Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) ELISA Kits

Histone methyltransferase that plays an essential role in early development and hematopoiesis. Zusätzlich bieten wir Ihnen Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 Antikörper (10) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
MLL1 315606  
MLL1 214162 P55200
MLL1    
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Top Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Hund 0.1 ng/mL 0.5   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Ratte 0.1 ng/mL 0.5   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Maus 0.1 ng/mL 0.5   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Kaninchen 0.1 ng/mL 0.5   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Meerschweinchen 0.1 ng/mL 0.5   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Affe 0.1 ng/mL 0.5   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Schwein
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Huhn
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Weitere ELISA Kits für Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 Interaktionspartner

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) Interaktionspartner

  1. Collectively, these data indicated that ATR (zeige ATR ELISA Kits) or ATM (zeige ATM ELISA Kits) inhibition represent potential therapeutic strategies for the treatment of AML (zeige RUNX1 ELISA Kits), especially MLL (zeige MLL ELISA Kits)-driven leukemias.

  2. Epigenomic profiling indicates an abnormal H3K79me2 pattern on MLL (zeige MLL ELISA Kits)-fusion targeted genes, but the molecular mechanism underlying this epigenetic dependency is not well understood.

  3. NUP98 (zeige NUP98 ELISA Kits)-HOXA9 (zeige HOXA9 ELISA Kits) interacts with MLL (zeige MLL ELISA Kits) via the NUP98 (zeige NUP98 ELISA Kits) second FG repeat domain. In the absence of MLL (zeige MLL ELISA Kits) (in knockout mice), NUP98 (zeige NUP98 ELISA Kits)-HOXA9 (zeige HOXA9 ELISA Kits)-induced cell immortalization and leukemogenesis are severely inhibited. MLL (zeige MLL ELISA Kits) is important for the recruitment of NUP98 (zeige NUP98 ELISA Kits)-HOXA9 (zeige HOXA9 ELISA Kits) to the HOXA locus and for NUP98 (zeige NUP98 ELISA Kits)-HOXA9 (zeige HOXA9 ELISA Kits)-induced HOXA gene expression. MLL (zeige MLL ELISA Kits) is crucial for NUP98 (zeige NUP98 ELISA Kits)-HOXA9 (zeige HOXA9 ELISA Kits) leukemia initiation.

  4. Atg5 (zeige ATG5 ELISA Kits)-dependent autophagy contributes to the development of acute myeloid leukemia (zeige BCL11A ELISA Kits) in an MLL (zeige MLL ELISA Kits)-AF9 (zeige MLLT3 ELISA Kits)-driven mouse model.

  5. These results reveal a cooperative transcriptional activation mechanism of AEP (zeige LGMN ELISA Kits) and DOT1L (zeige DOT1L ELISA Kits) and suggest a molecular rationale for the simultaneous inhibition of the MLL (zeige MLL ELISA Kits) fusion-AF4 complex and DOT1L (zeige DOT1L ELISA Kits) for more effective treatment of MLL (zeige MLL ELISA Kits)-rearranged leukemia.

  6. This study demonstrated that Kmt2a (zeige MLL ELISA Kits) regulates synaptic plasticity in striatal neurons and provides an epigenetic drug target for anxiety and dopamine-mediated behaviors.

  7. Inactivation of Kmt2a in Men1-deficient mice accelerated pancreatic islet tumorigenesis and shortened the average life span. Increases in cell proliferation were observed in mouse pancreatic islet tumors upon inactivation of both Kmt2a and Men1.

  8. Data suggest that RAS-homolog enriched in brain protein (Rheb1) promotes MLL-AF9 fusion protein initiated acute myeloid leukemia (AML) progression through target of rapamycin complex 1 (mTORC1) signaling pathway.

  9. HoxBlinc RNA Recruits Set1 (zeige SETD1A ELISA Kits)/MLL (zeige MLL ELISA Kits) Complexes to Activate Hox (zeige MSH2 ELISA Kits) Gene Expression Patterns and Mesoderm Lineage Development.

  10. MLL1 and DOT1L (zeige DOT1L ELISA Kits) cooperate with meningioma-1 to induce acute myeloid leukemia (zeige BCL11A ELISA Kits).

Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) Antigen-Profil

Beschreibung des Gens

Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the MLL1/MLL complex, it specifically mediates H3K4me, a specific tag for epigenetic transcriptional activation. Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity. Has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', while it has higher activity toward H3 acetylated on 'Lys-9'. Required for transcriptional activation of HOXA9. Promotes PPP1R15A-induced apoptosis (By similarity).

Genbezeichner und Symbole assoziert mit MLL1

  • lysine methyltransferase 2A (Kmt2a) Antikörper
  • lysine (K)-specific methyltransferase 2A (Kmt2a) Antikörper
  • 6430520K01 Antikörper
  • ALL-1 Antikörper
  • All1 Antikörper
  • Cxxc7 Antikörper
  • HRX Antikörper
  • HTRX1 Antikörper
  • mKIAA4050 Antikörper
  • Mll Antikörper
  • Mll1 Antikörper

Bezeichner auf Proteinebene für MLL1

Mixed-lineage leukemia (also acute lymphocytic leukemia 1 or tritorax Drosophila gene) , histone-lysine N-methyltransferase MLL , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) , myeloid/lymphoid or mixed-lineage leukemia 1 , histone-lysine N-methyltransferase 2A , lysine N-methyltransferase 2A , myeloid/lymphoid or mixed-lineage leukemia protein 1 , trithorax Drosophila , zinc finger protein HRX

GENE ID SPEZIES
315606 Rattus norvegicus
214162 Mus musculus
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