anti-Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) Antikörper

NSMAF encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. Zusätzlich bieten wir Ihnen Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Kits (5) und Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NSMAF 8439 Q92636
NSMAF 18201 O35242
NSMAF 353233  
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Top anti-Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Antikörper auf antikoerper-online.de

Showing 10 out of 50 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Maus Kaninchen Unkonjugiert IHC (p), WB NSMAF Antibody (N-term) (ABIN657508) western blot analysis in mouse cerebellum tissue lysates (35 µg/lane). This demonstrates the NSMAF antibody detected the NSMAF protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
418,00 €
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Human Kaninchen Unkonjugiert IHC (p), WB WB Image Western Blot analysis of NSMAF expression in transfected 293T cell line by NSMAF polyclonal antibody. A: Non-transfected lysate. B: NSMAF transfected lysate. 7.5% SDS PAGE antibody diluted at 1:500 IHC-P Image Immunohistochemical analysis of paraffin-embedded human T(gastric cancer) , using NSMAF, antibody at 1:100 dilution. 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
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Human Kaninchen Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
539,00 €
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Human Kaninchen Unkonjugiert IHC (p), IHC, WB Immunohistochemistry-Paraffin: NSMAF Antibody [NBP1-31431] - Paraffin-embedded T(gastric CA), using antibody at 1:100 dilution. Western Blot: NSMAF Antibody [NBP1-31431] - Analysis of NSMAF expression in transfected 293T cell line by NSMAF polyclonal antibody. A: Non-transfected lysate. B: NSMAF transfected lysate. 7.5% SDS PAGE, antibody diluted at 1:500. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Paraformaldehyde-fixed, paraffin embedded Mouse intestines, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with NSMAF Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 minutes and DAB staining. Paraformaldehyde-fixed, paraffin embedded Mouse stomach, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with NSMAF Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 minutes and DAB staining. 100 μL Anmelden zum Anzeigen 18 bis 22 Tage
304,36 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry: NSMAF Antibody [NBP1-84736] - Staining of human colon shows moderate cytoplasmic positivity in glandular cells. Western Blot: NSMAF Antibody [NBP1-84736] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY418576) 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: NSMAF Antibody [NBP1-84737] - Staining of human oral mucosa shows strong nuclear positivity in squamous epithelial cells. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: NSMAF Antibody [NBP1-84735] - Staining of human cell line A-431 shows positivity in nucleoli. Immunohistochemistry-Paraffin: NSMAF Antibody [NBP1-84735] - Staining of human thyroid gland shows strong nuclear and cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
600,64 €
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NSMAF Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Antikörper

  1. Human Polyclonal NSMAF Primary Antibody für WB - ABIN4620368 : OBrien, Gellings, Guo, Barlow, Glembotski, Sabbadini: Factor associated with neutral sphingomyelinase activation and its role in cardiac cell death. in Circulation research 2003 (PubMed)
    Zeige alle 3 Referenzen für 4620368

  2. Human Polyclonal NSMAF Primary Antibody für WB - ABIN265263 : Ségui, Andrieu-Abadie, Adam-Klages, Meilhac, Kreder, Garcia, Bruno, Jaffrézou, Salvayre, Krönke, Levade: CD40 signals apoptosis through FAN-regulated activation of the sphingomyelin-ceramide pathway. in The Journal of biological chemistry 2000 (PubMed)
    Zeige alle 3 Referenzen für 265263

Weitere Antikörper gegen Neutral Sphingomyelinase (N-SMase) Activation Associated Factor Interaktionspartner

Human Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) Interaktionspartner

  1. The interaction of FAN with receptor for activated C-kinase 1 (RACK1 (zeige GNB2L1 Antikörper)) appears to be dependent on the folding of the WD repeats into a secondary structure, because no linear binding motifs are identified in the WD-repeat region of FAN.

  2. sphingolipid activator proteins like domain may stabilize the fold of acid sphingomyelinase (zeige SMPD1 Antikörper)

  3. Regulation of NSMAF by TNF-alpha (zeige TNF Antikörper) involves PRKCD (zeige PKCd Antikörper) in lung epithelial cells.

Mouse (Murine) Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) Interaktionspartner

  1. FAN through promoting melanoma cellular motility and tumour invasiveness is critical for the tumour-promoting action of tumor necrosis factor (zeige TNF Antikörper).

  2. FAN is not implicated in the development of methionine and choline deficient diet-induced non-alcoholic steatohepatitis.

  3. the role of FAN and IL-6 (zeige IL6 Antikörper) in the inflammatory response initiated by endotoxin, implicating TNFalpha (zeige TNF Antikörper)

  4. FAN mediates activation of N-SMase as well as regulation of lysosome size by signaling pathways that operate independent from activation/membrane recruitment of PKC.

  5. The results of this study suggest that PH-mediated plasma membrane targeting of FAN is critically involved in tumor necrosis factor (zeige TNF Antikörper)-induced Cdc42 (zeige CDC42 Antikörper) activation and cytoskeleton reorganization.

  6. This is the first report to demonstrate that TNFalpha (zeige TNF Antikörper)-induced sickness behavior is fully mediated by TNF-R1 (zeige TNFRSF1A Antikörper) and that the adaptor protein FAN is a necessary intracellular intermediate for sickness behavior

  7. these results indicate the involvement of FAN in TNF (zeige TNF Antikörper)-induced gene expression and leukocyte recruitment, contributing to the establishment of the specific immune response.

Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) Antigen-Profil

Protein Überblick

This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit NSMAF

  • protein FAN (EDI_035100) Antikörper
  • neutral sphingomyelinase (N-SMase) activation associated factor (NSMAF) Antikörper
  • neutral sphingomyelinase (N-SMase) activation associated factor (Nsmaf) Antikörper
  • AA959567 Antikörper
  • C630007J05 Antikörper
  • Fan Antikörper

Bezeichner auf Proteinebene für NSMAF

protein FAN , factor associated with N-SMase activation , factor associated with neutral sphingomyelinase activation

GENE ID SPEZIES
5884688 Entamoeba dispar SAW760
8439 Homo sapiens
18201 Mus musculus
353233 Rattus norvegicus
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