anti-PHD Finger Protein 6 (PHF6) Antikörper

PHF6 is a member of the plant homeodomain (PHD)-like finger (PHF) family. Zusätzlich bieten wir Ihnen PHF6 Proteine (7) und PHF6 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PHF6 84295 Q8IWS0
PHF6 70998 Q9D4J7
PHF6 100359714  
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Top anti-PHF6 Antikörper auf antikoerper-online.de

Showing 10 out of 42 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PHF6 Antibody Titration: </b>5.0ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PHF6 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PHF6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Human brain 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Western Blot: PHF6 Antibody [ABIN2611772] - Image from a customer review testing on 293T cells. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: PHF6 Antibody [NBP1-88646] - Staining of human colon shows strong nuclear positivity in glandular cells. Immunocytochemistry/Immunofluorescence: PHF6 Antibody [NBP1-88646] - Staining of human cell line U-251MG shows positivity in nucleus & nucleoli. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IP, IHC, WB Immunohistochemistry-Paraffin: PHF6 Antibody [ABIN2611761] - Detection of Mouse PHF6 by Immunohistochemistry. Sample: FFPE section of mouse renal cell carcinoma. Antibody: Affinity purified rabbit anti-PHF6 used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Hund Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$343.75
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$433.13
Details

PHF6 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
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,
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Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-PHF6 Antikörper

  1. Human Polyclonal PHF6 Primary Antibody für ICC, IF - ABIN261177 : Meacham, Lawton, Soto-Feliciano, Pritchard, Joughin, Ehrenberger, Fenouille, Zuber, Williams, Young, Hemann: A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth. in Genes & development 2015 (PubMed)

  2. Human Polyclonal PHF6 Primary Antibody für ICC, IF - ABIN4345225 : Pontén, Jirström, Uhlen: The Human Protein Atlas--a tool for pathology. in The Journal of pathology 2008 (PubMed)

Weitere Antikörper gegen PHF6 Interaktionspartner

Human PHD Finger Protein 6 (PHF6) Interaktionspartner

  1. PHF6 localizes to the sub-nucleolar fibrillar center where it binds to rDNA-coding sequences. PHF6 mediates the overall levels of ribosome biogenesis within a cell.

  2. Our results suggest that PHF6 may function as an oncogenic factor in several types of cancer. We also hypothesize that PHF6 may also play its role in a tissue-specific manner. Our findings suggest further investigations regarding the exact role of PHF6 in tumor types.

  3. Female phenotypes of Borjeson-Forssman-Lehmann syndrome patients with PHF6 mutations

  4. Our RBBP4 (zeige RBBP4 Antikörper)-PHF6 complex structure provides insights into the molecular basis of PHF6-NuRD complex interaction and implicates a role for PHF6 in chromatin structure modulation and gene regulation.

  5. Phf6 is a "lineage-specific" cancer gene that plays opposing roles in developmentally distinct hematopoietic malignancies.

  6. The PHF6 tumor suppressor gene was targeted in acute lymphoblastic leukemia by microRNA-128-3p.

  7. Our report confirms that PHF6 loss in females results in a recognizable phenotype overlapping with Coffin-Siris syndrome and distinct from Borjeson-Forssman-Lehmann syndrome.

  8. Recurrent microdeletion was detected in Xq26.3, causing loss of PHF6 expression, a potential tumor suppressor gene, and the miR (zeige MLXIP Antikörper)-424, which is involved in the development of acute myeloid leukemia (zeige BCL11A Antikörper).

  9. The findings show that de novo mutations in PHF6 in females result in a recognisable phenotype which overlap with Borjeson-Forssman-Lehmann syndrome but also has additional distinct features, thus adding a new facet to this disorder.

  10. these data support the hypothesis that PHF6 may function as a transcriptional repressor using its ePHD domains binding to the promoter region of its repressed gene

Mouse (Murine) PHD Finger Protein 6 (PHF6) Interaktionspartner

  1. active maintenance of a precise chromatin landscape is essential for sustaining proper leukemia cell identity and that loss of a single factor (PHF6) can cause focal changes in chromatin accessibility and nucleosome positioning that render cells susceptible to lineage transition

  2. These results place miR (zeige MLXIP Antikörper)-128 upstream of PHF6 in a pathway vital for cortical lamination as well as for the development of neuronal morphology and intrinsic excitability.

  3. As part of a cell-intrinsic transcriptional pathway, PHF6 regulates neuronal migration in the brain.

  4. Strongest Phf6 gene expression and nuclear localisation of Phf6 protein were observed in the developing central nervous system, the anterior pituitary gland, the primordia of facial structures and the limb buds.

PHF6 Antigen-Profil

Protein Überblick

This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms.

Genbezeichner und Symbole assoziert mit PHF6

  • PHD finger protein 6 (phf6) Antikörper
  • PHD finger protein 6 (PHF6) Antikörper
  • PHD finger protein 6 (LOC100225613) Antikörper
  • PHD finger protein 6 (LOC100346149) Antikörper
  • PHD finger protein 6 (Phf6) Antikörper
  • 2700007B13Rik Antikörper
  • 4931428F02Rik Antikörper
  • BFLS Antikörper
  • BORJ Antikörper
  • CENP-31 Antikörper
  • mKIAA1823 Antikörper
  • wu:fa22g03 Antikörper
  • zgc:55403 Antikörper

Bezeichner auf Proteinebene für PHF6

PHD finger protein 6 , PHD-like zinc finger protein , centromere protein 31

GENE ID SPEZIES
327070 Danio rerio
495066 Xenopus laevis
707390 Macaca mulatta
779543 Xenopus (Silurana) tropicalis
100151997 Sus scrofa
100225613 Taeniopygia guttata
100346149 Oryctolagus cuniculus
100379647 Monodelphis domestica
735789 Pan troglodytes
100054177 Equus caballus
84295 Homo sapiens
422235 Gallus gallus
612921 Canis lupus familiaris
518186 Bos taurus
70998 Mus musculus
100359714 Rattus norvegicus
100174671 Pongo abelii
Ausgewählte Anbieter für anti-PHF6 (PHF6) Antikörper
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