Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) ELISA Kits

NMNAT2 product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Zusätzlich bieten wir Ihnen NMNAT2 Antikörper (34) und NMNAT2 Proteine (18) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human NMNAT2 NMNAT2 23057 Q9BZQ4
Anti-Maus NMNAT2 NMNAT2 226518 Q8BNJ3
Anti-Ratte NMNAT2 NMNAT2 289095 Q0HA29
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Weitere ELISA Kits für NMNAT2 Interaktionspartner

Human Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) Interaktionspartner

  1. Data indicate a chaperone function of nicotinamide mononucleotide adenylyl transferase (zeige NMNAT1 ELISA Kits) 2 (NMNAT2), independent from its enzymatic activity, and NMNAT2 complexes with heat shock protein 90 (HSP90 (zeige HSP90 ELISA Kits)) to refold aggregated protein substrates.

  2. We confirmed association at NMNAT2 and identified independent SMG7 association with systemic lupus erythematosus in European American and Amerindian/Hispanic ancestries.

  3. NMNAT2 might participate in tumorigenesis of CRC (zeige CALR ELISA Kits).

  4. Knockdown of NMNAT-2 significantly reduces cellular NAD(+) levels and protects cells from p53 (zeige TP53 ELISA Kits)-dependent cell death upon DNA damage, suggesting an important functional role of NMNAT-2 in p53 (zeige TP53 ELISA Kits)-mediated signaling.

  5. Nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) is essential for axon growth and survival.

  6. Overexpression of NMNAT2 in colorectal cancer cells renders them sensitive to Tiazofurin antineoplastic action.

  7. affects tau phosphorylation by regulating PP2A activity

  8. Decreased endogenous NMNAT2 function caused by reduced CREB (zeige CREB1 ELISA Kits) signaling during pathological insults may be one of underlying mechanisms for neuronal death in tauopathies

  9. that overexpression of Nmnat2 in M-cells significantly delayed axon degeneration in vivo

  10. Nmnat2 is a neuronal protein (zeige LRCH1 ELISA Kits) peripherally attached to membranes via palmitoylation and suggest that Nmnat2 is transported to synaptic terminals via an endosomal pathway.

Mouse (Murine) Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) Interaktionspartner

  1. Active nerve degeneration requires SARM1 and MAP kinases, including DLK (zeige DAPK3 ELISA Kits), while the NAD+ synthetic enzyme NMNAT2 prevents degeneration.

  2. nicotinamide mononucleotide adenylyltransferase 2-depletion-dependent degeneration of established axons and restricted extension of developing axons are thus both SARM1 dependent

  3. Data indicate that thioesterases APT1 (zeige FAS ELISA Kits)/APT2 (zeige TAP2 ELISA Kits) depalmitoylate nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) and zDHHC17 is the strongest candidate palmitoyltransferase for NMNAT2.

  4. Complete loss of Nmnat2 leads to a mature but distended bladder in utero and is not compatible with survival. Moderate loss of Nmnat2 has no effect on bladder development, survival, and has only modest effects on bladder function later in life.

  5. Together, our results establish Nmnat2 localisation and turnover as a valuable target for modulating axon degeneration in vivo.

  6. results suggest an essential role for NMNAT2 during axon growth

  7. Nmnat2 activity supports axon survival through a site of action distinct from Nmnat2 transport vesicles.

  8. Nmnat2 is involved in axon development or survival in a mammal.

  9. Decreased endogenous NMNAT2 function caused by reduced CREB (zeige CREB1 ELISA Kits) signaling during pathological insults may be one of underlying mechanisms for neuronal death in tauopathies

  10. Nmnat2 is a neuronal protein (zeige LRCH1 ELISA Kits) peripherally attached to membranes via palmitoylation and suggest that Nmnat2 is transported to synaptic terminals via an endosomal pathway.

NMNAT2 Antigen-Profil

Beschreibung des Gens

This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed\; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit NMNAT2

  • nicotinamide nucleotide adenylyltransferase 2 (nmnat2) Antikörper
  • nicotinamide nucleotide adenylyltransferase 2 (NMNAT2) Antikörper
  • nicotinamide nucleotide adenylyltransferase 2 (Nmnat2) Antikörper
  • AI843915 Antikörper
  • C1orf15 Antikörper
  • D030041I09Rik Antikörper
  • NMNAT2 Antikörper
  • PNAT1 Antikörper
  • PNAT2 Antikörper
  • wu:fj59g01 Antikörper
  • zgc:73048 Antikörper

Bezeichner auf Proteinebene für NMNAT2

NMN adenylyltransferase 2 , naMN adenylyltransferase 1 , nicotinamide mononucleotide adenylyltransferase 2 , nicotinate-nucleotide adenylyltransferase 1 , nicotinamide nucleotide adenylyltransferase 2 , NaMN adenylyltransferase 2 , nicotinate-nucleotide adenylyltransferase 2 , pyridine nucleotide adenylyltransferase 2

GENE ID SPEZIES
336257 Danio rerio
610576 Canis lupus familiaris
743583 Pan troglodytes
771393 Gallus gallus
100124800 Xenopus (Silurana) tropicalis
100172391 Pongo abelii
23057 Homo sapiens
226518 Mus musculus
289095 Rattus norvegicus
511042 Bos taurus
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