anti-NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) (NFU1) Antikörper

NFU1 encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. Zusätzlich bieten wir Ihnen NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NFU1 27247 Q9UMS0
NFU1 56748 Q9QZ23
NFU1    
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Top anti-NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) Antikörper auf antikoerper-online.de

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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of NFU1 staining in mouse brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the an Western blot analysis of NFU1 expression in SW480 (A), mouse liver (B), mouse heart (C), rat liver (D), rat heart (E) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
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Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) Antibody [NBP2-48647] - Staining of human vulva/anal skin shows strong cytoplasmic positivity in epidermal cells. Immunocytochemistry/Immunofluorescence: NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) Antibody [NBP2-48647] - Analysis of human cell line U-2 OS shows positivity in cytoplasm & nucleus but excluded from the nucleoli. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
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NFU1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human ,


Mouse (Murine)


Rat (Rattus)


Weitere Antikörper gegen NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) Interaktionspartner

Human NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) (NFU1) Interaktionspartner

  1. a direct role for human Nfu in the process of [2Fe-2S] cluster trafficking and delivery

  2. Analysis of protein stability and oligomeric state demonstrates that the Gly208Cys mutant increases the propensity to dimerize and perturbs the secondary structure composition. These changes appear to underlie the severely decreased ability of mutant NFU1 to accept an Fe/S cluster from physiologically relevant sources.

  3. Study used NMR spectroscopy and small-angle X-ray scattering data to determine the 3D structure of human mitochondrial NFU1 in its apo (zeige C9orf3 Antikörper)- and iron-sulfur cluster-containing holo-form. Apo (zeige C9orf3 Antikörper)- NFU1 is monomeric, whereas holo-NFU1 consists of a trimer of three [4Fe-4S] cluster-linked dimers.

  4. a leaky splicing regulation due to a splice site mutation (c.545+5G>A) that produces small amounts of wild type NFU1 mRNA that might result in enough protein to partially lipoylate and restore the activity of lipoic acid-dependent enzymes and the assembly and activity of complex I.

  5. A new NFU1 mutation is reported in a patient presenting with a milder phenotype characterized by a later onset, a slowly progressive spastic paraparesis with relapsing-remitting episodes, mild cognitive impairment and a long survival.

  6. This study provides new insights into the molecular bases of NFU1 disease.

  7. A fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins

  8. Mutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 (zeige BOLA3 Antikörper) cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes [case report]

  9. Analyses of genomic DNA, transcripts, and translation products indicate that alternative splicing of a common pre-mRNA results in synthesis of two Nfu isoforms with distinct subcellular localizations.

  10. Laforin (zeige EPM2A Antikörper) interacts with HIRIP5.

NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) (NFU1) Antigen-Profil

Protein Überblick

This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Genbezeichner und Symbole assoziert mit NFU1

  • NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) (NFU1) Antikörper
  • NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) (Nfu1) Antikörper
  • 0610006G17Rik Antikörper
  • CGI-33 Antikörper
  • HIRIP Antikörper
  • Hirip5 Antikörper
  • MMDS1 Antikörper
  • Nfu Antikörper
  • NifU Antikörper
  • NIFUC Antikörper

Bezeichner auf Proteinebene für NFU1

HIRA-interacting protein 5 , NFU1 iron-sulfur cluster scaffold homolog, mitochondrial , NifU-like C-terminal domain containing , iron-sulfur cluster scaffold protein , histone cell cycle regulation defective interacting protein 5 , mHIRIP5

GENE ID SPEZIES
27247 Homo sapiens
56748 Mus musculus
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