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Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998. Zusätzlich bieten wir Ihnen Osteoclast Stimulating Factor 1 Kits (23) und Osteoclast Stimulating Factor 1 Proteine (18) und viele weitere Produktgruppen zu diesem Protein an.
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Data show that SH3P2 was phosphorylated on Ser (zeige SIGLEC1 Antikörper)(202) by ribosomal S6 kinase (zeige RPS6KB1 Antikörper) (RSK (zeige RPS6KA1 Antikörper)) in an ERK (zeige EPHB2 Antikörper) pathway-dependent manner, and such phosphorylation inhibited the ability of SH3P2 to suppress cell motility.
SH3P2, a novel component of adhesion sites, is involved in Cbl (zeige CBL Antikörper) and Src (zeige SRC Antikörper)-mediated pathways
The SH3 domain (zeige ITSN1 Antikörper) structure of osteoclast stimulating factor at atomic resolution provides an accurate framework for structure-based design of its inhibitors.
The peptide-binding groove of OSTF-SH3 domain adopts a conformation different from other SH3 domains and probably needs a conformational switch for binding to its proline-rich ligand; this status is possibly regulated by the C-terminal ankyrin repeats.
The results of this study suggested that regulation of the PTN (zeige PTN Antikörper) signaling pathways may constitute new therapeutic opportunities particularly in those neurological disorders characterized by increased PTN (zeige PTN Antikörper) cerebral levels and neuroinflammation.
these data indicate that PTN (zeige PTN Antikörper)-PTPRZ (zeige PTPRZ1 Antikörper)-A signaling controls the timing of oligodendrocyte precursor cell differentiation in vivo, in which the CS moiety of PTPRZ (zeige PTPRZ1 Antikörper) receptors maintains them in a monomeric active state until its ligand binding.
findings link pleiotrophin abundance in gliomas with survival in humans and mice, and show that pleiotrophin promotes glioma progression through increased VEGF deposition and vascular abnormalization.
antagonizes Brd2 (zeige BRD2 Antikörper) promoting cell differentiation associated with the neural tube: spinal cord neurogenesis and neural crest migration
PTN-mediated hematopoietic regeneration occurs in a RAS-dependent manner.
the absence of PTN (zeige PTN Antikörper) in vivo is associated with disruption of specific cognitive and affective processes
The results of this study indicated that PTN (zeige PTN Antikörper) may be a novel genetic factor of importance in alcohol use disorders.
data suggest that the spinal antinociceptive effects caused by stimulation of alpha2-adrenoceptors are differentially regulated by endogenous expression of PTN (zeige PTN Antikörper)
PTN (zeige PTN Antikörper) overexpression exerts various effects on sarcolemma ion channel expression/function and resting cytosolic calcium concentrations in soleus and extensor digitorum longus muscles.
Vivarium-housed Wt controls had higher levels of active TGF-beta1 (zeige TGFB1 Antikörper) and IL-2 (zeige IL2 Antikörper) in inguinal lymph nodes relative to PTN (zeige PTN Antikörper)-Tg mice.
Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998
osteoclast stimulating factor 1
, osteoclast-stimulating factor 1
, SH3 domain protein 3
, heparin affin regulatory peptide
, heparin-binding brain mitogen
, heparin-binding growth factor 8
, heparin-binding growth-associated molecule
, heparin-binding neurite promoting factor
, heparin-binding neurotorphic factor
, heparin-binding neutrophic factor
, osteoblast-specific factor 1
, osteoblastic cell factor