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Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Zusätzlich bieten wir Ihnen PHD Finger Protein 17 Antikörper (42) und PHD Finger Protein 17 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
The ciliary protein nephrocystin-4 (zeige NPHP4 ELISA Kits) translocates the canonical Wnt (zeige WNT2 ELISA Kits) regulator Jade-1 to the nucleus to negatively regulate beta-catenin (zeige CTNNB1 ELISA Kits) signaling.
identification of SNPs within the IQCJ, NXPH1 (zeige NXPH1 ELISA Kits), PHF17 and MYB (zeige MYB ELISA Kits) genes partly explaining the large interindividual variability observed in plasma triglyceride levels in response to an n-3 fatty acid supplementation
A genome-wide association study (GWAS) identified loci associated with the plasma triglyceride (TG) response to omega-3 fatty acid (FA) supplementation in IQCJ, NXPH1 (zeige NXPH1 ELISA Kits), PHF17 and MYB (zeige MYB ELISA Kits).
JADE1 expression has a role in colon cancers, renal carcinomas, and in acute kidney injuries and regeneration. (Review)
Interactome analyses revealed that the Jade-1S mutant unable to be phosphorylated by CK1alpha (zeige CSNK1A1 ELISA Kits) has an increased binding affinity to proteins involved in chromatin remodelling, histone deacetylation, transcriptional repression, and ribosome biogenesis.
Casein kinase 1 (zeige CSNK1A1 ELISA Kits) alpha specifically phosphorylates Jade-1 at an unprimed SLS (zeige ALDH3A2 ELISA Kits) phosphorylation site.
Increase in the number of cells with cytoplasmic JADE1S correlated with activation of tubular cell proliferation and inversely correlated with the number of cells with nuclear JADE1S, supporting role of HBO1 (zeige MYST2 ELISA Kits)-JADE1 shuttling during organ regeneration.
lncRNA-JADE is a key functional link that connects the DDR to histone H4 acetylation, and that dysregulation of lncRNA-JADE may contribute to breast tumorigenesis.
Reduced Jade-1 expression is associated with clear-cell renal cell carcinomas.
RCC (zeige XRCC1 ELISA Kits) with a low expression of Jade-1 is associated with a poor outcome and decreased survival
Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor (By similarity).
PHD finger protein 17
, protein Jade-1-like
, protein Jade-1
, PHD protein Jade-1
, gene for apoptosis and differentiation in epithelia
, Jade1 PHD finger protein