis. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p) A) Rat B50 brain tumor cell extracts were immunoprecipitated with RIZ antibody (ABIN388010) or preimmune (ref.9). B)Immunohistochemical analysis of RIZ1 in adenovirus-transduced tumor cells. Established HCT116 xenograft tumors at day 2 after infection of AdRIZ1, Adnull, or buffer alone were processed for RIZ1 in situ detection (TUNEL) analysis (ref.10). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000;  TMB staining; Read the data in Microplate Reader by 450nm Formalin-fixed and paraffin-embedded rat brain labeled with Anti-KMT8/Riz1/Riz2 Polyclonal Antibody, Unconjugated (ABIN763001) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C.DAPI was used to stain the cell nuclei 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Human Kaninchen Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$163.90
Details
Human Kaninchen HRP IHC (p), WB   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen Alexa Fluor 647 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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PRDM2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-PRDM2 Antikörper

  1. Human Monoclonal PRDM2 Primary Antibody für ChIP, WB - ABIN387783 : Lakshmikuttyamma, Takahashi, Pastural, Torlakovic, Amin, Garcia-Manero, Voralia, Czader, DeCoteau, Geyer: RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression. in Journal of hematology & oncology 2009 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen PRDM2 Interaktionspartner

Human PR Domain Containing 2, with ZNF Domain (PRDM2) Interaktionspartner

  1. Promoter region methylation of RIZ1 may play an important role in the epigenetic silencing of RIZ1 expression in pituitary adenomas, which may translate into important diagnostic and therapeutic applications

  2. RIZ1 expression is negatively correlated with glioma differentiation and can serve as a predictor of glioma prognosis and thus could be a potential therapeutic target for patients with gliomas.

  3. Loss of RIZ1 expression due to methylation is associated with Renal Cell Carcinoma (zeige MOK Antikörper).

  4. PRDM2 downregulation may play a role in dopamine-agonist resistance and tumor recurrence in prolactinomas.

  5. Results suggest that high expression of SMYD3 (zeige SMYD3 Antikörper) is related to the occurrence of esophageal squamous cell carcinoma. Also, its suppression promoted the expression of RIZ1 suggesting a signal transduction pathway between SMYD3 (zeige SMYD3 Antikörper) and RIZ1.

  6. PRDM2, PRDM5 (zeige PRDM5 Antikörper), PRDM16 (zeige PRDM16 Antikörper) promoters are methylated and their expression is suppressed in lung cancer cells.

  7. The development and progression of esophageal squamous cell carcinoma are related to the inactivation of RIZ1.

  8. RIZ1 expression is significantly downregulated as the formation of meningiomas progressed, and suggest that RIZ1 may represent a promising candidate tumor suppressor gene that contributes to malignant meningiomas.

  9. Reduction of RIZ1 expression aggravates the progression of liver fluke-related cholangiocarcinoma

  10. Aberrant methylation and decreased expression of the RIZ1 gene are frequent in adult acute lymphoblastic leukemia of T-cell phenotype

Mouse (Murine) PR Domain Containing 2, with ZNF Domain (PRDM2) Interaktionspartner

  1. RIZ1 is an important regulator of both Akt3 (zeige AKT3 Antikörper) transcription and AKT (zeige AKT1 Antikörper) phosphorylation and suggest a role for RIZ1 in HF-induced obesity and the AKT (zeige AKT1 Antikörper) pathway

  2. RIZ1 might participate osteoclast formation through the regulation of NFATc1 (zeige NFATC1 Antikörper) expression.

  3. Data suggest that the histone methyltransferase RIZ1 is required for estrogen response in female reproductive tissues and that estrogen-bound estrogen receptors may turn a transcriptional repressor into a coactivator.

PRDM2 Antigen-Profil

Protein Überblick

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit PRDM2

  • PR domain containing 2, with ZNF domain S homeolog (prdm2.S) Antikörper
  • PR domain containing 2, with ZNF domain b (prdm2b) Antikörper
  • PR domain containing 2, with ZNF domain (prdm2) Antikörper
  • PR domain zinc finger protein 2 (LOC100350859) Antikörper
  • PR/SET domain 2 (PRDM2) Antikörper
  • PR domain containing 2, with ZNF domain (Prdm2) Antikörper
  • PR/SET domain 2 (Prdm2) Antikörper
  • 4833427P12Rik Antikörper
  • E330024L24Rik Antikörper
  • Gm1033 Antikörper
  • Gm19732 Antikörper
  • HUMHOXY1 Antikörper
  • KMT8 Antikörper
  • MGC114763 Antikörper
  • MTB-ZF Antikörper
  • PRDM2 Antikörper
  • Riz Antikörper
  • Riz1 Antikörper
  • RIZ2 Antikörper
  • Znfpr1c1 Antikörper

Bezeichner auf Proteinebene für PRDM2

PR domain containing 2, with ZNF domain , retinoblastoma protein-binding zinc finger protein-like , PR domain zinc finger protein 2-like , GATA-3 binding protein G3B , GATA-3-binding protein G3B , MTE-binding protein , PR domain zinc finger protein 2 , PR domain-containing protein 2 , lysine N-methyltransferase 8 , retinoblastoma protein-binding zinc finger protein , retinoblastoma protein-interacting zinc finger protein , zinc finger protein RIZ , zinc-finger DNA-binding protein , retinoblastoma interacting zinc finger protein

GENE ID SPEZIES
494709 Xenopus laevis
797296 Danio rerio
100170624 Xenopus (Silurana) tropicalis
100350859 Oryctolagus cuniculus
100385110 Callithrix jacchus
100436958 Pongo abelii
100010516 Monodelphis domestica
469125 Pan troglodytes
100481446 Ailuropoda melanoleuca
100582767 Nomascus leucogenys
7799 Homo sapiens
110593 Mus musculus
313678 Rattus norvegicus
419478 Gallus gallus
100688431 Canis lupus familiaris
789222 Bos taurus
Ausgewählte Anbieter für anti-PRDM2 (PRDM2) Antikörper
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