anti-Oxysterol Binding Protein-Like 8 (OSBPL8) Antikörper

OSBPL8 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Zusätzlich bieten wir Ihnen Oxysterol Binding Protein-Like 8 Kits (5) und Oxysterol Binding Protein-Like 8 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
OSBPL8 314824  
OSBPL8 114882 Q9BZF1
OSBPL8 237542  
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Top anti-Oxysterol Binding Protein-Like 8 Antikörper auf antikoerper-online.de

Showing 10 out of 20 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-OSBPL8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 721_B cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-OSBPL8 Antibody Titration: 0.2-1 ug/mlPositive Control: OVCAR-3 cell lysate Host: Rabbit   Target Name: OSBPL8   Sample Tissue: OVCAR-3  Antibody Dilution: 1.0 µg/mL OSBPL8 is strongly supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Immunocytochemistry/Immunofluorescence: ORP8 Antibody [NBP2-19634] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:500 dilution. Western Blot: ORP8 Antibody [NBP2-19634] - Sample (30 ug of whole cell lysate) A: U87-MG 7. 5% SDS PAGE gel, diluted at 1:10000. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Maus Unkonjugiert WB OSBPL8 monoclonal antibody (M02), clone 4H6. Western Blot analysis of OSBPL8 expression in Jurkat. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: ORP8 Antibody [NBP1-92235] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts. Immunocytochemistry/Immunofluorescence: ORP8 Antibody [NBP1-92235] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli, cytoplasm & vesicles. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert WB Western Blot: ORP8 Antibody [NBP1-59815] - HT1080, Antibody Dilution: 1.0 ug/ml OSBPL8 is strongly supported by BioGPS gene expression data to be expressed in Human HT1080 cells. Western Blot: ORP8 Antibody [NBP1-59815] - OVCAR-3 cell lysate, concentration 0.2-1 ug/ml. 100 μL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert IHC, WB Western Blot: ORP8 Antibody [NBP1-59814] - Reccomended Titration: 0.2 - 1 ug/ml ELISA Titer: 1:1562500 Positive Control: 721_B cell lysate OSBPL8 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells Western Blot: ORP8 Antibody [NBP1-59814] - 721_B cell lysate, concentration 0.2-1 ug/ml. 100 μL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details

OSBPL8 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Rat (Rattus)


Human ,
,
,
Mouse (Murine)


Am meisten referenzierte anti-Oxysterol Binding Protein-Like 8 Antikörper

  1. Cow (Bovine) Polyclonal OSBPL8 Primary Antibody für IHC, WB - ABIN2781875 : Yan, Mäyränpää, Wong, Perttilä, Lehto, Jauhiainen, Kovanen, Ehnholm, Brown, Olkkonen: OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages. in The Journal of biological chemistry 2007 (PubMed)

Weitere Antikörper gegen Oxysterol Binding Protein-Like 8 Interaktionspartner

Human Oxysterol Binding Protein-Like 8 (OSBPL8) Interaktionspartner

  1. mammalian ORP5 (zeige OSBPL5 Antikörper) and ORP8 proteins localize to ER-mitochondrial MCS (zeige SMCP Antikörper), in addition to ER-PM contact sites.

  2. the present study suggests that ORP8 may mediate the cytotoxicity of 25-hydroxycholesterol.

  3. ORP5 (zeige OSBPL5 Antikörper) and ORP8 could mediate PI4P/phosphatidylserine (PS) countertransport between the endoplasmic reticulum (ER) and the plasma membrane (PM), thus delivering PI4P to the ER-localized PI4P phosphatase Sac1 (zeige SACM1L Antikörper) for degradation and PS from the ER to the PM.

  4. role of ORP8 in Fas (zeige FAS Antikörper) translocation to the plasma membrane and its down-regulation by miR (zeige MLXIP Antikörper)-143 offer a putative mechanistic explanation for HCC (zeige FAM126A Antikörper) resistance to apoptosis

  5. Data indicate that miR (zeige MLXIP Antikörper)-143 impairs insulin (zeige INS Antikörper) action via downregulation of oxysterol-binding protein-related protein 8 (ORP8).

  6. ORP8 overexpression resulted in reduced expression of the aP2 (zeige GTF3A Antikörper) mRNA, while down-regulation of adiponectin (zeige ADIPOQ Antikörper) and aP2 (zeige GTF3A Antikörper) was observed in ORP11 (zeige OSBPL11 Antikörper) silenced cells. ORP8 overexpression or silencing of ORP11 (zeige OSBPL11 Antikörper) markedly decreased cellular triglyceride storage.

  7. results reveal that ORP8 has the capacity to modulate lipid homeostasis and SREBP activity, probably through an indirect mechanism, and provide clues of an entirely new mode of ORP action

  8. Data identify ORP8 as a negative regulator of ABCA1 (zeige ABCA1 Antikörper) expression and macrophage cholesterol efflux. ORP8 may, thus, modulate the development of atherosclerosis.

Mouse (Murine) Oxysterol Binding Protein-Like 8 (OSBPL8) Interaktionspartner

  1. Orp8 deficiency in bone marrow-derived cells reduces atherosclerotic lesion progression in LDL receptor (zeige LDLR Antikörper) knockout mice.

  2. Osbpl8 deficiency in mouse causes an elevation of high-density lipoproteins and gender-specific alterations of lipid metabolism.

  3. aspects of ORP8 function in macrophages not directly involving lipid metabolism, but rather associated with nuclear functions, microtubule organization, and migration capacity

Oxysterol Binding Protein-Like 8 (OSBPL8) Antigen-Profil

Protein Überblick

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit OSBPL8

  • oxysterol binding protein-like 8 (Osbpl8) Antikörper
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Bezeichner auf Proteinebene für OSBPL8

oxysterol-binding protein-related protein 8 , oxysterol binding protein-like 8 , oxysterol-binding protein-like protein 8 , oxysterol-binding protein-related protein 8-like , ORP-8 , OSBP-related protein 8

GENE ID SPEZIES
314824 Rattus norvegicus
417866 Gallus gallus
446929 Xenopus laevis
452085 Pan troglodytes
693338 Macaca mulatta
100018363 Monodelphis domestica
100059086 Equus caballus
100145444 Xenopus (Silurana) tropicalis
100172591 Pongo abelii
100175952 Ciona intestinalis
100218984 Taeniopygia guttata
100356792 Oryctolagus cuniculus
100484438 Ailuropoda melanoleuca
100525288 Sus scrofa
100566303 Anolis carolinensis
100595122 Nomascus leucogenys
100409878 Callithrix jacchus
114882 Homo sapiens
475408 Canis lupus familiaris
533350 Bos taurus
237542 Mus musculus
Ausgewählte Anbieter für anti-Oxysterol Binding Protein-Like 8 (OSBPL8) Antikörper
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