Ornithine Decarboxylase Antizyme 1 Proteine (OAZ1)

Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Zusätzlich bieten wir Ihnen OAZ1 Antikörper (30) und OAZ1 Kits (10) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
OAZ1 4946 P54368
OAZ1 18245 P54369
OAZ1 25502 P54370
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Showing 10 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 15 bis 19 Tage
$319.00
Details
Hefe Zebrafisch His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,530.00
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Hefe Xenopus laevis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,531.83
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Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,531.83
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Hefe Mesocricetus auratus His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,552.00
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,566.67
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,566.67
Details
Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 11 bis 12 Tage
$313.60
Details

OAZ1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,

Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Ornithine Decarboxylase Antizyme 1 (OAZ1) Interaktionspartnern

Human Ornithine Decarboxylase Antizyme 1 (OAZ1) Interaktionspartner

  1. Data show the the interplay between the enzyme ornithine decarboxylase (ODC) and two regulatory proteins: antizyme (Az) and inhibitor (AzIN).

  2. Results show that ornithine decarboxylase antizyme 1 (OAZ1) simultaneously inhibits the proliferation and induces the differentiation of oral cancer cells.

  3. To further understand its functions in CML (zeige BCR Proteine) pathogenesis, OAZ1 was overexpressed, and PCR array analysis was used to monitor the expression of key genes commonly involved in leukemia development.

  4. Gene expression studies have identified altered expression of ornithine decarboxylase antizyme 1 in suicide completers with a history of mood disorders.

  5. In the absence of amino acids, mTORC1 is inhibited, whereas mTORC2 (zeige CRTC2 Proteine) is activated, leading to the inhibition of global protein synthesis and increased AZ1 synthesis via a cap-independent mechanism.

  6. AZ_95-176 is the minimal AZ peptide that is fully functioning in the binding of ODC (zeige ODC1 Proteine) and AZI and inhibition of their function.

  7. the differences in residues 125 and 140 in ODC and AZI are responsible for the differential antizyme-binding affinities

  8. Data show that OAZ promotes the removal of Mps1 (zeige IDUA Proteine) from centrosomes, and centrosome overproduction caused by reducing OAZ activity requires Mps1 (zeige IDUA Proteine).

  9. These data together demonstrate the existence of a c-Jun (zeige JUN Proteine)-dependent mechanism regulating the abundance of the antiapoptotic DNp73 in response to genotoxic stress.

  10. Human AZI is capable of acting as a general inhibitor for all members of the antizyme family.

Mouse (Murine) Ornithine Decarboxylase Antizyme 1 (OAZ1) Interaktionspartner

  1. Interaction of polyamines and mTOR signaling in the synthesis of antizyme (AZ).

  2. we have generated transgenic mice overexpressing mouse antizyme 1 gene under its own regulatory sequences

  3. Ornithine decarboxylase antizyme expression reduces tumor incidence, multiplicity and size even in the absence of p53 (zeige TP53 Proteine).

  4. The activity of AZ1 was low in the virgin and involuting stages, but increased markedly during late pregnancy and early lactation.

  5. These data together demonstrate the existence of a c-Jun (zeige JUN Proteine)-dependent mechanism regulating the abundance of the antiapoptotic DNp73 in response to genotoxic stress.

  6. Testosterone treatment enhanced AZ1 and N1-SSAT (zeige SAT1 Proteine) mRNA levels in a time-dependent manner

  7. antizyme and glycosaminoglycans have roles in polyamine transport

  8. OAZ can alter the intensity and duration of the BMP4 (zeige BMP4 Proteine) stimulus through Smad6 (zeige SMAD6 Proteine)

  9. Az-1 has a central and meaningful role in modulation of polyamine homeostasis, and in regulating cellular proliferation and transformation properties.

  10. The data-driven docking results suggest that both proteins occupy the same binding site on Az1, with Az1 binding within a large groove in antizyme inhibitor (AzI) and Ornithine Decarboxylase (ODC (zeige ODC1 Proteine)).

Xenopus laevis Ornithine Decarboxylase Antizyme 1 (OAZ1) Interaktionspartner

  1. antizyme expression requires programmed,+1 ribosomal frameshifting

OAZ1 Protein Überblick

Protein Überblick

Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase and accelerates its degradation.

Genbezeichner und Symbole assoziert mit OAZ1

  • ornithine decarboxylase antizyme 1 (OAZ1)
  • ornithine decarboxylase antizyme 1 (Oaz1)
  • ornithine decarboxylase antizyme 1 S homeolog (oaz1.S)
  • ornithine decarboxylase antizyme 1a (oaz1a)
  • Antizyme Protein
  • AZ-1 Protein
  • AZ1 Protein
  • AZI Protein
  • AZS Protein
  • oaz Protein
  • oaz1 Protein
  • ODC-Az Protein
  • ODCAC Protein

Bezeichner auf Proteinebene für OAZ1

ODC-Az , antizyme 1 , ODC antizyme , ODC-Az-S , ornithine decarboxylase antizyme 1

GENE ID SPEZIES
4946 Homo sapiens
18245 Mus musculus
25502 Rattus norvegicus
506973 Bos taurus
395746 Gallus gallus
379737 Xenopus laevis
101826304 Mesocricetus auratus
259192 Danio rerio
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