Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2) ELISA Kits

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Zusätzlich bieten wir Ihnen NFE2 Antikörper (40) und NFE2 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human NFE2 NFE2 4778 Q16621
Anti-Maus NFE2 NFE2 18022 Q07279
Anti-Ratte NFE2 NFE2 366998 Q6AYT2
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Weitere ELISA Kits für NFE2 Interaktionspartner

Human Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2) Interaktionspartner

  1. NF-E2, TAL1 (zeige TAL1 ELISA Kits) and KLF1 (zeige KLF1 ELISA Kits), all activators play a primary role in HSs (zeige GFER ELISA Kits) formation in the LCR

  2. under the obese condition, activation of the hepatic NFE2/miR (zeige MLXIP ELISA Kits)-423-5p axis plays important roles in the progression of type 2 diabetes and NAFLD (zeige TSC2 ELISA Kits) by repressing the FAM3A (zeige FAM3A ELISA Kits)-ATP-Akt (zeige AKT1 ELISA Kits) signaling pathway.

  3. Our data presented herein support the hypothesis that cytoplasmically located NF-E2 may have a function in the elimination of internal organelles. The mild autophagy defect observed in our mice may be due to the requirement for additional proteins in the formation of larger complexes to exert this function.

  4. assessment of NF-E2 and NGFR (zeige NGFR ELISA Kits) expression may provide additional support in reaching a correct diagnosis in discriminating polycythemia vera (zeige IGF2BP3 ELISA Kits) from prefibrotic/fibrotic primary myelofibrosis and essential thrombocythemia

  5. The genes BCL6 (zeige BCL6 ELISA Kits), NFE2, POU4F2 (zeige POU4F2 ELISA Kits) and ELF4 are primary 1,25(OH)2D3 targets in THP-1 (zeige GLI2 ELISA Kits) cells

  6. the RUNX1 (zeige RUNX1 ELISA Kits) target NF-E2 is part of the molecular network by which RUNX1 (zeige RUNX1 ELISA Kits) regulates platelet biogenesis and function in a pedigree with familial platelet disorder with a predisposition to acute myelogenous leukemia

  7. A functional link among the erythroid transcription factors GATA-1 (zeige GATA1 ELISA Kits)/NF-E2, miR (zeige MLXIP ELISA Kits)-199b-5p in erythropoiesis.

  8. NF-E2 immunohistochemistry and analysis of the proportion of nuclear positive erythroblasts of all erythroid precursor cells can help to distinguish between ET and PMF (zeige PRB1 ELISA Kits) even in early stages of the diseases.

  9. NFE-2 transgene mediates the expression of interleukin 8 (zeige IL8 ELISA Kits) in myeloproliferative neoplasms, thereby contributing to myeloproliferative neoplasm pathology.

  10. Findings suggest a model whereby ROCK inhibition drives polyploidization, DMS growth and proplatelet formation late in megakaryocyte maturation through downregulation of MYC (zeige MYC ELISA Kits) and NFE2 expression.

Mouse (Murine) Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2) Interaktionspartner

  1. Under the obese condition, activation of the hepatic NFE2/miR (zeige MLXIP ELISA Kits)-423-5p axis plays important roles in the progression of type 2 diabetes and NAFLD (zeige TSC2 ELISA Kits) by repressing the FAM3A (zeige FAM3A ELISA Kits)-ATP-Akt (zeige AKT1 ELISA Kits) signaling pathway.

  2. results suggest that Nrf2 (zeige NFE2L2 ELISA Kits) deficiency induced by HFD promoted hepatic fatty acid metabolism disorder by altering 18-carbon and 22-carbon fatty acid composition

  3. A novel murine model may excellently describe the deleterious impact of sustained chronic NF-E2 overexpression during uncontrolled chronic inflammation upon the hematopoietic system--the development of clonal myeloproliferation.

  4. Although none of the parameters measured were different between the NF-E2 deficient and control mice, an increase in calcium (21%) and an increase in the mineral/matrix ratio (32%) was observed in GATA-1 (zeige GATA1 ELISA Kits) deficient mice.

  5. By activating genes in megakaryocytes that mediate platelet production and function, NF-E2 p45 determines the quantity and quality of platelets.

  6. maintaining expression of intestinal epithelial cell prohibitin (zeige PHB ELISA Kits) reduces the severity of inflammation and increases colonic levels of the antioxidants HO-1 (zeige HMOX1 ELISA Kits) and NQO-1 (zeige NQO1 ELISA Kits) via a mechanism independent of Nfe2

  7. These findings demonstrate that a combination of p45NF-E2, Maf (zeige MAF ELISA Kits) G, and Maf (zeige MAF ELISA Kits) K is a key determinant of both megakaryopoiesis and thrombopoiesis.

  8. Loss of p45 NF-E2 leads to a 2-fold increase in serum erythropoietin (zeige EPO ELISA Kits) & increased splenic erythropoiesis. Erythroid cells were arrested at the G(1) stage of cell cycle.

  9. Nfe2 modulates JunD (zeige JUND ELISA Kits) binding to the Gcm1 (zeige GCM1 ELISA Kits) promoter via acetylation

  10. studies identify a novel function of p45NF-E2 during placental development: in trophoblast cells, p45NF-E2 represses Gcm1 (zeige GCM1 ELISA Kits) and syncytiotrophoblast formation via acetylation

NFE2 Antigen-Profil

Beschreibung des Gens

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Genbezeichner und Symbole assoziert mit NFE2

  • nuclear factor (erythroid-derived 2), 45kDa (NFE2) Antikörper
  • nuclear factor, erythroid 2 (NFE2) Antikörper
  • nuclear factor, erythroid derived 2 (Nfe2) Antikörper
  • 45kDa Antikörper
  • NF-E2 Antikörper
  • p45 Antikörper
  • p45nf-e2 Antikörper
  • p45NFE2 Antikörper

Bezeichner auf Proteinebene für NFE2

leucine zipper protein NF-E2 , nuclear factor, erythroid derived 2 , nuclear factor, erythroid-derived 2 45 kDa subunit , p45 NF-E2 , transcription factor NF-E2 45 kDa subunit , nuclear factor (erythroid-derived 2), 45kD , nuclear factor (erythroid-derived 2), 45kDa , nuclear factor, erythroid derived 2, 45 kDa

GENE ID SPEZIES
486495 Canis lupus familiaris
514006 Bos taurus
4778 Homo sapiens
18022 Mus musculus
366998 Rattus norvegicus
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