Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 11 (MLLT11) ELISA Kits

The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. Zusätzlich bieten wir Ihnen MLLT11 Antikörper (22) und MLLT11 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human MLLT11 MLLT11 10962 Q13015
Anti-Maus MLLT11 MLLT11 56772 P97783
Anti-Ratte MLLT11 MLLT11 295264 Q5M971
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Weitere ELISA Kits für MLLT11 Interaktionspartner

Human Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 11 (MLLT11) Interaktionspartner

  1. These results suggest that AF1q would have a role as an enhancer in generation of stem-like population through activation of Wnt (zeige WNT2 ELISA Kits) signaling pathway.

  2. Findings indicate that breast cancer cells with a hyperactive AF1q/TCF7 (zeige TCF7 ELISA Kits)/CD44 (zeige CD44 ELISA Kits) regulatory axis in the primary sites may represent "metastatic founder cells" which have invasive properties.

  3. Results demonstrate that AF1q gene transcription is regulated by REST through direct binding at -383 to -363 bp of AF1q promoter.

  4. AF1Q had a KFERQ-like motif.

  5. AF1q plays a role in the onset of basal apoptosis in ovarian cancer cells, thus providing new information about the activity of this protein whose biologic functions are mostly unknown

  6. Using in vitro assays based on either forced expression or shRNA-mediated silencing of AF1q, the study provides evidence that the protein promotes T- over B-cell differentiation in multipotent hematopoietic progenitors.

  7. AF1q up-regulation of BAD is through its effect on NF-kappaB (zeige NFKB1 ELISA Kits) and this may hint of its oncogenic mechanism in cancer.

  8. The ectopic expression of human AF1q triggered the expression of the neuronal marker TuJ1 in non-neuronal human embryonic kidney (HEK) cells.

  9. overexpression of AF1Q leads to more progression in human breast cancer

  10. The study provides the first evidence that AF1q plays a critical role in the regulation of apoptosis and drug resistance.

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 11 (MLLT11) Interaktionspartner

  1. MLLT11 is a pan-neuronal marker, suggesting a role in neural differentiation in the central nervous system and neural crest-cell derived peripheral ganglia

  2. The mouse Af1q, homologue of human AF1q, was found to be significantly up-regulated during the neuronal production from neural stem cells

MLLT11 Antigen-Profil

Beschreibung des Gens

The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1\;11)(q21\;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested.

Genbezeichner und Symbole assoziert mit MLLT11

  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 (MLLT11) Antikörper
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 (Mllt11) Antikörper
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 (mllt11) Antikörper
  • Af1q Antikörper
  • AI839562 Antikörper
  • fc23g02 Antikörper
  • RGD1305525 Antikörper
  • RP11-316M1.10 Antikörper
  • si:ch211-210h11.4 Antikörper
  • wu:fc23g02 Antikörper
  • Zfp692 Antikörper

Bezeichner auf Proteinebene für MLLT11

protein AF1q , ALL1 fused gene from chromosome 1q , ALL1-fused gene from chromosome 1q , zinc finger protein 692 , AF1Q protein

GENE ID SPEZIES
100520242 Sus scrofa
100682887 Canis lupus familiaris
10962 Homo sapiens
56772 Mus musculus
295264 Rattus norvegicus
539519 Bos taurus
100173899 Pongo abelii
563531 Danio rerio
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