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NID1 encodes a member of the nidogen family of basement membrane glycoproteins. Zusätzlich bieten wir Ihnen Nidogen 1 Antikörper (121) und Nidogen 1 Kits (15) und viele weitere Produktgruppen zu diesem Protein an.
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Analysis of nidogen-1 and laminin-gamma1 interaction reveals multiple binding modes.
These studies provide strong evidence for a pathophysiological link between meprin beta (zeige MEP1B Proteine) and urinary excretion of cleaved nidogen-1 during cisplatin-induced acute kidney injury.
The C-terminal domains of mouse laminin gamma 1 (zeige LAMC1 Proteine) and nidogen 1 mediate interactions complex formation.
nidogen-1 is essential to provide an anti-angiogenic environment of differentiated vessels.
show that loss of nidogen 2 (zeige NID2 Proteine), but not of nidogen 1, promotes lung metastasis of melanoma cells. Histological and ultrastructural analysis of nidogen 1- and 2-deficient lungs did not reveal differences in morphology and ultrastructure of basement membrane
Basement membrane deposition of nidogen 1 but not nidogen 2 requires the nidogen binding module of the laminin gamma1 chain.
This study demonstrates that nidogen-1 is essential for maintenance of normal hippocampal excitability and synaptic plasticity.
Results suggest a non-structural role for nidogen 1 in wound repair.
short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin, nidogen-1, fibulin-1 (zeige FBLN1 Proteine) and fibulin-2 (zeige FBLN2 Proteine)
Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development.
nidogen-1 degraded by CatS can be quantified in serum by the NIC (zeige NCSTN Proteine) assay. The current data strongly suggest that cathepsin-S (zeige CTSS Proteine) degradation of nidogen-1 is strongly associated with NSCLC, which needs validation in larger clinical cohorts.
Differential protein expression of collagen IV (zeige COL4 Proteine), laminin alpha2, and nidogen-1 indicated basal lamina remodeling develops in ischemic failing versus nonfailing human hearts.
NID1 was confirmed as a target gene of MiR (zeige MLXIP Proteine)-192/215 in Hirschsprung's disease patients.
Increase of NID1 protein expression is associated with endometrial cancer invasion.
The cleavage of nidogen-1 and -2 is partially inhibited in human tumor samples.
results demonstrate that mutation in either NID1 or LAMC1 (zeige LAMC1 Proteine) disrupts the interaction NID1-LAMC1 (zeige LAMC1 Proteine) complex; findings implicate the extracellular matrix in the pathogenesis of Dandy-Walker spectrum disorders
Cleavage of nidogen-1 by cathepsin S (zeige CTSS Proteine) impairs its binding to basement membrane partners
NID1 gene is a biologically plausible locus for nevogenesis and melanoma development
nidogen-2 (zeige NID2 Proteine) is equivalent to nidogen-1 in skin-organotypic coculture, and both can promote the development of a functional basement membrane zone
CpG islands of both NID1 and NID2 (zeige NID2 Proteine) genes are aberrantly methylated in human cancer samples and cancer cell lines.
This gene encodes a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes, and may play a role in cell interactions with the extracellular matrix.
, nidogen (enactin)
, Nidogen precursor (Entactin)
, entactin 1
, nidogen (entactin)