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anti-Myostatin (MSTN) Antikörper

The protein encoded by MSTN is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. Zusätzlich bieten wir Ihnen Myostatin Kits (75) und Myostatin Proteine (70) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MSTN 2660 O14793
MSTN 17700 O08689
MSTN 29152 O35312
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Top anti-Myostatin Antikörper auf antikoerper-online.de

Showing 10 out of 232 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Details
Human Maus Unkonjugiert ELISA, WB Figure 1: Western blot analysis using Myostatin mouse mAb against truncated Myostatin-His recombinant protein (1) . 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
399,32 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-GDF8 N-term Pab (ABIN388821) in mouse liver tissue lysate. GDF8 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with GDF8 antibody (N-term )(ABIN388821), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Huhn Unkonjugiert EIA   50 μg Anmelden zum Anzeigen 8 bis 10 Tage
319,00 €
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Human Maus Unkonjugiert WB 0.1 mL Anmelden zum Anzeigen 8 bis 10 Tage
396,00 €
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Human Kaninchen Unkonjugiert EIA, IHC (p) 50 μg Anmelden zum Anzeigen 8 bis 10 Tage
379,50 €
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Human Maus Unkonjugiert IHC (p), ELISA, WB Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Human Maus Unkonjugiert EIA, IHC (p), WB 50 μL Anmelden zum Anzeigen 8 bis 10 Tage
517,00 €
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Human Rind (Kuh) Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
289,14 €
Details
Human Maus Unkonjugiert IHC, WB Western Blot staining of a control protein  Lane 1: Recombinant protein 10 ng/Lane, Reducing  Lane 2: Recombinant protein 1 ng/Lane, Reducing  Recombinant protein Myostatin Propeptide Human (E.coli, Tag free) was subjected to SDS PAGE followed by Western Blot with ABIN2532791 (Myostatin Propeptide Human, , Mouse Monoclonal Antibody, Clone: 4B9) at a concentration of 1 μg/ml. Stained with DAB. Immunohistochemical staining of formalin-fixed paraffin-embedded human sceletal muscle using this product at a concentration of 2 µg/mL (original magnification, 20x (left) and 40x (right)). Detection DAB. Positive cytoplasmic staining in myocytes. 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
314,29 €
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MSTN Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Myostatin Antikörper

  1. Human Polyclonal MSTN Primary Antibody für EIA - ABIN115510 : Wolfman, McPherron, Pappano, Davies, Song, Tomkinson, Wright, Zhao, Sebald, Greenspan, Lee: Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Zeige alle 4 Referenzen für ABIN115510

  2. Human Polyclonal MSTN Primary Antibody für WB - ABIN108525 : McPherron AC,Lee SJ: Double muscling in cattle due to mutations in the myostatin gene. in Proc Natl Acad Sci U S A 1997 (PubMed)
    Zeige alle 3 Referenzen für ABIN108525

  3. Human Polyclonal MSTN Primary Antibody für EIA, IHC (p) - ABIN357462 : Hamrick, McPherron, Lovejoy: Bone mineral content and density in the humerus of adult myostatin-deficient mice. in Calcified tissue international 2002 (PubMed)
    Zeige alle 3 Referenzen für ABIN357462

  4. Human Monoclonal MSTN Primary Antibody für ELISA, WB - ABIN969306 : Awano, Takeshima, Okizuka, Saiki, Yagi, Matsuo: Wide ranges of serum myostatin concentrations in Duchenne muscular dystrophy patients. in Clinica chimica acta; international journal of clinical chemistry 2008 (PubMed)
    Zeige alle 2 Referenzen für ABIN969306

  5. Human Monoclonal MSTN Primary Antibody für WB - ABIN1108369 : Wójcik, Nogalska, Engel, Askanas: Myostatin and its precursor protein are increased in the skeletal muscle of patients with Type-II muscle fibre atrophy. in Folia morphologica 2008 (PubMed)

Weitere Antikörper gegen Myostatin Interaktionspartner

Zebrafish Myostatin (MSTN) Interaktionspartner

  1. improving muscle growth in a fish species by mixing a classical strategy, such as compensatory growth, and a biotechnological approach, such as the use of recombinant proteins for inhibiting the biological actions of MSTN(Myostatin)

  2. the expression of myostatin during development and the effects of its knock-down on various genes such as muscle regulatory transcription factors (MRFs), muscle-specific (zeige EIF3K Antikörper) proteins (MSP (zeige MST1 Antikörper)), and insulin (zeige INS Antikörper)-like growth factors (IGFs).

  3. Epistatic analyses suggest a possible genetic interaction between Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) and Myostatin in regulation of slow and fast twitch muscle myofibrillogenesis

Medaka Myostatin (MSTN) Interaktionspartner

  1. TALENs-mediated gene disruption of myostatin produces a larger phenotype of medaka with an apparently compromised immune system

  2. Findings suggest that myostatin (MSTN) function is required for regulating the appropriate growth of skeletal muscle in medaka

Human Myostatin (MSTN) Interaktionspartner

  1. Multivariate regression analysis revealed that myostatin levels correlated significantly with tricuspid annular plane systolic excursion values and right ventricle myocardial performance index among the study patients

  2. Study measured circulating myostatin levels in seven inherited muscle diseases using an immunoaffinity LC-MS/MS approach, found significantly lower serum myostatin concentrations in numerous muscle disease patient populations and the associations with clinical measurements suggests the potential utility of myostatin as a biomarker of genetic muscle disease progression

  3. data indicated that serum myostatin concentration did not correlate with muscle and bone mass in postmenopausal women

  4. Myostatin mRNA expression in skeletal muscle was significantly reduced compared with pre-exercise values at all time points with no difference between exercise intensity.

  5. Low expression of serum MSTN is associated with Cachexia Prevention in Patients with Medullary Thyroid Cancer.

  6. Myostatin was differentially expressed in the muscle and adipose tissue in relation to physical activity and dysglycaemia

  7. Our results suggest that serum levels of myostatin and irisin (zeige FNDC5 Antikörper) are related in patients with type 2 diabetes

  8. Matrix metalloproteinase 14 (zeige MMP14 Antikörper) was highly expressed in uterine leiomyoma and correlated with myostatin and activin A (zeige INHBA Antikörper) mRNA expression. Moreover, MMP14 (zeige MMP14 Antikörper) and myostatin mRNA expression correlated significantly and directly with the intensity of dysmenorrhea.

  9. A synthetic peptide corresponding to this decorin (zeige DCN Antikörper) region dose-dependently inhibited the response to myostatin in cardiomyocytes

  10. Findings suggest that GDF8 and CTGF (zeige CTGF Antikörper) may play critical roles in the regulation of proliferative events in human granulosa cells.

Mouse (Murine) Myostatin (MSTN) Interaktionspartner

  1. In this model, increased LTBP4 (zeige LTBP4 Antikörper) led to greater muscle mass with proportionally increased strength, and decreased fibrosis. The increase in muscle mass and reduction in fibrosis were similar to what occurs when myostatin, a related TGFbeta (zeige TGFB1 Antikörper) family member and negative regulator of muscle mass, was deleted in mdx (zeige DMD Antikörper) mice

  2. myostatin dysfunction impairs adaptation of the soleus muscle to high functional demands.

  3. Evidences indicate that the suppression of MSTN cause to increase the regenerative potential of injured soleus muscle via the increase in the population of muscle satellite cells regardless of unloading conditions.

  4. A role for Nfix (zeige MLZE Antikörper) in postnatal skeletal muscle development and regeneration and Myostatin gene expression regulation.

  5. Myostatin deletion specifically affects skeletal muscle mitochondrial function and redox status. Decreased mitochondrial function and oxidative markers persisted in aged mstn KO mice. However, muscle hypertrophy and the redox status related to this genotype appeared as beneficial side effects attenuating the age effect, as metabolic changes become less pronounced in comparison with WT mice.

  6. A synthetic peptide corresponding to this decorin (zeige DCN Antikörper) region dose-dependently inhibited the response to myostatin in cardiomyocytes

  7. myostatin may play an important role in maintaining ankle and wrist joint health.

  8. Agouti-related peptide (AgRP (zeige AGRP Antikörper)) neuron activation acutely reprograms gene expression in BAT (zeige BAAT Antikörper) toward a myogenic signature, including increased expression of myostatin. Interference with myostatin activity improves insulin (zeige INS Antikörper) sensitivity that was impaired by AgRP (zeige AGRP Antikörper) neurons activation.

  9. Increased expression of myostatin in heart muscle cells caused interstitial fibrosis via activation of the TAK-1 (zeige NR2C2 Antikörper)-MKK3 (zeige MAP2K3 Antikörper)/6-p38 (zeige CRK Antikörper) signaling pathway

  10. study is the first to report an in vivo association between vitamin D, myostatin, and the regulation of muscle mass

Pig (Porcine) Myostatin (MSTN) Interaktionspartner

  1. These results indicate that myostatin mediates maternal low protein diet-induced growth retardation, through epigenetic regulation involving FoxO3 (zeige FOXO3 Antikörper) and glucocorticoid receptor (zeige NR3C1 Antikörper) binding to its promoter.

  2. Loss of MSTN increases muscle mass in pigs, which may help increase pork production for consumption in the future.

  3. Data show that the protein level of The protein level of myostatin (MSTN) was decreased in the mutant cloned pigs compared with the wild-type controls.

  4. Single nucleotide polymorphisms in the MYOD1 (zeige MYOD1 Antikörper) and GDF8 genes are associated with genetic transcription during myogenesis in pigs.

  5. The level of myostatin inversely correlated with miR (zeige MYLIP Antikörper)-27a in fat and heart of pigs and also in proliferating porcine myoblasts. Overexpression of miR (zeige MYLIP Antikörper)-27a in porcine myoblasts promoted cell proliferation by reducing the expression of myostatin.

  6. MSTN g.435G>A and g.447A>G affected carcass traits in pigs

  7. The genotypes of MSTN g.435G > A and g.447A > G SNPs in Duroc pigs were studied. The 435GG/447AA (zeige COL16A1 Antikörper) individually had significantly higher average daily gain, body weight at 70 d and 150 d , and a lower age at 110 kg than 435AA/447GG individuals.

  8. Porcine MSTN could be upregulated by isobutyl-1-methylxanthine , MyoD (zeige MYOD1 Antikörper), and PPARgamma (zeige PPARG Antikörper) but downregulated by C/EBPalpha (zeige CEBPA Antikörper) and C/EBPbeta (zeige CEBPB Antikörper).

  9. a vital enhancer region was identified between nucleotides -218 and -137 in promoter region of porcine myostatin

  10. It was concluded that myostatin is a factor broadly expressed in the internal organs and muscle tissues of pigs.

Cow (Bovine) Myostatin (MSTN) Interaktionspartner

  1. Data indicate that the the promoter trap vector PIII-myostatin could knock out the bovine myostatin gene.

  2. The effects of myostatin and myogenic factor 5 (zeige MYF5 Antikörper) polymorphisms on growth and muscle traits of Marchigiana breed were assessed.

  3. we demonstrate zygote injection of TALEN mRNA can also produce gene-edited cattle and sheep. In both species we have targeted the myostatin (MSTN) gene.

  4. proof-of-concept study is the first to produce MSTN mutations in cattle, and may allow the development of genetically modified strains of double-muscled cattle.

  5. Mutations in the leader peptide of the bovine myostatin gene effectively promote the proliferation of bovine fibroblast cells.

  6. there were 18 SNPs identified in the Qinchuan cattle promoter region compared with those of other cattle compared to the Red Angus cattle myostatin promoter region.

  7. A 3-way interaction of myostatin genotype (MG), season, and trigonometric function periodicities of 24 h and 12 h indicate that a genotype x environment interaction exists for MG.

  8. These results show for the first time that myostatin regulates the differential expression of chemokines in skeletal muscle cells.

  9. bovine myostatin is a specific target of miR (zeige MYLIP Antikörper)-27b and that miRNAs contribute to explain additive phenotypic hypertrophy in Piedmontese cattle selected for the MSTN gene mutation

  10. Mutations in the myostatin gene, responsible for the double muscling condition in cattle, were targeted to estimate the time since the most recent common ancestor. Each myostatin allele had a recent common ancestor (<400 years ago).

Goat Myostatin (MSTN) Interaktionspartner

  1. The reduced expression of myostatin gene was achieved and measured in clonal fibroblast cells by real-time PCR.

  2. This study also suggests the importance of siRNA-mediated knockdown of MSTN as a potential alternative to increase muscle mass and meat production.

  3. A study of the MSTN 5' upstream region and investigation of 5'UTR (zeige UTS2R Antikörper) TTTTA deletion was carried out in seven different Indian goat breeds. An 1181 bp fragment of 5' upstream region of MSTN gene was PCR amplified, cloned, and sequenced.

  4. myostatin plays a negative role in regulating the expression of adipogenesis related genes in goat fetal fibroblasts.

  5. Polymorphisms of myostatin gene as markers associated with growth in Boer goats.

Horse (Equine) Myostatin (MSTN) Interaktionspartner

  1. The effect of an Equine Repetitive Element 1 insertion in the promoter of the myostatin gene, which is involved in muscle development, was also investigated.

  2. Myostatin mRNA but not protein was increased in skeletal muscle of obese compared with lean animals. Myostatin mRNA was increased in crest fat of obese animals and protein was undetectable. Serum myostatin was higher in obese than lean animals.

  3. The tissue-specific presence of myostatin, the moystatin receptor (activin receptor IIB (zeige ACVR2B Antikörper), ActRIIB (zeige ACVR2B Antikörper)), follistatin (zeige FST Antikörper) and perilipin (zeige PLIN1 Antikörper), genes and proteins across a range of equine tissues, were examined.

  4. The candidate for racing performance genomic region contained eight genes annotated by ENSEMBL, including the myostatin gene (MSTN).

  5. Polymorphisms of the MSTN promoter region in 5 horse breeds in Poland are reported.

  6. significant association observed between genotype and mRNA abundance for untrained horses with the C/C cohort having highest MSTN mRNA levels,T/T group lowest levels and C/T group intermediate levels; following training there was significant decrease in MSTN mRNA which was most apparent for the C/C cohort

  7. Exon 2 of the MSTN gene, which encodes part of the TGF-beta (zeige TGFB1 Antikörper) pro-peptide, was sequenced in 332 horses of 20 different breeds and compared with the horse MSTN gene sequence deposited in GenBank. The sequences obtained revealed the presence of 11 haplotypes represented by 10 variable nucleotide mutations, eight of them corresponding to amino acid sequence changes.

  8. Variation at the MSTN gene influences speed in Thoroughbred horses.

  9. This study demonstrates that the g.66493737C>T single nucleotide polymorphism in MSTN provides the most powerful genetic marker for prediction of race distance aptitude in Thoroughbreds.

  10. Characterized the horse (Equus caballus) MSTN gene and identified and analysed single nucleotide polymorphisms (SNPs) in breeds of different morphological types.

Rabbit Myostatin (MSTN) Interaktionspartner

  1. Alignment of sequence data with the GenBank sequence of the rabbit MSTN gene identified three single nucleotide polymorphisms (SNPs). Significant linkage was found between the novel SNP c.373+234G>A and nine carcass composition traits.

  2. These results suggest that the mutations in the upstream regulatory region of the MSTN gene are beneficial to the rabbit soma development, and the mutations can be used as molecular markers for the selection of the meat quality of rabbits.

  3. Studied and compared mRNA levels of myostatin (MSTN), myogenin (MyoG (zeige MYOG Antikörper)), and myosin heavy chain (MyHC (zeige MYH13 Antikörper)) in skeletal muscles of two rabbit breeds with different body sizes and growth rates.

  4. indicated that MSTN is not an important source of variability for performance traits, at least in the rabbit population

Myostatin (MSTN) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.

Genbezeichner und Symbole assoziert mit anti-Myostatin (MSTN) Antikörper

  • myostatin (MSTN) Antikörper
  • myostatin b (mstnb) Antikörper
  • myostatin (AaeL_AAEL003224) Antikörper
  • myostatin (BRAFLDRAFT_290840) Antikörper
  • myostatin (Mstn) Antikörper
  • myostatin (mstn) Antikörper
  • myostatin (LOC100125998) Antikörper
  • Cmpt Antikörper
  • GDF-8 Antikörper
  • Gdf8 Antikörper
  • MSLHP Antikörper
  • mstn Antikörper
  • NV13143 Antikörper
  • zgc:109749 Antikörper

Bezeichner auf Proteinebene für anti-Myostatin (MSTN) Antikörper

Growth/differentiation factor 8 , growth/differentiation factor-8 , GDF-8 , growth differentiation factor 8 , growth/differentiation factor 8 , mstn-1 , myostatin-1 , myostatin-B , zfMSTN-1 , myostatin , compact

GENE ID SPEZIES
100303659 Meleagris gallopavo
798441 Danio rerio
5577632 Aedes aegypti
7221321 Branchiostoma floridae
100118233 Nasonia vitripennis
100379652 Ictalurus punctatus
100529165 Oryzias latipes
2660 Homo sapiens
17700 Mus musculus
29152 Rattus norvegicus
373964 Gallus gallus
399534 Sus scrofa
281187 Bos taurus
403433 Canis lupus familiaris
100860887 Capra hircus
100033832 Equus caballus
443449 Ovis aries
100735599 Cavia porcellus
100125998 Oryctolagus cuniculus
710114 Macaca mulatta
100968757 Pan paniscus
470605 Pan troglodytes
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