anti-Myosin Light Chain 2 (MYL2) Antikörper

MYL2 encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK).

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human MYL2 MYL2 4633 P10916
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Weitere Antikörper gegen Myosin Light Chain 2 Interaktionspartner

Human Myosin Light Chain 2 (MYL2) Interaktionspartner

  1. that EZH2 (zeige EZH2 Antikörper) is phosphorylated by the DNA damage responsive complex DNA-PK and regulates DNA damage-mediated T-cell apoptosis.

  2. differential regulation of PKA and cell stiffness in unconfined versus confined cells is abrogated by dual, but not individual, inhibition of Piezo1 and myosin II.

  3. DNA-PKcs (zeige PRKDC Antikörper) is a potent regulator of IL-2 (zeige IL2 Antikörper) production in T lymphocytes.

  4. Mutation in myosin regulatory light chain gene is associated with defective myosin motor function that ultimately result in pathological hypertrophic remodeling.

  5. Lipolysis-stimulated lipoprotein receptors (LSRs) localized to bicellular junctions in association with myosin regulatory light chain 2 (MRLC2 (zeige MYL12B Antikörper)) at low cell densities and to tricellular contacts when myosin phosphatase target subunit 1 (MYPT1 (zeige PPP1R12A Antikörper)) localized to the bicellular regions.

  6. Structural dynamics-based approach reveals that the E56G mutation in human ventricular essential light chain affects the structure of the actin-myosin complex in the presence of ATP. The mutation increases the population in the S structural state (increasing the duty ratio), and changes the structure of the W state, so that it more closely resembles the S state.

  7. TMU-35435 enhances etoposide cytotoxicity by regulating ubiquitin-proteasomal degradation of DNA-PKcs (zeige PRKDC Antikörper) and inhibiting the DNA repair pathway in triple negative breast cancer cells.

  8. DNA-PK directly phosphorylates hSSB1 (zeige SSBP1 Antikörper) at serine residue 134. While this modification is largely suppressed in undamaged cells by PPP-family protein phosphatases, S134 phosphorylation is enhanced following the disruption of replication forks and promotes cellular survival.

  9. DNA-PK activity in peripheral blood lymphocytes might be a useful marker for predicting prostate-specific antigen (zeige KLK3 PLURAL_@3975@) relapse and urinary toxicity, possibly contributing to personalized treatment of prostate cancer.

  10. Data suggest that the model can replicate amplified p53 (zeige TP53 Antikörper) responses under DNA-PK inhibition and provide insights into cell fate decision by manipulating p53 (zeige TP53 Antikörper) dynamics.

Fruit Fly (Drosophila melanogaster) Myosin Light Chain 2 (MYL2) Interaktionspartner

  1. cycles of myosin-mediated contraction and relaxation, tightly linked to Cdc2 (zeige CDK1 Antikörper) and Rho kinase (zeige ROCK1 Antikörper) activity, are directly responsible for the axial expansion of the syncytial nuclei.

Xenopus laevis Myosin Light Chain 2 (MYL2) Interaktionspartner

  1. Ku80 (zeige XRCC5 Antikörper) is susceptible to proteolytic degradation when not dimerized with Ku70 (zeige XRCC6 Antikörper); dimer induces DNA-PK activity; evidence that interacting domain(s) of Xenopus DNA-PKcs (zeige PRKDC Antikörper) is conserved so as to interact with human Ku, reconstituting a functional holoenzyme

Myosin Light Chain 2 (MYL2) Antigen-Profil

Protein Überblick

This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.

Genbezeichner und Symbole assoziert mit MYL2

  • myosin, light chain 2, regulatory, cardiac, slow (MYL2) Antikörper
  • Myosin light chain 2 (Mlc2) Antikörper
  • protein kinase, DNA-activated, catalytic polypeptide (PRKDC) Antikörper
  • protein kinase, DNA-activated, catalytic polypeptide (prkdc) Antikörper
  • CG2184 Antikörper
  • CMH10 Antikörper
  • DmelCG2184 Antikörper
  • Dmlc2 Antikörper
  • DmMLC2 Antikörper
  • DNA-PKCS Antikörper
  • dnapk Antikörper
  • dnpk1 Antikörper
  • dro MLC-2 Antikörper
  • hyrc Antikörper
  • hyrc1 Antikörper
  • Ifm(3)99Eb Antikörper
  • l(3)99Eb Antikörper
  • LC2 Antikörper
  • MLC-2 Antikörper
  • MLC2 Antikörper
  • MRLC Antikörper
  • MYL2 Antikörper
  • p350 Antikörper
  • PRKDC Antikörper
  • prkdc-A Antikörper
  • RLC Antikörper
  • RLC2 Antikörper
  • xrcc7 Antikörper

Bezeichner auf Proteinebene für MYL2

MLC-2 , MLC-2v , RLC of myosin , cardiac ventricular myosin light chain 2 , myosin light chain 2 , myosin regulatory light chain 2, ventricular/cardiac muscle isoform , myosin, light polypeptide 2, regulatory, cardiac, slow , regulatory light chain of myosin , slow cardiac myosin regulatory light chain 2 , myosin light chain 2, isoform A , CG2184-PA , Mlc2-PA , myosin LC2 , muscle-specific myosin regulatory light chain , myosin light Chain-2 , myosin regulatory light chain , myosin light chain 2, isoform B , CG2184-PB , Mlc2-PB , DNA-PK catalytic subunit , DNA-dependent protein kinase catalytic subunit , hyper-radiosensitivity of murine scid mutation, complementing 1 , p460 , protein kinase, DNA-activated, catalytic polypeptide , protein kinase catalytic subunit (DNA-dependent protein kinase) , DNA-PKcs , DNA-activated protein kinase catalytic polypeptide , DNA-dependent protein kinase catalytic subunit-like

4633 Homo sapiens
43587 Drosophila melanogaster
5591 Homo sapiens
282003 Bos taurus
373602 Xenopus laevis
395376 Gallus gallus
418814 Gallus gallus
464165 Pan troglodytes
474176 Canis lupus familiaris
512740 Bos taurus
100125348 Oryctolagus cuniculus
100224961 Taeniopygia guttata
100399020 Callithrix jacchus
100586225 Nomascus leucogenys
100633457 Amphimedon queenslandica
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