PGD Synthetase Proteine (PGDS)

The protein encoded by PGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). Zusätzlich bieten wir Ihnen PGD Synthetase Kits (20) und PGD Synthetase Antikörper (12) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Maus PGDS PGDS 19215 O09114
Ratte PGDS PGDS 25526 P22057
PGDS 5730 P41222
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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PGDS Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human

Weitere Proteine zu PGD Synthetase (PGDS) Interaktionspartnern

Mouse (Murine) PGD Synthetase (PGDS) Interaktionspartner

  1. Exposure of macrophages to cyclooxygenase (COX-2) inhibitors RhoA (zeige RHOA Proteine) and LA-4 cells to antagonists of prostaglandin E2 (PGE2) receptor , PGD2 (zeige PTGDS Proteine) receptors or the hepatocyte growth factor (HGF (zeige HGF Proteine)) receptor c-Met (PHA (zeige LBR Proteine)-665752), reversed EMT (zeige ITK Proteine) inhibition by the conditioned medium

  2. Ptgds (zeige PTGDS Proteine) is targeted and repressed by the CUL4B (zeige CUL4B Proteine)/PRC2 complex.

  3. Thermodynamic and nuclear magnetic resonance analyses demonstrated that L-PGDS binds to nicotinamide coenzymes, including NADPH, NADP(+), and NADH.

  4. Prostaglandin D2 synthase is a novel MR target (zeige PTGDS Proteine) gene in adipocytes.

  5. When prostaglandin D2 synthase (zeige PTGDS Proteine) is upregulated it participates in the regulation of peripheral nervous system myelination.

  6. expression of L-PGDS (zeige PTGDS Proteine) in mouse lungs decreased neutrophilic infiltration, ameliorating lung inflammation in mice.

  7. Silencing of PTGDS (zeige PTGDS Proteine) also alleviated H-rev107 (zeige HRASLS Proteine)-mediated suppression of cell migration and invasion

  8. In this report, we show for the first time that alteration of the P (zeige PTGDS Proteine)TGDS-governed PGD2 pathway disturbs testicular migration in mice.

  9. Data indicate a PLA2G3 (zeige PLA2G3 Proteine)-lipocalin (zeige APOD Proteine)-type PGD2 synthase (L-PGDS)-PGD2 (zeige PTGDS Proteine) receptor DP1 (zeige PTGDR Proteine) loop that drives mast cell maturation.

  10. The levels of lipocalin (zeige APOD Proteine)-type prostaglandin D2 synthase (zeige PTGDS Proteine), and its product PGD2 (zeige PTGDS Proteine) each varied significantly among background strains of mice after wounding, and the highest Ptgds (zeige PTGDS Proteine) and PGD2 (zeige PTGDS Proteine) levels were associated with the lowest amount of regeneration.

Human PGD Synthetase (PGDS) Interaktionspartner

  1. Serum levels of beta trace protein and beta 2 microglobulin (zeige B2M Proteine) can be used to predict residual kidney function in hemodialysis patients.

  2. BTP and B2M (zeige B2M Proteine) levels are less affected than serum by amputation, and should be considered for future study of GFR (zeige RAPGEF5 Proteine) estimation

  3. Hematopoietic prostaglandin D synthase (zeige HPGDS Proteine) defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function

  4. levels of L-PGDS (zeige PTGDS Proteine) in cervicovaginal secretions of pregnant women at different stages of parturition correlate with preterm birth.

  5. PTGDS (zeige PTGDS Proteine) mRNA expression was down-regulated in rapid-cycling bipolar disorder patients in a euthymic, depressive, and manic/hypomanic state compared with healthy control subjects.

  6. Expression of MR and prostaglandin D2 synthase (zeige PTGDS Proteine) is strongly correlated in adipose tissues from obese patients.

  7. These data indicate that scalp is spatially programmed via mast cell prostaglandin D-synthase (zeige PTGDS Proteine) distribution in a manner reminiscent of the pattern seen in androgenetic alopecia.

  8. These results suggest that L-PGDS (zeige PTGDS Proteine) acted as a scavenger of biliverdin, which is a molecule not found in normal CSF (zeige CSF2 Proteine).

  9. Lipocalin (zeige APOD Proteine)-type prostaglandin D2 (PGD2) synthase (L-PGDS) interacts intracellularly with the G protein-coupled receptor (zeige ADRA1A Proteine) DP1 (zeige PTGDR Proteine) in an agonist-independent manner.

  10. Among NSTE-ACS (zeige PLA2G15 Proteine) patients, BTP and CysC (zeige CST3 Proteine) were superior to conventional renal parameters for predicting MB, and improved clinical stratification for hemorrhagic risk.

PGD Synthetase (PGDS) Protein Überblick

Protein Überblick

The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.

Genbezeichner und Symbole assoziert mit PGD Synthetase Proteine (PGDS)

  • prostaglandin D2 synthase (brain) (Ptgds)
  • prostaglandin D2 synthase 21kDa (brain) (PTGDS)
  • 21kDa Protein
  • L-PGDS Protein
  • LPGDS Protein
  • PDS Protein
  • PGD2 Protein
  • PGDS Protein
  • PGDS2 Protein
  • PH2DISO Protein
  • Ptgs3 Protein

Bezeichner auf Proteinebene für PGD Synthetase Proteine (PGDS)

PGD2 synthase , glutathione-independent PGD synthase , glutathione-independent PGD synthetase , lipocalin-type prostaglandin-D synthase , prostaglandin D2 synthase (21 kDa, brain) , prostaglandin-D2 synthase , prostaglandin-H2 D-isomerase , PGDS , PGDS2 , Prostaglandin D synthase , beta-trace protein , cerebrin-28 , lipocalin-type prostaglandin D synthase , prostaglandin D synthase

GENE ID SPEZIES
19215 Mus musculus
25526 Rattus norvegicus
5730 Homo sapiens
403740 Canis lupus familiaris
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