anti-Myosin Light Chain Kinase (MYLK) Antikörper

MYLK, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. Zusätzlich bieten wir Ihnen Myosin Light Chain Kinase Kits (29) und Myosin Light Chain Kinase Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MYLK 4638 Q15746
MYLK 288057  
MYLK 107589  
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Top anti-Myosin Light Chain Kinase Antikörper auf antikoerper-online.de

Showing 10 out of 95 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of MYLK3 Antibody (N-term) (ABIN392494) in A375 cell line lysates (35 µg/lane). MYLK3(arrow) was detected using the purified polyclonal antibody. Western blot analysis of anti-MYLK3 Antibody (N-term) (ABIN392494) in mouse heart tissue lysates (35 µg/lane). MYLK3(arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Western blot analysis in K562 cell line lysates (35ug/lane) using MLCK Antibody . This demonstrates this antibody detected the MLCK protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Huhn Kaninchen Unkonjugiert WB Western blot analysis of MLCK1 expression in HeLa (A), SP2/0 (B), H9C2 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma Western blot analysis of anti-MLCK-long Pab (ABIN392495) in mouse brain tissue lysate. MLCK-long (Arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
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Huhn Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
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Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p) Formalin-fixed and paraffin embedded rat colon labeled with Anti-MLCK Polyclonal Antibody, Unconjugated (ABIN1386218) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
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MYLK Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Myosin Light Chain Kinase Antikörper

  1. Human Polyclonal MYLK Primary Antibody für IHC (p), WB - ABIN392494 : Rossi, Ralay Ranaivo, Patel, Chrzaszcz, Venkatesan, Wainwright: Albumin causes increased myosin light chain kinase expression in astrocytes via p38 mitogen-activated protein kinase. in Journal of neuroscience research 2011 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal MYLK Primary Antibody für IHC (p), WB - ABIN392495 : Rossi, Todd, Daniels, Bazan, Belayev: Interferon Stimulated Gene 15 upregulation precedes the development of blood brain barrier disruption and cerebral edema after traumatic brain injury in young mice. in Journal of neurotrauma 2015 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Myosin Light Chain Kinase Interaktionspartner

Human Myosin Light Chain Kinase (MYLK) Interaktionspartner

  1. loss of MLCK contributes to the migratory properties of epithelial cells resulting from changes in cell-cell and cell-matrix adhesions, and increased epidermal growth factor receptor (zeige EGFR Antikörper) signaling.

  2. Sixty-seven experienced runners competed in a marathon race. The MLCK genotype (C37885A) of these marathoners was determined. CA heterozygotes for MLCK C37885A might present higher exercise-induced muscle damage after a marathon competition than CC counterparts.

  3. these Acute respiratory distress syndrome (ARDS)-associated MYLK cytosine-guanine dinucleotides with effect modification by ethnicity and local modified cytosine quantitative trait loci suggest that MYLK epigenetic variation and local genetic background may contribute to health disparities observed in ARDS.

  4. mechanical stress and MYLK single nucleotide polymorphism regulate MYLK alternative splicing.

  5. Rebeccamycin attenuates TNF-alpha (zeige TNF Antikörper)-induced disruption of intestinal epithelial barrier integrity by inducing claudin-5 (zeige CLDN5 Antikörper) expression and suppressing MLCK production via Chk1 (zeige CHEK1 Antikörper) activation.

  6. Data show that alterations in myosin light chain kinase activity, claudin-15 (zeige CLDN15 Antikörper) and claudin-2 (zeige CLDN2 Antikörper) expression are associated with gluten-induced symptomatology and intestinal permeability changes in diarrhea-predominant irritable bowel syndrome (IBS-D).

  7. PXR (zeige NR1I2 Antikörper) regulates the intestinal epithelial barrier during inflammation by modulating cytokine-induced MLCK expression and JNK1 (zeige MAPK8 Antikörper)/2 activation

  8. A 2-bp deletion in myosin light chain kinase (c3272_3273del, p.Ser1091*) that led to a premature stop codon have a high risk of presenting with an acute aortic dissection or rupture.

  9. In contrast to mylk2 (zeige MYLK2 Antikörper) and mylk3 (zeige MYLK3 Antikörper), mylk1 has a complex structure, and multiple protein products of the mylk1 gene are expressed in most if not all cell types. This review deals with the mylk1 gene and its protein products- multiple MLCK isoforms and noncatalytic KRP/telokin protein. [Review]

  10. Likely pathogenic variants included a TGFB2 (zeige TGFB2 Antikörper) variant in one patient and a SMAD3 (zeige SMAD3 Antikörper) variant in another. These variants have been reported previously in individuals with similar phenotypes. Variants of uncertain significance of particular interest included novel variants in MYLK and MFAP5 (zeige MFAP5 Antikörper), which were identified in a third patient

Cow (Bovine) Myosin Light Chain Kinase (MYLK) Interaktionspartner

  1. Histamine induces myosin light chain (MLC)phosphorylation via MYLK, suggesting regulatory role for MLC in controlling corneal epithelial permeability.

Rabbit Myosin Light Chain Kinase (MYLK) Interaktionspartner

  1. evaluated the spatial arrangement of the catalytic/regulatory domain, three immunoglobulin-related motifs, one fibronectin-related motif, a repetitive, proline-rich segment, and, at the N-terminus, a unique F-actin-binding domain.

Mouse (Murine) Myosin Light Chain Kinase (MYLK) Interaktionspartner

  1. telokin may play a role in attenuating constitutive myosin light chain phosphorylation

  2. MLCK is linked to timely blastocyst formation, though it is dispensable for oocyte meiotic maturation

  3. NF-kappaB (zeige NFKB1 Antikörper) novel partner within endothelial cells

  4. MLCK regulates cell migration in a myosin regulatory light chain phosphorylation-independent mechanism.

  5. nmMlck modulates IL-1beta (zeige IL1B Antikörper)-mediated downregulation of Cldn5 (zeige CLDN5 Antikörper) in brain microvascular endothelial cells.

  6. a prominent effect of the multifunctional microRNA-155 in endothelial cells is modulation of phenotype through alterations in RhoA, myosin light chain kinase expression, and actin cytoskeleton organization

  7. CArG element in intron 15 of the mylk1 gene is necessary for maximal expression of the 130-kDa smMLCK and that the 130-kDa smMLCK isoform is specifically required to regulate smooth muscle contractility

  8. In immune-mediated inflammatory bowel disease, tight junction dysregulation and barrier loss is induced by MLCK, but at advanced stages, barrier loss is MLCK-independent.

  9. Claudin-2 (zeige CLDN2 Antikörper) assumes an important role in colorectal inflammation, and furthermore implicates the involvement of MLCK in colon inflammation.

  10. involved in IL-1beta (zeige IL1B Antikörper)-induced increase in intestinal permeability

Myosin Light Chain Kinase (MYLK) Antigen-Profil

Protein Überblick

This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.

Genbezeichner und Symbole assoziert mit MYLK

  • myosin light chain kinase (MYLK) Antikörper
  • myosin light chain kinase (Mylk) Antikörper
  • myosin, light polypeptide kinase (Mylk) Antikörper
  • 9530072E15Rik Antikörper
  • A930019C19Rik Antikörper
  • AAT7 Antikörper
  • AW489456 Antikörper
  • KRP Antikörper
  • Mlck Antikörper
  • MLCK1 Antikörper
  • MLCK108 Antikörper
  • MLCK210 Antikörper
  • MSTP083 Antikörper
  • MYLK1 Antikörper
  • SMMLCK Antikörper

Bezeichner auf Proteinebene für MYLK

kinase related protein, telokin , myosin, light chain kinase , myosin light chain kinase , myosin light chain kinase, smooth muscle-like , kinase-related protein , myosin light chain kinase, smooth muscle , myosin, light polypeptide kinase , smooth muscle myosin light chain kinase , telokin , MLCK , smooth muscle myosin light chain kinase (61-kDa active fragment)

GENE ID SPEZIES
460640 Pan troglodytes
488012 Canis lupus familiaris
715422 Macaca mulatta
100481263 Ailuropoda melanoleuca
4638 Homo sapiens
288057 Rattus norvegicus
338037 Bos taurus
396848 Sus scrofa
100009143 Oryctolagus cuniculus
443334 Ovis aries
396445 Gallus gallus
100714177 Cavia porcellus
107589 Mus musculus
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