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Neutrophil Cytosolic Factor 4 Proteine (NCF4)

Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. Zusätzlich bieten wir Ihnen Neutrophil Cytosolic Factor 4 Antikörper (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
NCF4 17972 P97369
Ratte NCF4 NCF4 500904  
NCF4    
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Top Neutrophil Cytosolic Factor 4 Proteine auf antikoerper-online.de

Showing 2 out of 2 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
682,86 €
Details
HOST_Escherichia coli (E. coli) Maus His tag,T7 tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
725,71 €
Details

NCF4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human

Weitere Proteine zu Neutrophil Cytosolic Factor 4 (NCF4) Interaktionspartnern

Mouse (Murine) Neutrophil Cytosolic Factor 4 (NCF4) Interaktionspartner

  1. p40phox deficiency leads to upregulation of chemokine receptor 1 (zeige CMKLR1 Proteine) and downregulation of fucosyltransferases and sialyltransferases involved in glycan modifications during experimental intestinal inflammation.

  2. cooperation of p40(phox) with p47(phox) for Nox2 (zeige CYBB Proteine)-based NADPH oxidase (zeige NOX1 Proteine) activation during Fcgamma receptor (FcgammaR)-mediated phagocytosis

  3. The defect in Reactive Oxygen Species production and killing of s aureus by p40(phox-/-) neutrophils defines p40(phox) as an essential component in bacterial killing.

  4. p40 (zeige LANCL1 Proteine)(phoxR58A/R58A) embryos do not develop normally but p40 (zeige LANCL1 Proteine)(phoxR58A/-) mice are viable and neutrophils from these animals exhibit significantly reduced oxidase responses compared to those from their p40(phox+/-) siblings.

  5. Class III PI3K Vps34 (zeige PIK3C3 Proteine) is responsible for the synthesis of PtdIns(3)P on phagosomes containing either S aureus or E coli. PtdIns(3)P binding to p40(phox) is important for CD18 (zeige ITGB2 Proteine)-dependent activation oxidase activation in response to S aureus and E coli

  6. p40(phox) is prephosphorylated in resting endothelial cells and can compensate p47(phox) in keeping basal ROS (zeige ROS1 Proteine) production.

Neutrophil Cytosolic Factor 4 (NCF4) Protein Überblick

Protein Überblick

Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. It may be important for the assembly and/or activation of the NADPH-oxidase complex.

Genbezeichner und Symbole assoziert mit NCF4

  • neutrophil cytosolic factor 4 (Ncf4)
  • AI451400 Protein
  • p40phox Protein

Bezeichner auf Proteinebene für NCF4

NCF-4 , neutrophil NADPH oxidase factor 4 , neutrophil cytosol factor 4 , p40-phox

GENE ID SPEZIES
17972 Mus musculus
500904 Rattus norvegicus
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