NIMA (Never in Mitosis Gene A)-Related Kinase 6 Proteine (NEK6)

The protein encoded by NEK6 is a kinase required for progression through the metaphase portion of mitosis. Zusätzlich bieten wir Ihnen NEK6 Antikörper (73) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
NEK6 59126 Q9ES70
NEK6 10783 Q9HC98
NEK6 360161 P59895
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top NEK6 Proteine auf antikoerper-online.de

Showing 10 out of 16 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Baculovirus infected Insect Cells Human Unkonjugiert 5 μg Anmelden zum Anzeigen 6 bis 8 Tage
395,77 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
Hefe Wildschwein His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.701,11 €
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.701,11 €
Details
Hefe Arabidopsis thaliana His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.006,67 €
Details
Insektenzellen Human His-GST   100 μg Anmelden zum Anzeigen 7 bis 8 Tage
1.568,00 €
Details

NEK6 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , , , ,
, , ,
Rat (Rattus)

Weitere Proteine zu NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6) Interaktionspartnern

Mouse (Murine) NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6) Interaktionspartner

  1. NEK6 is overexpressed in various human cancer tissues, and ectopic expression of NEK6 increases tumor promoter-induced transformation of JB6 Cl41 mouse epidermal cells.

  2. During early embryogenesis nek6 is highly expressed in primary giant trophoblast cells. Later in embryogenesis, nek6 is found in ventricular and sub-ventricular regions.

Arabidopsis thaliana NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6) Interaktionspartner

  1. NEK6 (zeige NEK5 Proteine) forms heterodimers with NEK4 and NEK5 to regulate cortical microtubule organization possibly through the phosphorylation of beta-tubulins.

Human NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6) Interaktionspartner

  1. Signaling cascade of the NIMA-related kinases (Neks) Nek6, Nek7, and Nek9 is required for the localization and function of two kinesins essential for cytokinesis, Mklp2 and Kif14 to properly coordinate cytokinesis.

  2. our studies establish NEK6 signaling as a central mechanism mediating castration-resistant prostate cancer

  3. overexpression of PAK1 (zeige PAK1 Proteine), NEK6, AURKA (zeige AURKA Proteine), and AURKB (zeige AURKB Proteine) genes in patients with Colorectal adenomatous polyp and colorectal cancer in the Turkish population.

  4. We found that NEK6-mediated phosphorylation of TPP1 (zeige TPP1 Proteine) Ser255 in G2/M phase regulates the association between telomerase activity and TPP1 (zeige TPP1 Proteine). Furthermore, we found evidence that POT1 (zeige POT1 Proteine) negatively regulates TPP1 (zeige TPP1 Proteine) phosphorylation because the level of Ser255 phosphorylation was elevated when telomeres were elongated by a POT1 (zeige POT1 Proteine) mutant lacking its OB-fold domains

  5. Overexpression of AURKA (zeige AURKA Proteine) and NEK6 genes was significantly more pronounced in Ulcerative colitis patients with more extensive colon involvement

  6. NEK6 suppresses the cell growth arrest induced by TGFbeta (zeige TGFB1 Proteine). Mechanically, NEK6 blocks nuclear translocation of Smad4 (zeige SMAD4 Proteine), which is essential for TGFbeta (zeige TGFB1 Proteine) function.

  7. Nek6 is also a critical signaling molecule that helps prevent cardiac hypertrophy and inhibits the Akt (zeige AKT1 Proteine) signaling pathway.

  8. Nek6 facilitates association of Hsp72 (zeige HSPA1A Proteine) with the mitotic spindle, where it promotes stable K-fiber assembly through recruitment of the ch-TOG-TACC3 (zeige TACC3 Proteine) complex.

  9. Nek6 plays an important role in the premature senescence of cancer cells.

  10. High Nek6 is associated with hepatic cell cancer.

NEK6 Protein Überblick

Protein Überblick

The protein encoded by this gene is a kinase required for progression through the metaphase portion of mitosis. Inhibition of the encoded protein can lead to apoptosis. This protein also can enhance tumorigenesis by suppressing tumor cell senescence. Several transcript variants encoding a few different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit NEK6

  • NIMA (never in mitosis gene a)-related expressed kinase 6 (Nek6)
  • NIMA (never in mitosis gene a)-related kinase 6 (nek6)
  • NIMA (never in mitosis gene a)-related kinase 6 (NEK6)
  • NIMA-related kinase 5 (NEK5)
  • NIMA-related kinase 6 (NEK6)
  • NIMA-related kinase 6 (nek6)
  • NIMA-related kinase 6 (Nek6)
  • 1300007C09Rik Protein
  • ATNEK5 Protein
  • MOE17.17 Protein
  • NIMA-related kinase 5 Protein
  • NIMA-RELATED KINASE5 Protein
  • si:ch211-167p9.4 Protein
  • SID6-1512 Protein

Bezeichner auf Proteinebene für NEK6

NIMA-related expressed kinase 6 , never in mitosis A-related kinase 6 , nimA-related protein kinase 6 , serine/threonine-protein kinase Nek6 , putative serine-threonine protein kinase , NIMA (never in mitosis gene a)-related kinase 6 , protein kinase SID6-1512 , NIMA (never in mitosis gene a)-related expressed kinase 6

GENE ID SPEZIES
59126 Mus musculus
497165 Danio rerio
417101 Gallus gallus
609003 Canis lupus familiaris
100514624 Sus scrofa
515816 Bos taurus
821634 Arabidopsis thaliana
10783 Homo sapiens
380346 Xenopus laevis
360161 Rattus norvegicus
Ausgewählte Anbieter für NEK6 Proteine (NEK6)
Haben Sie etwas anderes gesucht?