anti-Neutrophil Cytosolic Factor 1 (NCF1) Antikörper

The protein encoded by NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Maus NCF1 NCF1 17969 Q09014
Anti-Human NCF1 NCF1 653361 P14598
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Weitere Antikörper gegen Neutrophil Cytosolic Factor 1 Interaktionspartner

Mouse (Murine) Neutrophil Cytosolic Factor 1 (NCF1) Interaktionspartner

  1. The authors demonstrated a significant role of the host NADPH oxidase (zeige NOX1 Antikörper) in promoting chronic inflammatory pathology in the oviduct following chlamydial infection.

  2. data partly explains the discrepancy of the phenotypes reported earlier utilizing the Ncf1m1J mice or Ncf1 knockout mice.

  3. Data (including data from studies in transgenic mice) suggest that ability to generate Ncf1-derived superoxide, specifically in CD4 (zeige CD4 Antikörper)-positive T-lymphocytes, is key for development of autoimmune responses in type 1 diabetes.

  4. The Park7 (zeige PARK7 Antikörper) binds to p47(phox), a subunit of the NADPH oxidase (zeige NOX1 Antikörper), to promote NADPH oxidase (zeige NOX1 Antikörper)-dependent production of ROS (zeige ROS1 Antikörper).

  5. p47(phox)-dependent NADPH (zeige FDXR Antikörper) oxidases are a major glomerular source of reactive oxygen species, contributing to kidney injury

  6. p47phox mRNA expression was increased in diet-induced obese (DIO) mice. p47phox suppresses collateral vessel growth after femoral artery ligation in DIO mice.

  7. These findings suggest that a p47(phox)-dependent NAD(P)H (zeige NQO1 Antikörper) oxidase mediates the increase in diaphragm oxidants and contractile dysfunction in chronic heart failure.

  8. The present study provides evidence that augmented EGFRtk impairs vascular function by NADPH oxidase (zeige NOX1 Antikörper)-dependent mechanism. Therefore, EGFRtk and oxidative stress should be potential targets to treat vascular dysfunction in TD2.

  9. NOX2 (zeige CYBB Antikörper)/ROS (zeige ROS1 Antikörper) activity in macrophages signals the development of antigen-specific CD8 (zeige CD8A Antikörper)(+)T cell response.

  10. p47phox plays a critical role in the regulation of adventitial fibroblast proliferation and migration and may be a new therapeutic target for neointimal hyperplasia

Human Neutrophil Cytosolic Factor 1 (NCF1) Interaktionspartner

  1. Decreased and increased copy numbers of NCF1 predispose to and protect against SLE.

  2. Lysophosphatidylcholines prime polymorphonuclear neutrophil through Hck (zeige HCK Antikörper)-dependent activation of PKCdelta (zeige PKCd Antikörper), which stimulates PKCgamma (zeige PRKCG Antikörper), resulting in translocation of phosphorylated p47(phox).

  3. There was an increased frequency of the NCF1-339 T allele in patients with systemic lupus erythematosus. The NCF1-339 T allele reduced extracellular ROS (zeige ROS1 Antikörper) production in neutrophils and led to an increase expression of type 1 interferon (zeige IFNA Antikörper)-regulated genes.

  4. Skeletal muscle protein expression of the NADPH oxidase (zeige NOX1 Antikörper) subunits p22(phox (zeige CYBA Antikörper)), p47(phox), and p67(phox (zeige NCF2 Antikörper)) was increased in obese relative to lean subjects, where p22(phox (zeige CYBA Antikörper)) and p67(phox (zeige NCF2 Antikörper)) expression was attenuated by exercise training in obese subjects.

  5. A novel role for Spns2 (zeige SPNS2 Antikörper) and S1P1 (zeige S1PR1 Antikörper)&2 in the activation of p47(phox) and production of reactive oxygen species involved in hyperoxia-mediated lung injury.

  6. Study provides evidence for a novel PKC-zeta (zeige PRKCZ Antikörper) to p47phox interaction that is required for cell transformation from blebbishields and ROS (zeige ROS1 Antikörper) production in cancer cells.

  7. Overexpression of p47phox is associated with increased migration/metastasis rate in melanoma.

  8. A rare mutation in NCF1 encoding p47phox of the leukocyte NADPH oxidase (zeige NOX1 Antikörper) causes lack of superoxide generation, leads to chronic granulomatous disease and was recently (1200-2300 years ago) introduced into the Kavkazi Jewish population

  9. Data show that diphenylene iodonium (DPI (zeige DSP Antikörper)) and apocynin can reduce hyperoxia-induced reactive oxygen species (ROS (zeige ROS1 Antikörper)) production by decreasing the translocation and level of NADPH Oxidase (zeige NOX1 Antikörper) p47phox.

  10. increased levels of gp91phox (zeige CYBB Antikörper), p47phox and p22phox (zeige CYBA Antikörper) likely account for the interferon-gamma (zeige IFNG Antikörper) mediated enhancement of dimethyl sulfoxide-induced Nox2 (zeige CYBB Antikörper) activity.

Cow (Bovine) Neutrophil Cytosolic Factor 1 (NCF1) Interaktionspartner

  1. Differential Roles of Protein Complexes NOX1 (zeige NOX1 Antikörper)-NOXO1 (zeige NOXO1 Antikörper) and NOX2 (zeige CYBB Antikörper)-p47phox in Mediating Endothelial Redox Responses to Oscillatory and Unidirectional Laminar Shear Stress.

  2. two novel splice variants designed as NCF1-TV1 (retained intron 6) and NCF1-TV2 (retained part of intron 8)encoding two putative truncated proteins (239AA and 283AA). Two splice variants were up-regulated in the mastitis-infected cows' mammary tissues, blood and neutrophils compared with these of healthy cows.

  3. A p47(phox) and Src kinase (zeige CSK Antikörper) activation of peroxide production by Nox2 (zeige CYBB Antikörper) appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C (zeige PKC Antikörper).

Neutrophil Cytosolic Factor 1 (NCF1) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

Genbezeichner und Symbole assoziert mit NCF1

  • neutrophil cytosolic factor 1 (p47phox) Antikörper
  • general transcription factor IIi (GTF2I) Antikörper
  • neutrophil cytosolic factor 1 (Ncf1) Antikörper
  • neutrophil cytosolic factor 1 (NCF1) Antikörper
  • neutrophil cytosolic factor 1 (ncf1) Antikörper
  • cb893 Antikörper
  • Ncf-1 Antikörper
  • NCF1A Antikörper
  • NOXO2 Antikörper
  • p47 Antikörper
  • p47phox Antikörper
  • SH3PXD1A Antikörper

Bezeichner auf Proteinebene für NCF1

neutrophil cytosolic factor 1 , 47 kDa neutrophil oxidase factor , NADPH oxidase subunit (47 kD) , NADPH oxidase subunit (47kDa) , NCF-47K , neutrophil NADPH oxidase factor 1 , neutrophil cytosol factor 1 , p47-phox , 47 kDa autosomal chronic granulomatous disease protein , NADPH oxidase organizer 2 , NCF-1 , SH3 and PX domain-containing protein 1A , neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) , nox organizer 2 , nox-organizing protein 2 , neutrophil cytosolic factor 1 (47kDa, chronic granulomatous disease, autosomal 1) , p47phox

619225 Ciona intestinalis
100227162 Taeniopygia guttata
17969 Mus musculus
653361 Homo sapiens
281345 Bos taurus
378966 Danio rerio
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