anti-P21-Activated Kinase 6 (PAK6) Antikörper

PAK6 encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. Zusätzlich bieten wir Ihnen P21-Activated Kinase 6 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PAK6 56924 Q9NQU5
PAK6 214230 Q3ULB5
PAK6 296078  
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Top anti-P21-Activated Kinase 6 Antikörper auf antikoerper-online.de

Showing 10 out of 166 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Western blot analysis of anti-PAK6 Pab (ABIN392439) in lysates from transiently transfected COS7 cells. Lane 1: negative control, Lane 2: PAK1-expressing cells, Lane 3: PAK2-expressing cells, Lane 4: PAK4-expressing cells, Lane 5: PAK5-expressing cells, and Lane 6: PAK6-expressing cells. PAK6 (arrow) was detected using purified polyclonal antibody. Data is kindly provided by Drs. Z.M. Jaffer and J. Chernoff from the Fox Chase Cancer Center (Philadelphia, PA). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB PAK6 Antibody (Center)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PAK6 antibody detected the PAK6 protein (arrow). PAK6 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PAK6 Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IP, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: PAK6 Antibody [NBP1-76632] - Raji cells with PAK6 antibody at 10 ug/ml. Immunocytochemistry/Immunofluorescence: PAK6 Antibody [NBP1-76632] - Immunofluorescence of PAK6 in Raji cells with PAK6 antibody at 10 ug/mL. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of PAK6 expression in HeLa (A), LOVO (B), mouse brain (C), rat brain (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-PAK6 antibody, IHC(P) IHC(P): Rat Brain Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Hund Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: PAK6 Antibody [NLS6942] - Human Lung, Non-Small Cell Carcinoma. formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Immunohistochemistry-Paraffin: PAK6 Antibody [NLS6942] - Analysis of anti-PAK6 antibody with human brain, neurons and glia at 3.5 ug/ml. 0.05 mL Anmelden zum Anzeigen 10 bis 13 Tage
$447.56
Details
Human Kaninchen Unkonjugiert EIA, IF, IHC (p), WB   0.4 mL Anmelden zum Anzeigen 25 bis 30 Tage
$375.38
Details
Human Kaninchen Unkonjugiert IHC (p) Anti-PAK6 antibody  ABIN1049228 IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Hund Kaninchen Unkonjugiert IHC (p) Anti-PAK6 antibody  ABIN1049227 IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details

PAK6 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-P21-Activated Kinase 6 Antikörper

  1. Human Polyclonal PAK6 Primary Antibody für IHC, ELISA - ABIN1002959 : Jaffer, Chernoff: p21-activated kinases: three more join the Pak. in The international journal of biochemistry & cell biology 2002 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal PAK6 Primary Antibody für ELISA, ICC - ABIN4343485 : Raja, Sahasrabuddhe, Radhakrishnan, Syed, Solanki, Puttamallesh, Balaji, Nanjappa, Datta, Babu, Renuse, Patil, Izumchenko, Prasad, Chang, Rangarajan, Sidransky, Pandey, Gowda, Chatterjee: Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells. in Oncotarget 2016 (PubMed)

  3. Dog (Canine) Polyclonal PAK6 Primary Antibody für IHC (p) - ABIN4343483 : Kwek, Dao, Roy, Hou, Alajajian, Simko, Small, Fong: Diversity of antigen-specific responses induced in vivo with CTLA-4 blockade in prostate cancer patients. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)

Weitere Antikörper gegen P21-Activated Kinase 6 Interaktionspartner

Human P21-Activated Kinase 6 (PAK6) Interaktionspartner

  1. RhoD recruits Pak6 to the plasma membrane to antagonize RhoC (zeige RHOC Antikörper) signaling during cell contraction and blebbing

  2. PAK6 localization to cell-cell adhesions is Cdc42 (zeige CDC42 Antikörper)-dependent

  3. p21-activated kinase 6 (PAK6) as a novel interactor of leucine-rich repeat kinase 2 (LRRK2 (zeige LRRK2 Antikörper)), a kinase involved in Parkinson's disease

  4. PAK6 is directly targeted by miR (zeige MLXIP Antikörper)-328. miR (zeige MLXIP Antikörper)-328 inhibits cell growth and promotes cell apoptosis in prostate cancer cells.

  5. negative correlation between PAK6 and EZH2 (zeige EZH2 Antikörper) expression was observed in hepatoma tissues from HCC (zeige FAM126A Antikörper) patients. These data identified the tumor suppressive role and potential underlying mechanism of PAK6 in hepatocarcinogenesis

  6. the results of the present study suggested that miR (zeige MLXIP Antikörper)-429 inhibits the migration and invasion of colon cancer cells, partly at least, by mediating the expression of PAK6, as well as the activity of cofilin (zeige CFL1 Antikörper) signaling

  7. we report that in colon cancer PAK6 promotes tumor progression and chemoresistance both in vitro and in vivo

  8. PAK6 is specifically required for carcinoma cell-cell dissociation downstream of hepatocyte growth factor (HGF (zeige HGF Antikörper)) for both DU145 prostate cancer and HT29 colon cancer cells.

  9. PAK5 plays an essential role in the initiation and progression of hepatocellular carcinoma.

  10. These results demonstrate that androgen-stimulated PAK6 activation is mediated through a direct interaction between AR and PAK6 and PAK6 activation promotes prostate cancer cells motility and invasion.

Mouse (Murine) P21-Activated Kinase 6 (PAK6) Interaktionspartner

  1. p21-activated kinase 6 (PAK6) as a novel interactor of leucine-rich repeat kinase 2 (LRRK2 (zeige LRRK2 Antikörper)), a kinase involved in Parkinson's disease

  2. data suggest that PAK-6 p21 (zeige D4S234E Antikörper)-activated kinase plays a role in weight gain unrelated to exercise and caloric intake

  3. functional deficits in PAK5 (zeige PAK7 Antikörper), PAK6 and PAK5/PAK6 knockout mice

  4. Our results indicate that Pak5 (zeige PAK7 Antikörper) and Pak6 together are not required for viability, but are required for a normal level of locomotion and activity as well as for learning and memory.

P21-Activated Kinase 6 (PAK6) Antigen-Profil

Protein Überblick

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit PAK6

  • p21 (RAC1) activated kinase 6 (PAK6) Antikörper
  • p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6) Antikörper
  • p21 (RAC1) activated kinase 6 (Pak6) Antikörper
  • p21 protein (Cdc42/Rac)-activated kinase 6b (pak6b) Antikörper
  • p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6) Antikörper
  • 4732456M09 Antikörper
  • PAK5 Antikörper
  • pak6 Antikörper
  • si:ch211-158b22.3 Antikörper

Bezeichner auf Proteinebene für PAK6

p21(CDKN1A)-activated kinase 6 , serine/threonine-protein kinase PAK 6 , PAK-6 , p21-activated kinase 6 , p21 (CDKN1A)-activated kinase 6 , p21 protein (Cdc42/Rac)-activated kinase 6

GENE ID SPEZIES
56924 Homo sapiens
214230 Mus musculus
296078 Rattus norvegicus
567874 Danio rerio
100172971 Pongo abelii
100348921 Oryctolagus cuniculus
428837 Gallus gallus
100071463 Equus caballus
100153981 Sus scrofa
539224 Bos taurus
487490 Canis lupus familiaris
100713585 Cavia porcellus
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