anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) Antikörper

OLR1 encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. Zusätzlich bieten wir Ihnen OLR1 Kits (78) und OLR1 Proteine (27) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
OLR1 4973 P78380
OLR1 108078 Q9EQ09
OLR1 140914 O70156
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Top anti-OLR1 Antikörper auf antikoerper-online.de

Showing 10 out of 243 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat aorta labeled with Anti-LOX-1 Polyclonal Antibody, Unconjugated (ABIN676988) followed by conjugation to the secondary antibody and DAB staining Human A549 cells probed with Rabbit Anti-LOX1 Polyclonal Antibody, Unconjugated . 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$307.45
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of OLR1 Antibody (Center) (ABIN652795) in HL-60 cell line lysates (35 µg/lane).OLR1 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of OLR1 (arrow) using rabbit polyclonal OLR1 Antibody (Center) (ABIN652795). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the OLR1 gene (Lane 2) . 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Maus Ratte PE FACS Detection of LOX-1/OLR1 in RAW 264.7 Mouse Cell Line by Flow Cytometry. RAW 264.7 mouse monocyte/macrophage cell line was stained with Rat Anti-Mouse LOX-1/OLR1 PE-conjugated Monoclonal Antibody. Detection of LOX-1/OLR1 in RAW 264.7 Mouse Cell Line by Flow Cytometry. RAW 264.7 mouse monocyte/macrophage cell line was stained with Rat Anti-Mouse LOX-1/OLR1 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$299.25
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged OLR1 is approximately 3 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Maus Unkonjugiert Func, IF   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$599.50
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: LOX-1/OLR1 Antibody [NBP2-44314] - Analysis of Human Liver lysate (35ug protein in RIPA buffer). 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Human Kaninchen Unkonjugiert WB Anti- LOX1 antibody, Western blotting All lanes: Anti LOX1  at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 2: HELA Whole Cell Lysate at 40ug Lane 3: K562 Whole Cell Lysate at 40ug Lane 4: HELA Whole Cell Lysate at 40ug Lane 5: RAJI Whole Cell Lysate at 40ug Predicted bind size: 31KD Observed bind size: 38KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert WB Anti-LOX 1 antibody, Western blotting All lanes: Anti LOX 1  at 0.5ug/ml Lane 1: HELA Whole Cell Lysate at 40ug Lane 2: SMMC Whole Cell Lysate at 40ug Lane 3: U87 Whole Cell Lysate at 40ug Lane 4: U937 Whole Cell Lysate at 40ug Lane 5: K562 Whole Cell Lysate at 40ug Predicted bind size:31 KD Observed bind size: 31KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert WB <b>WB Suggested Anti-OLR1 Antibody Titration: </b>2.5ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details

OLR1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-OLR1 Antikörper

  1. Human Polyclonal OLR1 Primary Antibody für IF (p), IHC (p) - ABIN676988 : Wu, Tang, Jiang, Li, Jiang, Liu: PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway. in Molecular and cellular biochemistry 2011 (PubMed)
    Show all 6 Pubmed References

  2. Human Polyclonal OLR1 Primary Antibody für IHC (fro), FACS - ABIN2475355 : Sawamura, Kume, Aoyama, Moriwaki, Hoshikawa, Aiba, Tanaka, Miwa, Katsura, Kita, Masaki: An endothelial receptor for oxidized low-density lipoprotein. in Nature 1997 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal OLR1 Primary Antibody für IF, ELISA - ABIN2475353 : Chen, Masaki, Sawamura: LOX-1, the receptor for oxidized low-density lipoprotein identified from endothelial cells: implications in endothelial dysfunction and atherosclerosis. in Pharmacology & therapeutics 2002 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal OLR1 Primary Antibody für IF, ELISA - ABIN2475354 : Li, Liu, Chen, Sawamura, Mehta: LOX-1, an oxidized LDL endothelial receptor, induces CD40/CD40L signaling in human coronary artery endothelial cells. in Arteriosclerosis, thrombosis, and vascular biology 2003 (PubMed)
    Show all 3 Pubmed References

  5. Mouse (Murine) Monoclonal OLR1 Primary Antibody für FACS - ABIN4897693 : Biedroń, Konopiński, Marcinkiewicz, Józefowski: Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages. in PLoS ONE 2015 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal OLR1 Primary Antibody für ELISA - ABIN1997147 : Hinagata, Kakutani, Fujii, Naruko, Inoue, Fujita, Mehta, Ueda, Sawamura: Oxidized LDL receptor LOX-1 is involved in neointimal hyperplasia after balloon arterial injury in a rat model. in Cardiovascular research 2005 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal OLR1 Primary Antibody für ICC, IF - ABIN4331395 : Chen, Qiu, Lin, Nam, Ogbu-Nwobodo, Archibald, Joslin, Wun, Sawamura, Green: Lectin-like oxidized low-density lipoprotein receptor (LOX-1) in sickle cell disease vasculopathy. in Blood cells, molecules & diseases 2016 (PubMed)

  8. Human Polyclonal OLR1 Primary Antibody für ELISA, WB - ABIN4331396 : Shi, Cosentino, Camici, Akhmedov, Vanhoutte, Tanner, Lüscher: Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells. in Arteriosclerosis, thrombosis, and vascular biology 2011 (PubMed)

Weitere Antikörper gegen OLR1 Interaktionspartner

Rabbit Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) Interaktionspartner

  1. ox-LDL and LOX-1 increase due to subarachnoid hemorrhage and they may play a role in the pathogenesis of vasospasm.

  2. LOX (zeige LOX Antikörper) and LOXL2 (zeige LOXL2 Antikörper) play an important role in wound healing after glaucoma filtration surgery. Targeting LOXL2 (zeige LOXL2 Antikörper) with an inhibitory monoclonal antibody (GS-607601) had a broader efficacy than targeting LOX (zeige LOX Antikörper), reducing angiogenesis and inflammation, and fibrosis.

  3. Angiotensin (1-7) inhibited LOX-1 expression and diminished Ang II (zeige AGT Antikörper)-mediated inflammation in endothelial cells

  4. Elevated LOX-1 expression and inflammatory responses are induced in hypercholesterolemic rabbits by Chlamydia pneumoniae GroEL1 heat shock protein.

  5. Early treatment with fluvastatin had a crucial endothelial protective effect by down-regulating LOX-1 expression level in atherosclerotic arteries in early atherosclerosis.

  6. LOX-1 expression appears to be closely associated with tissue factor (zeige F3 Antikörper) expression, apoptotic events and morphological vulnerability in atherosclerotic lesions

Human Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) Interaktionspartner

  1. LOX-1 signalling and the crucial role of cytokines

  2. High OLR1 expression is associated with breast cancer.

  3. Multiple classical molecular dynamics simulations have been applied to the human LOX-1 receptor to clarify the role of the Trp150Ala mutation in the loss of binding activity. Results indicate that the substitution of this crucial residue, located at the dimer interface, markedly disrupts the wild-type receptor dynamics

  4. Carrying the C allele of the rs11053646 variant of the OLR1 gene was associated with an increased risk of CAD (zeige CAD Antikörper) in heterozygous adult patients with FH, and this risk could be even greater in smokers as well as in younger patients.

  5. Berberine could prevent the oxLDL and TNFalpha (zeige TNF Antikörper) - induced LOX1 expression and oxidative stress, key events that lead to NOX, MAPK (zeige MAPK1 Antikörper)/Erk1/2 (zeige MAPK1/3 Antikörper) and NF-kappaB (zeige NFKB1 Antikörper) activation linked to endothelial dysfunction.

  6. Data suggest Klotho (zeige KL Antikörper) attenuates ox-LDL- (oxidized low density lipoprotein)-induced oxidative stress in vascular endothelial cells via up-regulation of oxidative scavengers (lipoprotein and nitric oxide), activation of the PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper)/eNOS (zeige NOS3 Antikörper) signaling, and down-regulation of LOX1 (lectin-like ox-LDL receptor (zeige LDLR Antikörper)) expression. (PI3K (zeige PIK3CA Antikörper) = phosphatidylinositol 3-Kinase; Akt (zeige AKT1 Antikörper) = proto-oncogene c-Akt (zeige AKT1 Antikörper); eNOS (zeige NOS3 Antikörper) = endothelial nitric oxide synthase (zeige NOS3 Antikörper))

  7. Individuals >/=30 years old with abdominal obesity presented lower Lox1 levels than patients >/=30 years old without abdominal obesity.

  8. These studies suggest that activation of LOX-1 expression occurs through binding of the chlamydial glycan and provides one mechanism by which Chlamydia pneumoniae infection could play a role in the pathogenesis of atherosclerosis.

  9. Elevated LOX1 is Associated with Acute Stroke.

  10. Xanthine oxidase (zeige XDH Antikörper) induces foam cell formation in large part through activation of LOX-1 - NLRP3 (zeige NLRP3 Antikörper) pathway in both vascular smooth muscle cells and THP-1 (zeige GLI2 Antikörper) cells.

Mouse (Murine) Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) Interaktionspartner

  1. At low oxLDL levels LOX-1 activates the protective Oct-1 (zeige POU2F1 Antikörper)/SIRT1 (zeige SIRT1 Antikörper) pathway, while at higher levels of the lipoprotein switches to the thrombogenic ERK1/2 (zeige MAPK1/3 Antikörper) pathway.

  2. The findings suggested that ox-LDL could induce cardiac hypertrophy through the direct association of AT1-R (zeige AGTR1 Antikörper) and LOX-1.

  3. Adiponectin, TNF-alpha (zeige TNF Antikörper), and LOX-1 exert complex regulatory effects on the coronary microvascular endothelial function in atherosclerotic ApoE (zeige APOE Antikörper) knockout mice.

  4. LOX-1 in cardiomyocytes plays an important role in the pathology of doxorubicin-induced cardiomyopathy. LOX-1 deletion altered the LOX-1-related signaling pathway, which led to improvements in cardiac function, myocardial inflammation, fibrosis and degenerative changes after DOX treatment.

  5. Therefore we concluded that HNG (zeige NRGN Antikörper) could inhibit ox-LDL-induced macrophage-derived foam cell formation, which occurs because of a decrease in lipid uptake and an increase in cholesterol efflux from macrophage cells.

  6. The study indicated that the LOX-1/ox-LDL system in chondrocytes plays a role in the pathogenesis of age-related knee knee osteoarthritis, which is potentially a target for preventing knee osteoarthritis progression.

  7. We demonstrated that varenicline upregulates expression of LOX-1 and CD36 (zeige CD36 Antikörper) significantly through alpha7 nAChR (zeige CHRNA7 Antikörper), thereby promoting oxLDL uptake in macrophages.

  8. this study shows that LOX-1 can regulate inflammation through regulation of generation of reactive oxygen species in in Aspergillus fumigatus keratitis

  9. The in vitro and in vivo models revealed that lipid metabolism disorder and FK506 caused oxidative stress and a fibrogenic response. In addition, decreased levels of LOX1 markedly reduced the levels of TGFb1 (zeige TGFB1 Antikörper) in the in vitro model.

  10. LOX-1/ox-LDL system plays a pivotal role in the pathogenesis of instability-induced osteoarthritis through endochondral ossification.

Cow (Bovine) Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) Interaktionspartner

  1. bta-miR (zeige MYLIP Antikörper)-370 has a negative regulatory effect on the OLR1 gene at both the gene and protein expression levels and has a role in lipid metabolism in bovine adipocytes

  2. Overexpression of LOX-1 leads to the attenuation of protective autophagy response in aortic endothelial cells.

  3. These results imply that the 3' UTR (zeige UTS2R Antikörper) SNP of the OLR1 gene is a strong candidate marker for selection in cattle breeding programs.

  4. Our data indicate that blocking the LOX-1 receptor signal pathway might be a promising way to improve steroid hormone concentrations in metabolically highly active female mammals

  5. In the present study, we show that inhibition of LOX-1 leads to a rearrangement of ceramide from the basal membrane toward the Golgi apparatus

  6. The downregulation of eNOS (zeige NOS3 Antikörper) by ox-low-density lipoprotein, as driven by LOX-1-mediated endoplasmic stress, is associated with the PI3K-Akt (zeige AKT1 Antikörper)-eNOS (zeige NOS3 Antikörper) signaling pathway.

  7. 3'-UTR (zeige UTS2R Antikörper) SNP assoicated with milk composition traits and somatic cell score

  8. Oxidized low-density lipoprotein receptor (zeige LDLR Antikörper) (OLR1) single nucleotide polymorphism haplotype is associated with milk fat yield and fat percentage

  9. synergistic effects of cyclic tensile stretch load and ox-LDL on cell viability and proteoglycan (zeige Vcan Antikörper) synthesis in chondrocytes, which may be mediated through enhanced expression of LOX-1

  10. Upregulates VEGF (zeige VEGFA Antikörper) expression in articular cartilage, at least in part, through activation of PPAR-gamma (zeige PPARG Antikörper).

OLR1 Antigen-Profil

Protein Überblick

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit OLR1

  • oxidized low density lipoprotein receptor 1 (OLR1) Antikörper
  • oxidized low density lipoprotein (lectin-like) receptor 1 (Olr1) Antikörper
  • oxidized low density lipoprotein receptor 1 (Olr1) Antikörper
  • CLEC8A Antikörper
  • LOX-1 Antikörper
  • LOX1 Antikörper
  • LOXIN Antikörper
  • Oldlr1 Antikörper
  • Oldr1 Antikörper
  • Olr1 Antikörper
  • PLOX-1 Antikörper
  • Scare1 Antikörper
  • SLOX1 Antikörper
  • SR-EI Antikörper

Bezeichner auf Proteinebene für OLR1

oxidised low density lipoprotein (lectin-like) receptor 1 , oxidized low density lipoprotein (lectin-like) receptor 1 , lectin-like oxLDL receptor 1 , lectin-like oxidized LDL receptor 1 , lectin-type oxidized LDL receptor 1 , ox-LDL receptor 1 , oxidized low-density lipoprotein receptor 1 , C-type lectin domain family 8 member A , hLOX-1 , ox LDL receptor 1 , oxidized low-density lipoprotein receptor 1, soluble form , scavenger receptor class E, member 1 , Lectin-like oxidized low-density lipoprotein receptor-1 , lectin-like oxidized low-density lipoprotein receptor , BLOX1 , LOX-1 , bLOX-1 , lectin-like oxidized LDL receptor-1 , oxidized low density lipoprotein receptor 1

GENE ID SPEZIES
473362 Pan troglodytes
486694 Canis lupus familiaris
100009322 Oryctolagus cuniculus
4973 Homo sapiens
108078 Mus musculus
140914 Rattus norvegicus
281368 Bos taurus
396724 Sus scrofa
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