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NDRG2 is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. Zusätzlich bieten wir Ihnen NDRG2 Proteine (24) und NDRG2 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 96 products:
Human Monoclonal NDRG2 Primary Antibody für ELISA, WB - ABIN566107
Shen, Zhao, Wang, Ji, Liu, Liu, Che, Lin, Li, Zhang, Yao: Immunohistochemical detection of Ndrg2 in the mouse nervous system. in Neuroreport 2008
Show all 16 Pubmed References
Human Polyclonal NDRG2 Primary Antibody für ICC, IF - ABIN4338340
Tepel, Roerig, Wolter, Gutmann, Perry, Reifenberger, Riemenschneider: Frequent promoter hypermethylation and transcriptional downregulation of the NDRG2 gene at 14q11.2 in primary glioblastoma. in International journal of cancer 2008
Show all 5 Pubmed References
Human Polyclonal NDRG2 Primary Antibody für ELISA, WB - ABIN528174
Araya-Callís, Hiemke, Abumaria, Flugge: Chronic psychosocial stress and citalopram modulate the expression of the glial proteins GFAP and NDRG2 in the hippocampus. in Psychopharmacology 2012
Show all 2 Pubmed References
Human Polyclonal NDRG2 Primary Antibody für ELISA, WB - ABIN4338339
Shi, Li, Li, Chen, Wang, Xu, Zhang, Jin, Zhang, Zhao, Song, Feng, Feng, Shen, Yao, Zhao: Expression of NDRG2 in esophageal squamous cell carcinoma. in Cancer science 2010
Human Polyclonal NDRG2 Primary Antibody für WB - ABIN528175
Wang, Zhong, Li, Peng, Kinden, Liang, Li, Shi, Liu, Wang, Xiong: Electroacupuncture attenuates reference memory impairment associated with astrocytic NDRG2 suppression in APP/PS1 transgenic mice. in Molecular neurobiology 2014
Our results show how NDRG2 expression serves as a critical determinant of the invasive and metastatic capacity of oral squamous cell carcinoma (OSCC)
Using double knockout of NDR1 (zeige STK38 Antikörper) and 2 shows that NDRs acted downstream of MST1 (zeige MST1 Antikörper) to mediate the egress of mature thymocytes from the thymus, as well as the interstitial migration of naive T cells within popliteal lymph nodes.
The expression level of NDRG2 has a causal influence on mood-related phenotypes.
Ndr1 (zeige STK38 Antikörper)/2-double null embryos show defects in somitogenesis and cardiac looping, which reveals their essential functions and shows that the NDR (zeige STK38 Antikörper) kinases are critically required during the early phase of organogenesis
Taken together, our results suggest that the expression of NDRG2 potentially inhibits osteoclast differentiation and plays a role in modulating the signal transduction pathway responsible for osteoclastogenesis.
NDRG2 is associated with decidualization during early pregnancy.
NDRG2 accumulated in skeletal muscle and myoblasts in the absence of TRIM32 (zeige TRIM32 Antikörper). NDRG2 overexpression in myoblasts led to reduced cell proliferation and delayed cell cycle withdrawal during differentiation.
Electroacupuncture administration can alleviate reference memory deficits and suppress N-myc downstream-regulated gene 2 upregulation in an AD transgenic mouse model
Rassf5 (zeige RASSF5 Antikörper) and Ndr1 (zeige STK38 Antikörper) or Ndr2 (zeige STK38L Antikörper) kinases regulate neuronal polarity through Par3 (zeige F2RL2 Antikörper) phosphorylation.
Ndrg2 plays a key role in reactive astrogliosis after cortical stab injury through a mechanism involving the positive regulation of IL-6 (zeige IL6 Antikörper)/STAT3 (zeige STAT3 Antikörper) signaling
putative tumor suppressive function of NDRG2 may be confined to luminal- and basal B-type breast cancers
Overexpression of NDRG2 can inhibit the proliferation.
present results suggest that hypermethylation in promoter around exon 2 is functioning as essential factors of NDRG2 silencing in gastrointestinal cancers
NDRG2 overexpression significantly reduced hepatoma cell proliferation and enhanced cell apoptosis under glucose limitation. Moreover, NDRG2 overexpression aggravated energy imbalance and oxidative stress by decreasing the intracellular ATP and NADPH (zeige NQO1 Antikörper) generation and increasing ROS (zeige ROS1 Antikörper) levels.
The methylation status of the NDRG2 promoter in PBMCs is a potential noninvasive biomarker to predict the severity of liver fibrosis.
Data show that downregulation of NDRG2 may play an important role in advanced hepatoblastomas.
Study shows that NDRG2 was significantly down-regulated in glioblastomas (GBM) and seems to play a role in GBM prognosis. The low expression of NDRG2 at the mRNA level leads to a longer progression-free survival independent of methylation status.
Stuidies indicate the potential of N-myc downstream-regulated gene 2 (NDRG2) as a therapeutic target for cancer.
NDRG2 overexpression enhanced sodium/iodide symporter (zeige SLC5A5 PLURAL_@12224@) level in thyroid tumor cells and increased their iodine uptake in vitro.
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
, NDRG family member 2
, N-myc downstream-regulated gene 2
, N-myc downstream regulated 2
, N-myc downstream-regulated gene 2 protein
, protein Ndr2
, N-myc downstream regulator 2
, NDR1-related protein NDR2
, cytoplasmic protein Ndr1
, syld709613 protein
, N-myc downstream regulated gene 2
, NDRG1-related protein
, antidepressant-related protein ADRG123
, N-Myc downstream regulated gene 2