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anti-Nodal Homolog (Mouse) (NODAL) Antikörper

The protein encoded by NODAL is a member of the TGF-beta superfamily. Zusätzlich bieten wir Ihnen Nodal Kits (4) und Nodal Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NODAL 294503  
NODAL 18119 P43021
NODAL 4838 Q96S42
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Katalog Nr. Reaktivität Wirt Konjugat Applikation Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ICC, IF, WB 50 μL Anmelden zum Anzeigen 2 bis 3 Tage
498,00 €
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NODAL Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Rat (Rattus) , ,

Mouse (Murine) , ,

Human , ,

Weitere Antikörper gegen Nodal Interaktionspartner

Cow (Bovine) Nodal Homolog (Mouse) (NODAL) Interaktionspartner

Mouse (Murine) Nodal Homolog (Mouse) (NODAL) Interaktionspartner

  1. The finding that Foxh1 (zeige FOXH1 Antikörper)-Grg (zeige AES Antikörper)-mediated repression is not essential for Nodal expression during mouse embryogenesis suggests that other regulators compensate for the loss of repressive regulatory input that is mediated by Grg (zeige AES Antikörper) interactions.

  2. The Nodal morphogen (zeige SHH Antikörper) gradient induces distinct gene expression patterns during zebrafish embryogenesis.

  3. HEB (zeige FREM1 Antikörper) is a fundamental link between Nodal signalling, the derepression of a specific class of poised promoters during differentiation, and lineage specification in mouse embryonic stem cells

  4. Studies indicate that the pair of Nodal and Lefty (Lefty1 and Lefty2 (zeige LEFTY2 Antikörper)) has a conserved role in left-right asymmetry.

  5. Studies indicate that Nodal/Smad2 (zeige SMAD2 Antikörper)-dependent signals govern initial proximal-distal polarity and formation of the anterior visceral endoderm (AVE).

  6. Meteorin (zeige METRN Antikörper) is a novel regulator of Nodal transcription

  7. This implies that Gdf1 (zeige GDF1 Antikörper) potentiates Nodal activity by stabilizing a low molecular weight fraction that is susceptible to neutralization by soluble Acvr2 (zeige ACVR2A Antikörper).

  8. The consequent prolonged Nodal activity in the node by the absence of Cerl2 (zeige DAND5 Antikörper) affects local Nodal expression and prolongs its expression in the lateral plate mesoderm.

  9. The combined inhibition of Nodal and BMP signaling resulted in the accumulation of Nanog-negative cells, even in the presence of LIF, uncovering a shared role for BMP and Nodal signaling in maintaining Nanog expression and repression of differentiation.

  10. Snail (zeige SNAI1 Antikörper) knockdown abolished the Nodal-induced epithelial-mesenchymal transition in B16 cells

Human Nodal Homolog (Mouse) (NODAL) Interaktionspartner

  1. The MSX2 controls mesendoderm lineage commitment by simultaneous suppression of SOX2 (zeige SOX2 Antikörper) and induction of NODAL expression through direct binding and activation of the Nodal promoter.

  2. During a maturation phase, a fast acting NODAL loop stimulates its own activity and temporarily inhibits BMP signaling. During the stabilization phase, a slow acting NODAL loop, involving WNTs re-establishes BMP signaling and the pluripotency circuitry.

  3. Nodal signaling pathway has subtle changes in the endometrium of women with endometriosis, but this imbalance may not cause functional damage as it seems not to affect the nuclear expression of SMAD4 (zeige SMAD4 Antikörper).

  4. The expression of lefty (zeige LEFTY2 Antikörper) in RCC (zeige XRCC1 Antikörper) cells was lower than that in adjacent non-tumor cells, which may result in the overexpression of nodal, thereby promoting the growth of RCC (zeige XRCC1 Antikörper).

  5. Nodal induces signal transduction through the Smad2 (zeige SMAD2 Antikörper)/3-dependent pathway in vitro. Results that Nodal promotes pancreatic cancer cell migration and invasion and induces epithelial-mesenchymal transition.

  6. we found that Kl treatment impairs Nodal mRNA expression and Fgf9-mediated Nanos2 (zeige NANOS2 Antikörper) induction, reinforcing the antagonistic effect of these two growth factors on the meiotic fate of male germ cells

  7. our studies provide mechanistic insights into Nodal signaling and Nodal inhibition with Cerberus (zeige CER1 Antikörper) and highlight the potential value of Cerberus (zeige CER1 Antikörper) as anti-Nodal therapeutic.

  8. Lefty (zeige LEFTY2 Antikörper) reduced the levels of phosphorylated Smad2 (zeige SMAD2 Antikörper), Smad3 (zeige SMAD3 Antikörper), and ERK1/2 (zeige MAPK1/3 Antikörper), inhibited the proliferation and invasion of glioma cells, and increased their apoptosis.

  9. The data suggest that ERK (zeige EPHB2 Antikörper) activation by Nodal signaling regulates c-myc (zeige MYC Antikörper) and p27 (zeige PAK2 Antikörper) proteins post-translationally and that this cascade is essential for aggressive breast tumor behavior in vivo.

  10. Inhibition of activin (zeige Actbeta Antikörper)/nodal signaling leads to formation of extravillous trophoblast, whereas loss of activin (zeige Actbeta Antikörper)/nodal inhibition leads to the formation of syncytiotrophoblasts

Xenopus laevis Nodal Homolog (Mouse) (NODAL) Interaktionspartner

  1. Data show taht combined Wnt (zeige WNT2 Antikörper) and Nodal signaling synergistically activates transcription of Spemann organizer genes.

  2. Data suggest that Coco (zeige DAND5 Antikörper) acts as a critical target of flow, suggesting that symmetry is broken by flow-mediated left-asymmetric release of Nodal repression at the midline.

  3. Data show that rapid differential transport of Nodal and Lefty (zeige LEFTY2 Antikörper) on sulfated (zeige SULF1 Antikörper) proteoglycan (zeige Vcan Antikörper)-rich extracellular matrix regulates left-right asymmetry in Xenopus.

  4. Unilateral expression of Xnr-1 in the left lateral plate mesoderm directs the orientation of the left-right axis by driving the left-specific gene cascade.

  5. asymmetric expression of Nodal-related 1 (Xnr1) begins in the posterior left lateral plate mesoderm shortly after the initiation of bilateral perinotochordal expression in the posterior tailbud

  6. Xnr1 and derriere (zeige GDF3 Antikörper) are coexpressed in the posterior paraxial mesoderm at neurula stage, and with Coco (zeige DAND5 Antikörper) define a posttranscriptionally regulated signaling center in the chain leading to an increased TGF-beta (zeige TGFB1 Antikörper) signal on the left side of the embryo.

Nodal (NODAL) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the TGF-beta superfamily. Studies of the mouse counterpart suggested that this gene may be essential for mesoderm formation and subsequent organization of axial structures in early embryonic development.

Genbezeichner und Symbole assoziert mit NODAL

  • nodal growth differentiation factor (Nodal) Antikörper
  • nodal homolog (mouse) (NODAL) Antikörper
  • nodal (Nodal) Antikörper
  • nodal growth differentiation factor (NODAL) Antikörper
  • nodal growth differentiation factor (nodal) Antikörper
  • nodal homolog 1 (nodal1) Antikörper
  • HTX5 Antikörper
  • nodal Antikörper
  • nodal4 Antikörper
  • nodal4-A Antikörper
  • nr1 Antikörper
  • nr1-A Antikörper
  • nr4 Antikörper
  • Tg.413d Antikörper
  • Xnr-1 Antikörper
  • xnr4 Antikörper

Bezeichner auf Proteinebene für NODAL

nodal-related protein 1 , nodal homolog (mouse) , nodal homolog , Nodal protein , nodal homolog-like , early embryo mesoderm formation , transgenic lethal 413.d , Nodal homolog 4 , Xnr-4 , nodal homolog 4-A , nodal-related protein 4-A , nodal-related 1, induction of axial mesoderm , nr-1 , xnr1

GENE ID SPEZIES
294503 Rattus norvegicus
395205 Gallus gallus
466100 Pan troglodytes
489028 Canis lupus familiaris
530748 Bos taurus
710424 Macaca mulatta
780406 Sus scrofa
100406643 Callithrix jacchus
100453474 Pongo abelii
100588745 Nomascus leucogenys
18119 Mus musculus
4838 Homo sapiens
398068 Xenopus laevis
378543 Xenopus laevis
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