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NKX3-2 encodes a member of the NK family of homeobox-containing proteins. Zusätzlich bieten wir Ihnen NK3 Homeobox 2 Antikörper (52) und NK3 Homeobox 2 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
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Bapx1-endothelin 1 (zeige EDN1 ELISA Kits) effector, patterns jaw joint
post-translational modification of Nkx3.2 employing HDAC9 (zeige HDAC9 ELISA Kits)-PIASy (zeige PIAS4 ELISA Kits)-RNF4 (zeige RNF4 ELISA Kits) axis plays a crucial role in controlling chondrocyte viability and hypertrophic maturation during skeletal development in vertebrates.
Bapx1 indicates poor prognosis for gastric cancer patients by promoting tumor migration and invasion via TGF-beta (zeige TGFB1 ELISA Kits)-induced epithelial-mesenchymal transition.
PI3K (zeige PIK3CA ELISA Kits)-mediated suppression of Nkx3.2 in chondrocytes plays a role in the control of cartilage hypertrophy during skeletal development in vertebrates.
Our findings indicate that BAPX-1/NKX-3.2 is a molecular switch that is involved in controlling the hypertrophic phenotype of the postdevelopmental (OA) articular chondrocyte.
Ihh (zeige IHH ELISA Kits)-induced Nkx3.2 degradation requires Wnt5a (zeige WNT5A ELISA Kits), which is capable of triggering Nkx3.2 degradation
Data show that IkappaB kinase (zeige CHUK ELISA Kits) beta (IKKbeta (zeige IKBKB ELISA Kits)) can be activated in the nucleus by Nkx3.2 in the absence of exogenous IKK (zeige CHUK ELISA Kits)-activating signals, allowing constitutive nuclear degradation of IkappaB-alpha (zeige NFKBIA ELISA Kits).
NKX3-2 plays an important role in endochondral ossification of both the axial and appendicular skeleton in humans
Data show that Meox1 (zeige MEOX1 ELISA Kits) activates the Bapx1 promoter in a dose-dependent manner and that this activity is enhanced in the presence of Pax1 (zeige PAX1 ELISA Kits) and/or Pax9 (zeige PAX9 ELISA Kits).
that cartilage-specific and Cre-dependent Nkx3.2 overexpression in mice results in significant postnatal dwarfism in endochondral skeletons
Nkx3.2 promotes primary chondrogenesis by two mechanisms: Direct and Sox9 (zeige SOX9 ELISA Kits)-independent upregulation of Col2a1 (zeige COL2A1 ELISA Kits) transcription and upregulation of Sox9 (zeige SOX9 ELISA Kits) mRNA expression under positive feedback system.
the balance of Pax3 (zeige PAX3 ELISA Kits), Nkx3.2 and Sox9 (zeige SOX9 ELISA Kits) may act as a molecular switch during the chondrogenic differentiation of muscle progenitor cells, which may be important for fracture healing.
These results demonstrated that Nkx3.2-dependent suppression of Runx2 (zeige RUNX2 ELISA Kits) was a crucial factor in hypoxia-dependent maintenance of chondrocyte identity.
Targeted disruption of the Nkx3.2 (Bapx1) gene in mice results in limited defects of chondrocranial bones and the axial skeleton, particularly pronounced in cervical vertebrae.
Pax1 (zeige PAX1 ELISA Kits) and Pax9 (zeige PAX9 ELISA Kits) can transactivate regulatory sequences in the Bapx1 promoter to induce chondrogenic differentiation in the sclerotome.
Nkx3.2 has a critical role in the induction of somitic chondrogenesis
in the Bapx1 mutant embryo, Fgf10 (zeige FGF10 ELISA Kits) expression is downregulated and the dorsal pancreas remains at the midline
This gene encodes a member of the NK family of homeobox-containing proteins. The encoded protein may play a role in skeletal development.
NK3 homeobox 2
, bagpipe homeobox homolog 1
, homeobox protein Nkx-3.2
, bagpipe homeobox protein homolog 1
, NK class homeoprotein Nkx-3.2
, homeobox protein NK-3 homolog B
, bagpipe homeobox gene 1 homolog
, homeodomain protein Nkx-3.2