Nuclear ssembly factor 1 ribonucleoprotein Proteine (NAF1)

RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis.

alle Proteine anzeigen Gen GeneID UniProt
Maus NAF1 NAF1 234344 Q3UMQ8
Ratte NAF1 NAF1 306387 Q52KK4
Human NAF1 NAF1 92345 Q96HR8
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Weitere Proteine zu Nuclear ssembly factor 1 ribonucleoprotein (NAF1) Interaktionspartnern

Human Nuclear ssembly factor 1 ribonucleoprotein (NAF1) Interaktionspartner

  1. Data indicate that disease in NAF1 (zeige TNIP1 Proteine) mutation carriers is telomere-mediated; they show that NAF1 (zeige TNIP1 Proteine) haploinsufficiency selectively disturbs telomere length homeostasis by decreasing the levels of telomerase RNA while sparing rRNA pseudouridylation.

  2. Naf1 (zeige TNIP1 Proteine) contributes to the maintenance of HIV-1 latency by inhibiting long terminal repeat driven HIV-1 gene transcription in a nuclear factor kappa B-dependent manner.

Nuclear ssembly factor 1 ribonucleoprotein (NAF1) Protein Überblick

Protein Überblick

RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4 (By similarity).

Genbezeichner und Symbole assoziert mit NAF1

  • nuclear assembly factor 1 ribonucleoprotein (Naf1)
  • nuclear assembly factor 1 ribonucleoprotein (NAF1)
  • Gm174 Protein
  • RGD1306802 Protein

Bezeichner auf Proteinebene für NAF1

H/ACA ribonucleoprotein complex non-core subunit NAF1 , nuclear assembly factor 1 homolog

GENE ID SPEZIES
234344 Mus musculus
306387 Rattus norvegicus
92345 Homo sapiens
514182 Bos taurus
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