anti-Ornithine Carbamoyltransferase (OTC) Antikörper

This nuclear gene encodes a mitochondrial matrix enzyme. Zusätzlich bieten wir Ihnen Ornithine Carbamoyltransferase Kits (37) und Ornithine Carbamoyltransferase Proteine (25) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
OTC 5009 P00480
OTC 25611 P00481
OTC 18416 P11725
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Top anti-Ornithine Carbamoyltransferase Antikörper auf antikoerper-online.de

Showing 10 out of 102 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-OTC Antibody Titration: 2.5ug/mlPositive Control: HepG2 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of OTC Antibody (Center) (ABIN390915) in HepG2 cell line lysates (35 µg/lane). OTC (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatoarcinoma with OTC Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IHC (p), IHC, WB Immunohistochemistry-Paraffin: Ornithine Carbamoyltransferase Antibody [NBP1-31582] - Paraffin-embedded Colon ca, using antibody at 1:250 dilution. Western Blot: Ornithine Carbamoyltransferase Antibody [NBP1-31582] - Sample (20 ug of whole cell lysate) A: mouse Liver 10% SDS PAGE, antibody diluted at 1:30000. 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
361,00 €
Details
Human Kaninchen Unkonjugiert EIA, WB   0.4 mL Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), SimWes, WB Immunocytochemistry/Immunofluorescence: Ornithine Carbamoyltransferase Antibody [NBP1-87408] - Staining of human cell line U-2 OS shows positivity in mitochondria. Immunohistochemistry-Paraffin: Ornithine Carbamoyltransferase Antibody [NBP1-87408] - Staining of human liver shows cytoplasmic positivity in hepatocytes. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: Ornithine Carbamoyltransferase Antibody [NBP1-88121] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 12% SDS PAGE antibody diluted at 1:500 IHC-P Image Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using OTC, antibody at 1:250 dilution. 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat intestine tissue labeled with Anti OTC Polyclonal Antibody, Unconjugated (ABIN720505) at 1:200 followed by conjugation to the secondary antibody and DAB staining Human HepG2 cells probed with OTC Polyclonal Antibody, unconjugated  at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 90 minutes at 37°C. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Details

OTC Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus)


Mouse (Murine)


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Am meisten referenzierte anti-Ornithine Carbamoyltransferase Antikörper

  1. Cow (Bovine) Polyclonal OTC Primary Antibody für IHC, WB - ABIN2773791 : Tanaka, Wada, Maruyama, Tanaka, Takikawa, Komatsu: Hyperammonemia-induced encephalopathy due to ornithine transcarbamylase deficiency in an adult woman: identification of novel missense mutations. in Journal of gastroenterology 2005 (PubMed)
    Zeige alle 4 Referenzen für 2773791

  2. Human Polyclonal OTC Primary Antibody für IHC (p), IHC - ABIN441580 : McGuire, Tarasenko, Wang, Levy, Zerfas, Moran, Lee, Bequette, Diaz: Acute metabolic decompensation due to influenza in a mouse model of ornithine transcarbamylase deficiency. in Disease models & mechanisms 2014 (PubMed)
    Zeige alle 3 Referenzen für 441580

  3. Human Polyclonal OTC Primary Antibody für ICC, IF - ABIN4341629 : Chaerkady, Harsha, Nalli, Gucek, Vivekanandan, Akhtar, Cole, Simmers, Schulick, Singh, Torbenson, Pandey, Thuluvath: A quantitative proteomic approach for identification of potential biomarkers in hepatocellular carcinoma. in Journal of proteome research 2008 (PubMed)
    Zeige alle 2 Referenzen für 4341629

  4. Human Polyclonal OTC Primary Antibody für IHC, IHC (p) - ABIN4341630 : Montes-Nieto, Fuentes-Almagro, Bonilla-Valverde, Prieto-Alamo, Jurado, Carrascal, Gómez-Ariza, López-Barea, Pueyo: Proteomics in free-living Mus spretus to monitor terrestrial ecosystems. in Proteomics 2007 (PubMed)

  5. Human Polyclonal OTC Primary Antibody für FACS, IHC (p) - ABIN390915 : Hansmannel, Lendon, Pasquier, Dumont, Hannequin, Chapuis, Laumet, Ayral, Galimberti, Scarpini, Campion, Amouyel, Lambert: Is the ornithine transcarbamylase gene a genetic determinant of Alzheimer's disease? in Neuroscience letters 2008 (PubMed)

Weitere Antikörper gegen Ornithine Carbamoyltransferase Interaktionspartner

Human Ornithine Carbamoyltransferase (OTC) Interaktionspartner

  1. In Korean patients with OTC deficiency, mutations in OTC are genetically heterogeneous.

  2. Sanger sequencing of the ornithine transcarbamylase (OTC) gene revealed a novel hemizygous deletion at the fourth nucleotide of intron 4 (c.386+4delT) in a child with hyperammonemia and his asymptomatic mother.

  3. Ornithine transcarbamylase deficiency was genetically heterogeneous in seven Korean patients with confirmed ornithine transcarbamylase deficiency diagnosis by biochemical findings and/or genetic analysis, together with two novel mutations in the OTC gene

  4. The corresponding OTC tissue enzyme activities were between 3-6% of normal control in mouse and human liver. The use of the cryptic splice sites was reproduced in minigenes carrying murine or human mutant sequences

  5. OTC mutation and phenotype in ornithine transcarbamylase deficiency

  6. aim of this study was to provide clues for recognition of OTCD in adults and analyze the environmental factors that, interacting with OTC gene mutations, might have triggered acute clinical manifestations

  7. HNF-4alpha (zeige HNF4A Antikörper) most likely plays an essential role in the initiation of OTC transcription in human.

  8. Data indicate that all of the three patients have carried ornithine transcarbamylase gene mutations, patients 1 and 2 were both hemizygous for mutation c.586G> A(p.D196N).

  9. V339G and W332S mutations of OTC have been discovered for the first time

  10. carriers of the ornithine transcarbamylase (OTC) mutation are at risk for developing hyperammonemia coma during the postpartum period and at times of metabolic stress.

Mouse (Murine) Ornithine Carbamoyltransferase (OTC) Interaktionspartner

  1. Gene correction in adult OTC-deficient mice was lower and accompanied by larger deletions that ablated residual expression from the endogenous OTC gene, leading to diminished protein tolerance and lethal hyperammonemia on a chow diet

  2. The corresponding OTC tissue enzyme activities were between 3-6% of normal control in mouse and human liver. The use of the cryptic splice sites was reproduced in minigenes carrying murine or human mutant sequences

  3. Serum OCT (zeige Plxna2 Antikörper) seemed to reflect tumor necrosis factor-alpha (zeige TNF Antikörper)-mediated hepatic damage in diabetic obese mice and could be useful in the application for non-alcoholic fatty liver disease with features of metabolic syndrome, such as obesity and diabetes.

  4. in vivo regulation by HNF4alpha (zeige HNF4A Antikörper)

  5. Results highlight the importance of the interaction between the OTC spf-ash mutation (ornithine transcarbamylase deficiency) and genetic backgrounds on metabolic phenotypes (ureagenesis, arginine metabolism, and nitric oxide production).

  6. Phenotypic correction of OTC deficiency using low-dose helper-dependent adenoviral vectors is reported.

  7. Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.

Ornithine Carbamoyltransferase (OTC) Antigen-Profil

Protein Überblick

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.

Genbezeichner und Symbole assoziert mit OTC

  • ornithine carbamoyltransferase (OTC) Antikörper
  • ornithine carbamoyltransferase (argF) Antikörper
  • ornithine carbamoyltransferase (argF-2) Antikörper
  • ornithine carbamoyltransferase (atpD-2) Antikörper
  • ornithine carbamoyltransferase (CNC04300) Antikörper
  • ornithine carbamoyltransferase (Otc) Antikörper
  • ornithine transcarbamylase (Otc) Antikörper
  • AI265390 Antikörper
  • BA4351 Antikörper
  • F1B16.13 Antikörper
  • F1B16_13 Antikörper
  • OCTD Antikörper
  • ornithine carbamoyltransferase Antikörper
  • PSPTO4164 Antikörper
  • Sf Antikörper
  • spf Antikörper

Bezeichner auf Proteinebene für OTC

ornithine carbamoyltransferase , OTCase , ornithine carbamoyltransferase, mitochondrial , ornithine transcarbamylase , sparse fur

GENE ID SPEZIES
100050268 Equus caballus
1087574 Bacillus anthracis str. Ames
1168159 Shewanella oneidensis MR-1
1185844 Pseudomonas syringae pv. tomato str. DC3000
1790857 Rhodopirellula baltica SH 1
2687999 Geobacter sulfurreducens PCA
2797905 Listeria monocytogenes serotype 4b str. F2365
3105054 Methylococcus capsulatus str. Bath
3195160 Ruegeria pomeroyi DSS-3
3229331 Dehalococcoides ethenogenes 195
3231583 Campylobacter jejuni RM1221
3256472 Cryptococcus neoformans var. neoformans JEC21
3728051 Carboxydothermus hydrogenoformans Z-2901
3927820 Ehrlichia chaffeensis str. Arkansas
5009 Homo sapiens
480878 Canis lupus familiaris
397438 Sus scrofa
280887 Bos taurus
25611 Rattus norvegicus
395735 Gallus gallus
101102207 Ovis aries
843869 Arabidopsis thaliana
18416 Mus musculus
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