anti-Myocilin (MYOC) Antikörper

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. Zusätzlich bieten wir Ihnen Myocilin Proteine (23) und Myocilin Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MYOC 17926 O70624
MYOC 4653 Q99972
MYOC 81523 Q9R1J4
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Top anti-Myocilin Antikörper auf antikoerper-online.de

Showing 10 out of 62 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, IHC (p) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
517,00 €
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Meerschweinchen Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Maus Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 11 bis 13 Tage
282,86 €
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Human Maus Unkonjugiert EIA, IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
583,00 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC (p) Immunohistochemistry-Paraffin: Myocilin Antibody [NBP1-40064] - Analysis of anti-MYOC antibody with human eye, retina at concentration 5 ug/ml. 0.05 mg Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
Details
Human Maus Unkonjugiert WB Western Blot analysis of MYOC expression in transfected 293T cell line by MYOC monoclonal antibody (M02), clone 2B4. Lane 1: MYOC transfected lysate(57 KDa). Lane 2: Non-transfected lysate. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Maus Unkonjugiert WB Western blot analysis of MYOC over-expressed 293 cell line, cotransfected with MYOC Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of MYOC expression in transfected 293T cell line by MYOC monoclonal antibody (M01), clone 4F8. Lane 1: MYOC transfected lysate(57 KDa). Lane 2: Non-transfected lysate. 50 μg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Gibbon Kaninchen Unkonjugiert IHC, ELISA 0.05 mg Anmelden zum Anzeigen 6 bis 8 Tage
538,22 €
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Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
462,00 €
Details
Human Maus Unkonjugiert IHC (p), RNAi, ELISA, WB Human Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
565,71 €
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MYOC Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)


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Rat (Rattus)


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Am meisten referenzierte anti-Myocilin Antikörper

  1. Mouse (Murine) Polyclonal MYOC Primary Antibody für IHC, WB - ABIN3022197 : Polansky, Fauss, Chen, Chen, Lütjen-Drecoll, Johnson, Kurtz, Ma, Bloom, Nguyen: Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene product. in Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde 1997 (PubMed)
    Zeige alle 5 Referenzen für 3022197

Weitere Antikörper gegen Myocilin Interaktionspartner

Mouse (Murine) Myocilin (MYOC) Interaktionspartner

  1. mutant myocilin induces abnormal ECM (zeige MMRN1 Antikörper) accumulation in the ER of TM cells, which may be responsible for reduced outflow facility and IOP elevation in myocilin-associated glaucoma.

  2. Mutated myocilin and heterozygous Sod2 (zeige SOD2 Antikörper) deficiency act synergistically in a mouse model of open-angle glaucoma

  3. myocilin promotes cell proliferation and resistance to apoptosis via the ERK1/2 (zeige MAPK1/3 Antikörper) MAPK (zeige MAPK1 Antikörper) signaling pathway.

  4. Myocilin binds to ErbB2 (zeige ERBB2 Antikörper)/ErbB3 (zeige ERBB3 Antikörper), activates these receptors, and affects the downstream PI3K-AKT (zeige AKT1 Antikörper) signaling pathway

  5. Myocilin also stimulated osteogenic differentiation of wild-type MSCs, which was associated with activation of the p38 (zeige CRK Antikörper), Erk1/2 (zeige MAPK1/3 Antikörper), and JNK (zeige MAPK8 Antikörper) MAP kinase (zeige MAPK1 Antikörper) signaling pathways

  6. We suggest that intracellular myocilin plays a role as a regulator of muscle hypertrophy pathways, acting through the components of dystrophin (zeige DMD Antikörper) associated protein complex.

  7. The TIGR is implicated in resistance to oxidative stress. Despite the presence of a SOD motif, which is necessary for protection in mammalian cells, the protein is not a functional SOD, but might be involved in SOD activity.

  8. TIGR is a newly identified component of the CNS glial scar that is likely to contribute to neuronal regenerative failure characteristic of the mammalian CNS.

  9. Results do not support a causative role for increased MYOC levels or the MYOC gene in steroid-induced glaucoma.

  10. Results show that myocilin and gamma-synuclein (zeige SNCG PLURAL_@30211@) interact and as a result, myocilin's properties are changed.

Human Myocilin (MYOC) Interaktionspartner

  1. The four detected MYOC mutations appeared to be associated with morphologic changes in the trabecular meshwork and the underlying pathogenesis of a subtype of familial primary open angle glaucoma.

  2. The mutations c.1456C < T (p.L486F) in MYOC and c.322G < A (p.V108I) in B4GALT3 (zeige B4GALT3 Antikörper) are likely responsible for the pathogenesis of Primary Open-angle Glaucoma in this family.

  3. Our findings demonstrated that MYOC cascade genetic testing for POAG allows identification of at-risk individuals at an early stage or even before signs of glaucoma are present. To our knowledge, this is the first study to demonstrate the clinical utility of predictive genetic testing for MYOC glaucoma.

  4. regulation by retinoic acid acts through the MYOC promoter which contains a critical cluster of four retinoic acid responsive (zeige GPRC5A Antikörper) elements (RAREs), with the RARE-DR2 presenting the strongest effect and binding the RARalpha (zeige RARA Antikörper)/RXRalpha (zeige RXRA Antikörper) heterodimer.

  5. Five out of 30 families with PCG (16.7%) had disease attributable to CYP1B1 (zeige CYP1B1 Antikörper) alterations suggesting that CYP1B1 (zeige CYP1B1 Antikörper) is not the major gene causing PCG in Vietnamese unlike in the case of Arab or Romany patients.

  6. The present study provides insight into the genetic or haplotype variants of MYOC and OPTN (zeige OPTN Antikörper) genes contributing to primary glaucoma. Haplotype variants identified in the present study may be regarded as potential contributing factors of primary glaucoma in Korea.

  7. Familial linkage studies for primary angle-closure glaucoma have been performed and identified MYOC causative primary angle-closure glaucoma disease

  8. The rate of CYP1B1 (zeige CYP1B1 Antikörper) mutations in Lebanese patients with primary congenital glaucoma (PCG) is lower than that reported in other Arab and Middle Eastern populations and suggests other genes are responsible.

  9. Data show that predictive genetic testing for early onset Myocilin glaucoma can facilitate early detection of disease or discharge from routine ophthalmic examinations.

  10. This study does not confirm a role for genetic variants in the MYOC, NR3C1 (zeige NR3C1 Antikörper) and FKBP5 (zeige FKBP5 Antikörper) genes in the pathogenesis of corticosteroid-induced ocular hypertension.

Cow (Bovine) Myocilin (MYOC) Interaktionspartner

  1. endoproteolytic processing might regulate the activity of myocilin; the inhibition of the processing by pathogenic mutations impairs the normal role of myocilin

Myocilin (MYOC) Antigen-Profil

Protein Überblick

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Genbezeichner und Symbole assoziert mit anti-Myocilin (MYOC) Antikörper

  • myocilin (MYOC) Antikörper
  • myocilin (myoc) Antikörper
  • myocilin (Myoc) Antikörper
  • myocilin, trabecular meshwork inducible glucocorticoid response (MYOC) Antikörper
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  • GLC1A Antikörper
  • GPOA Antikörper
  • JOAG Antikörper
  • JOAG1 Antikörper
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  • zgc:136645 Antikörper

Bezeichner auf Proteinebene für anti-Myocilin (MYOC) Antikörper

myocilin , trabecular meshwork-induced glucocorticoid response protein , mutated trabecular meshwork-induced glucocorticoid response protein

GENE ID SPEZIES
397046 Sus scrofa
548602 Danio rerio
704406 Macaca mulatta
17926 Mus musculus
4653 Homo sapiens
81523 Rattus norvegicus
281342 Bos taurus
101087632 Felis catus
490344 Canis lupus familiaris
100008897 Oryctolagus cuniculus
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