Neurogenin 3 (NEUROG3) ELISA Kits

The protein encoded by NEUROG3 is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. Zusätzlich bieten wir Ihnen Neurogenin 3 Antikörper (112) und Neurogenin 3 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
NEUROG3 50674 Q9Y4Z2
NEUROG3 11925 P70661
Anti-Ratte NEUROG3 NEUROG3 60329  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Maus 0.054 ng/mL 0.156-10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
896,09 €
Details
Human
  96 Tests Anmelden zum Anzeigen 25 bis 36 Tage
719,71 €
Details

Weitere ELISA Kits für Neurogenin 3 Interaktionspartner

Xenopus laevis Neurogenin 3 (NEUROG3) Interaktionspartner

  1. These results provide new detail regarding the Ngn3 transcriptional network operating in endocrine progenitor cells to specify a beta (zeige SUCLA2 ELISA Kits) cell phenotype

Human Neurogenin 3 (NEUROG3) Interaktionspartner

  1. Sox9 (zeige SOX9 ELISA Kits) and Ngn3, key transcription factors associated with pancreatic development.

  2. This reviews the expression and function of NEUROG3 in both mouse and human pancreatic development. [Review Article]

  3. Neurogenin3 controls its ability to promote pancreatic endocrine differentiation and to maintain beta cell function in the presence of pro-proliferation cues

  4. Phosphorylation of NEUROG3 links endocrine differentiation to the cell cycle in pancreatic progenitors

  5. Collectively, our results demonstrate that the STAT3 (zeige STAT3 ELISA Kits)(K392R) mutation causes premature endocrine differentiation through direct induction of NEUROG3 expression.

  6. inflammatory cytokine insults stimulate epithelial-to-mesenchymal transition (EMT (zeige ITK ELISA Kits)) as well as the endocrine program in human pancreatic ductal cells via STAT3 (zeige STAT3 ELISA Kits)-dependent NGN3 activation.

  7. ChIP experiments confirmed that Pdx1 (zeige PDX1 ELISA Kits) activates the expression of the downstream transcription factors, Ngn3 and Pax6 (zeige PAX6 ELISA Kits), by combined with the promoter regions of insulin (Insulin (zeige INS ELISA Kits)-P), Ngn3 (Ngn3-P), and Pax6 (Pax6 (zeige PAX6 ELISA Kits)-P).

  8. NGN3 expression in the adult human exocrine pancreas marks a dedifferentiating cell population.

  9. conclude that NEUROG3 is essential for endocrine pancreas development in humans and that as little as 10% NEUROG3 is sufficient for formation of pancreatic endocrine cells

  10. NEUROG3 deficiency produces a rare clinical syndrome characterised by severe malabsorptive diarrhoea from early life and mild diabetes with a variable age of onset.

Mouse (Murine) Neurogenin 3 (NEUROG3) Interaktionspartner

  1. This reviews the expression and function of NEUROG3 in both mouse and human pancreatic development. [Review Article]

  2. Data suggest that hepatocytes can be reprogrammed into insulin-producing cells in vivo by transfection of neurogenin-3, Pdx1, and MafA genes using non-viral hydrodynamics injection; this procedure was used in treatment of streptozotocin diabetes; fasting blood glucose was reduced to normal. (Pdx1 = pancreatic and duodenal homeobox 1; MafA = v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A)

  3. Neurogenin3 controls its ability to promote pancreatic endocrine differentiation and to maintain beta cell function in the presence of pro-proliferation cues

  4. Phosphorylation of NEUROG3 links endocrine differentiation to the cell cycle in pancreatic progenitors

  5. limiting Neurog3 expression dramatically increased the proportional representation of Sox9 (zeige SOX9 ELISA Kits)(+) Neurog3(TA.LO) progenitors, with a doubling of its mitotic index relative to normal Neurog3 expression, suggesting that low Neurog3 expression is a defining feature of this cycling endocrine-biased state

  6. inflammatory cytokine insults stimulate epithelial-to-mesenchymal transition (EMT (zeige ITK ELISA Kits)) as well as the endocrine program in human pancreatic ductal cells via STAT3 (zeige STAT3 ELISA Kits)-dependent NGN3 activation.

  7. Duplication of pre-existing beta-cells is not the sole source of new beta-cells during pregnancy; Ngn3 may be involved in this process.

  8. data demonstrate that HIF1-alpha (zeige HIF1A ELISA Kits) negatively controls beta cell differentiation in vivo by regulating NGN3 expression, and that this effect is mediated by signals from blood vessels.

  9. Data indicate that all neurogenin 3 (Neurog3)-tuberous sclerosis complex 1 (Tsc1 (zeige TSC1 ELISA Kits))-/- mice developed notable adenocarcinoma-like lesions in pancreas starting from the age of 100 days old.

  10. Activation of the developmental pathway neurogenin-3/microRNA-7a regulates cholangiocyte proliferation in response to injury.

Zebrafish Neurogenin 3 (NEUROG3) Interaktionspartner

  1. The control of endocrine cell fate is instead fulfilled by two basic helix-loop-helix factors, Ascl1b and Neurod1 (zeige NEUROD1 ELISA Kits) and NEUROG3 is not the unique pancreatic endocrine cell fate determinant in vertebrates.

  2. Nkx2.2 coordinately activates NeuroD1 with Ngn3 in the endocrine progenitor cell and plays a role in the maintenance of NeuroD1 expression to regulate beta cell function in the mature islet.

Neurogenin 3 (NEUROG3) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).

Genbezeichner und Symbole assoziert mit Neurogenin 3 (NEUROG3) ELISA Kits

  • neurogenin 3 (NEUROG3) Antikörper
  • neurogenin 3 (neurog3) Antikörper
  • neurogenin-3 (Tsp_02556) Antikörper
  • neurogenin 3 (Neurog3) Antikörper
  • neurogenin 3 (NGN3) Antikörper
  • atoh4 Antikörper
  • Atoh5 Antikörper
  • bHLHa7 Antikörper
  • Math4B Antikörper
  • neurog3 Antikörper
  • NGN-3 Antikörper
  • ngn2 Antikörper
  • Ngn3 Antikörper
  • ngn3a Antikörper
  • Relax Antikörper

Bezeichner auf Proteinebene für Neurogenin 3 (NEUROG3) ELISA Kits

neurogenin 3 , neurogenin-3 , class A basic helix-loop-helix protein 7 , protein atonal homolog 5 , NGN-3 , Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B) , atonal homolog 5 , helix-loop-helix protein mATH-4B , transcriptional regulator, Relax , Zath4b , atonal homolog 4

GENE ID SPEZIES
711583 Macaca mulatta
748874 Pan troglodytes
100038294 Xenopus (Silurana) tropicalis
100188927 Xenopus laevis
100461771 Pongo abelii
10898849 Trichinella spiralis
50674 Homo sapiens
11925 Mus musculus
60329 Rattus norvegicus
489022 Canis lupus familiaris
540130 Bos taurus
780450 Ovis aries
114411 Danio rerio
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