Nidogen 2 Proteine (NID2)

NID2 encodes a member of the nidogen family of basement membrane proteins. Zusätzlich bieten wir Ihnen Nidogen 2 Antikörper (57) und Nidogen 2 Kits (19) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
NID2 18074 O88322
NID2 22795 Q14112
Ratte NID2 NID2 302248 B5DFC9
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Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
609,52 €
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NID2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , ,
, ,

Weitere Proteine zu Nidogen 2 (NID2) Interaktionspartnern

Mouse (Murine) Nidogen 2 (NID2) Interaktionspartner

  1. Nidogen-2, a protein shown to be expressed intracellularly and for secretion by pre-adipocytes, was shown to interact, through its globular G3 domain, with TRAP 5a in vitro.

  2. show that loss of nidogen 2, but not of nidogen 1 (zeige NID1 Proteine), promotes lung metastasis of melanoma cells. Histological and ultrastructural analysis of nidogen 1 (zeige NID1 Proteine)- and 2-deficient lungs did not reveal differences in morphology and ultrastructure of basement membrane

  3. Basement membrane deposition of nidogen 1 but not nidogen 2 requires the nidogen binding module of the laminin gamma1 chain.

  4. These findings revealed extensive coregulation of nidogen-1 (zeige NID1 Proteine) and -2 expression and much more complementary functions of the two nidogens than previously recognized.

  5. Nid2 is essential for late stages of lung development and for maintenance and/or integrity of cardiac tissue

  6. nidogen-2 is equivalent to nidogen-1 (zeige NID1 Proteine) in skin-organotypic coculture, and both can promote the development of a functional basement membrane zone

  7. nidogen-1 (zeige NID1 Proteine) and -2 have roles in development of the ectodermal basement membrane of the limb bud

  8. decreased expression of the entactin-2 gene after treatment of the cells with ent-2 (zeige SLC29A2 Proteine)-specific siRNA preparation led to reduced expression of the cell cycle inhibitor p21

  9. The lack of nidogen-1 (zeige NID1 Proteine), nidogen-2, or both nidogens, plays no crucial role in the occurrence and localization of laminin-111, collagen type IV (zeige COL4 Proteine), and perlecan (zeige HSPG2 Proteine) in murine tubular renal basement membranes.

  10. In capillaries, basement membrane formation is severely impaired in the absence of nidogen-1 (zeige NID1 Proteine) and -2, showing an irregular, patchy distribution and a dramatically reduced deposition of collagen IV (zeige COL4 Proteine), perlecan (zeige HSPG2 Proteine), and particularly laminin-411.

Human Nidogen 2 (NID2) Interaktionspartner

  1. Knockdown of nidogen-2 reduced SOX9 (zeige SOX9 Proteine) expression, whereas it up-regulated RUNX2 (zeige RUNX2 Proteine) expression

  2. The cleavage of nidogen-1 (zeige NID1 Proteine) and -2 is partially inhibited in human tumor samples.

  3. combined methylation analysis of Twist homolog 1 (zeige TWIST1 Proteine) and nidogen-2 genes may be a simple, noninvasive, sensitive, and specific method for detecting cancer cells in urine.

  4. Decreased nidogen-2 expression is associated with hepatocellular carcinoma

  5. NID2 promoter hypermethylation is associated with oral cavity squamous cell carcinoma.

  6. Nidogen-2 is a new biomarker for ovarian cancer which correlates closely with CA125 (zeige MUC16 Proteine).

  7. short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin, nidogen-1 (zeige NID1 Proteine), fibulin-1 (zeige FBLN1 Proteine) and fibulin-2 (zeige FBLN2 Proteine)

  8. Nidogen-2 compensation hypothesis to explain limited phenotype observed following elimination of nidogen-1 (zeige NID1 Proteine) gene.

  9. nidogen-2 is equivalent to nidogen-1 (zeige NID1 Proteine) in skin-organotypic coculture, and both can promote the development of a functional basement membrane zone

  10. CpG islands of both NID1 (zeige NID1 Proteine) and NID2 genes are aberrantly methylated in human cancer samples and cancer cell lines.

Nidogen 2 (NID2) Protein Überblick

Protein Überblick

This gene encodes a member of the nidogen family of basement membrane proteins. This protein is a cell-adhesion protein that binds collagens I and IV and laminin and may be involved in maintaining the structure of the basement membrane.

Genbezeichner und Symbole assoziert mit Nidogen 2 Proteine (NID2)

  • nidogen 2 (Nid2)
  • nidogen 2 (osteonidogen) (NID2)
  • nidogen 2 (osteonidogen) (Nid2)
  • AW547149 Protein
  • entactin-2 Protein
  • Ly111 Protein
  • NID-2 Protein
  • nidogen-2 Protein

Bezeichner auf Proteinebene für Nidogen 2 Proteine (NID2)

entactin 2 , nidogen-2 , osteonidogen

GENE ID SPEZIES
18074 Mus musculus
22795 Homo sapiens
521854 Bos taurus
302248 Rattus norvegicus
100156994 Sus scrofa
Ausgewählte Anbieter für Nidogen 2 Proteine (NID2)
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