NAD(P)H Dehydrogenase, Quinone 1 Proteine (NQO1)

NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. Zusätzlich bieten wir Ihnen NQO1 Antikörper (221) und NQO1 Kits (30) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
NQO1 1728 P15559
NQO1 24314 P05982
NQO1 18104 Q64669
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Top NQO1 Proteine auf antikoerper-online.de

Showing 10 out of 16 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
555,24 €
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HOST_Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
954,50 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.584,12 €
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HOST_Escherichia coli (E. coli) Human His tag   1 mg Anmelden zum Anzeigen 6 bis 8 Tage
5.531,43 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
657,49 €
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HOST_Escherichia coli (E. coli) Human S tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
685,71 €
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NQO1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, , ,
Rat (Rattus) ,
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Mouse (Murine)
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Am meisten referenzierte NQO1 Proteine

  1. Human NQO1 Protein expressed in Escherichia coli (E. coli) - ABIN668043 : Jaiswal, McBride, Adesnik, Nebert: Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase. cDNA sequence and localization of gene to chromosome 16. in The Journal of biological chemistry 1988 (PubMed)
    Zeige alle 2 Referenzen für 668043

Weitere Proteine zu NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Interaktionspartnern

Zebrafish NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Interaktionspartner

  1. Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (zeige AKT1 Proteine) and JNK (zeige MAPK8 Proteine)/Nrf2 (zeige NFE2L2 Proteine)/NQO1 pathway.

Human NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Interaktionspartner

  1. Results show that H80R causes a population shift in the conformational ensemble of apo (zeige C9orf3 Proteine)-P187S, remodelling the structure and dynamics of the FAD (zeige BRCA2 Proteine)-binding site and reducing the energetic penalization arising from the equilibrium between apo (zeige C9orf3 Proteine)- and holo-states.

  2. The C609T polymorphism within NQO1 is independently associated with CAD in women, but no association was observed in whole study population or in men.

  3. This study suggests that HNC (zeige MMP8 Proteine) samples should be screened for NQO1 expression to identify patients that will likely benefit from combined therapy with beta-lap and IR.

  4. The results indicate that NQO1*2 genotype may increase susceptibility to DN in north Indian subjects with T2DM.

  5. Thus, our findings indicated that NQO1 could stabilize Herp (zeige HERPUD1 Proteine) protein expression via indirect regulation of synoviolin.

  6. NQO1 and GCLC (zeige GCLC Proteine) were both functionally sufficient to autonomously confer a tamoxifen-resistant metabolic phenotype, characterized by i) increased mitochondrial biogenesis, ii) increased ATP production and iii) reduced glutathione levels.

  7. NQO1 induces hepatocellular carcinoma cell apoptosis and proliferation inhibition through the AMPK/PGC-1alpha pathway.

  8. the expression of NRF2 (zeige GABPA Proteine), KEAP1 (zeige KEAP1 Proteine), NQO-1 and HO-1 (zeige HMOX1 Proteine) are increased significantly in advanced laryngeal squamous cell carcinoma, compared with the adjacent normal mucosa. Remarkable relevance exists between high expression of KEAP1 (zeige KEAP1 Proteine), NQO-1, HO-1 (zeige HMOX1 Proteine) and nuclear NRF2 (zeige GABPA Proteine). their expression levels were independent of age, tumor stage (clinical stage III and IV), tumor size and lymph node metastasis.

  9. (i) melatonin counteracted UVR-induced alterations in the ATP synthesis and reduced free radical formation; (ii) melatonin induced the translocation of Nrf2 (zeige GABPA Proteine) transcription factor from the cytosol into the nucleus resulting in, (iii) melatonin enhanced gene expression of phase-2 antioxidative enzymes including gamma-glutamylcysteine synthetase (zeige GCLC Proteine) (gamma-GCS (zeige GCLC Proteine)), heme oxygenase-1 (HO-1 (zeige HMOX1 Proteine)), and NADPH: quinone dehydrogenase-1 (NQO1...

  10. Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (zeige AKT1 Proteine) and JNK (zeige MAPK8 Proteine)/Nrf2 (zeige GABPA Proteine)/NQO1 pathway.

Mouse (Murine) NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Interaktionspartner

  1. NQO1 and autophagy participate in a protective role in cisplatin injury.

  2. A significant increase was found in Nrf2 (zeige NFE2L2 Proteine)-ARE activity after partial hepatectomy (PHx). The signal maximum was recorded on the third day after PHx. Significantly more hepatocytes were positive for Nrf2 (zeige NFE2L2 Proteine) and HO-1 (zeige HMOX1 Proteine) on the third postoperative day compared with baseline levels. The mRNA expression of HO-1 (zeige HMOX1 Proteine) and NQO1 were significantly increased on day 3.

  3. Miroestrol restored hepatic NQO1 expression in beta-naphthoflavone-treated mice.

  4. previous and present results collectively show that NQO1 is involved in the formation of tight junctions in the small intestine, and that defects in NQO1 enhance C. difficile toxin A-induced acute inflammatory responses, presumably via the loss of epithelial cell tight junctions

  5. NQO1 plays a critical role in protection against energy depletion in acetaminophen-induced liver injury, and is associated with improvement of mitochondrial dysfunction

  6. The present results demonstrate that exacerbated cisplatin-induced nephrotoxicity under the NQO1-knockout condition was accompanied by the reduced expression of MRN complex proteins, ATM (zeige ATM Proteine), PARP1 (zeige PARP1 Proteine), and Sirt1 (zeige SIRT1 Proteine).

  7. Taken together, these data suggest that EEEC attenuates oxidative stress by activating Nrf2 (zeige NFE2L2 Proteine)-mediated HO-1 (zeige HMOX1 Proteine) and inducing NQO-1 via the activation of MAPK (zeige MAPK1 Proteine) signaling pathways.

  8. We defined the basal and butylated hydroxyanisole induced expression patterns of Nqo1, AKR1B8, and Ho-1 (zeige HMOX1 Proteine) in the liver and small intestine of C57BL/6 mice.

  9. The colons of NQO1-KO mice also showed high levels of reactive oxygen species (ROS (zeige ROS1 Proteine)) and histone deacetylase (HDAC (zeige HDAC1 Proteine)) activity, which are known to affect transcriptional regulation.

  10. the induction of cellular NAD(+) levels using beta-lapachone (beta-Lap), whose intracellular target is NQO1, prevents the toxic effects of cisplatin through the regulation of PARP-1 (zeige PARP1 Proteine) and SIRT1 (zeige SIRT1 Proteine) activity.

Pig (Porcine) NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Interaktionspartner

  1. The obtained data convincingly showed that porcine NADPH-d cells may produce nitric oxide.

  2. Immunoreactivity of eNOS (zeige NOS3 Proteine) was similar to NADPH-d staining. Clear iNOS (zeige NOS2 Proteine) immunoreactivity was detected in the luminal epithelium, endometrial stroma and individual endometrial glands.

Cow (Bovine) NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Interaktionspartner

  1. NQO1 expression was increased in the ruminal papillae of more efficient low residual feed intake (RFI (zeige RNF34 Proteine)) animals compared to the high RFI (zeige RNF34 Proteine) animals

NQO1 Protein Überblick

Protein Überblick

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Genbezeichner und Symbole assoziert mit NQO1

  • NAD(P)H dehydrogenase, quinone 1 (nqo1)
  • NAD(P)H dehydrogenase, quinone 1 (NQO1)
  • NAD(P)H dehydrogenase, quinone 1 (Bpet2092)
  • NAD(P)H dehydrogenase, quinone 1 (Nqo1)
  • AV001255 Protein
  • DHQU Protein
  • Dia4 Protein
  • Dtd Protein
  • NADPH-d Protein
  • Nmo-1 Protein
  • Nmo1 Protein
  • Nmor1 Protein
  • NMORI Protein
  • nqo1 Protein
  • Ox-1 Protein
  • Ox1 Protein
  • Qr1 Protein
  • wu:fb63c10 Protein
  • zgc:77191 Protein

Bezeichner auf Proteinebene für NQO1

NAD(P)H dehydrogenase [quinone] 1 , NAD(P)H menadione oxidoreductase 1, dioxin-inducible , NAD(P)H dehydrogenase, quinone 1 , DT-diaphorase , DTD , NAD(P)H:quinone oxidoreductase 1 , QR1 , azoreductase , menadione reductase , phylloquinone reductase , quinone reductase 1 , nad(p)h dehydrogenase (quinone) 1 , NAD(P)H:Quinone acceptor oxidoreductase type 1 , NAD(P)H:menadione oxidoreductase 1 , NAD(P)H:quinone oxireductase , diaphorase (NADH/NADPH) (cytochrome b-5 reductase) , diaphorase-4 , dioxin-inducible 1 , Diaphorase (NADH/NADPH) , NAD(P)H:menadione oxidoreductase , NAD(P)H dehydrogenase (quinone) , NAD(P)H menadione oxidoreductase 1, dioxin inducible , diaphorase 4 (NADH/NADPH) , nicotinamide adenine dinucleotide phosphate diaphorase , diaphorase 4 , NAD(P)H: quinone oxidoreductase 1

GENE ID SPEZIES
322506 Danio rerio
468012 Pan troglodytes
549222 Xenopus (Silurana) tropicalis
705635 Macaca mulatta
769737 Gallus gallus
4606922 Azoarcus sp. BH72
5818094 Bordetella petrii DSM 12804
100049751 Xenopus laevis
100172039 Pongo abelii
100528193 Ictalurus punctatus
1728 Homo sapiens
610935 Canis lupus familiaris
24314 Rattus norvegicus
18104 Mus musculus
100286873 Sus scrofa
519632 Bos taurus
100135582 Cavia porcellus
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