anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 1 (MLLT1) Antikörper

Capable of activating transcription from synthetic reporter genes in both lymphoid and myeloid cells.. Zusätzlich bieten wir Ihnen MLLT1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MLLT1 301119  
MLLT1 4298 Q03111
MLLT1 64144  
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Top anti-MLLT1 Antikörper auf antikoerper-online.de

Showing 10 out of 41 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-MLLT1 Antibody Titration: </b>1.4ug/ml<br><b>Positive Control: </b>Raji cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of anti-MLLT1 Pab (ABIN390126) in A257 cell line lysate (35 µg/lane). MLLT1(arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: MLLT1 Antibody [NBP1-84840] - Staining of human hippocampus shows strong cytoplasmic and nucleolar positivity in neuronal cells. Immunocytochemistry/Immunofluorescence: MLLT1 Antibody [NBP1-84840] Staining of human cell line U-251MG shows positivity in nucleoli & nucleus but not nucleoli. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with MLLT1 antibody ABIN214673 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Kaninchen Unkonjugiert IP 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: MLLT1 Antibody [NBP1-26653] - Section of human testicular seminoma. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert IHC, ELISA 0.05 mg Anmelden zum Anzeigen 2 bis 3 Tage
$550.00
Details

MLLT1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Rat (Rattus)


Human , , ,
,
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, , , , ,
Mouse (Murine)


Am meisten referenzierte anti-MLLT1 Antikörper

  1. Human Polyclonal MLLT1 Primary Antibody für WB - ABIN390126 : Bitoun, Oliver, Davies: The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling. in Human molecular genetics 2007 (PubMed)

  2. Human Polyclonal MLLT1 Primary Antibody für ICC, IF - ABIN4334892 : Perlman, Gadd, Arold, Radhakrishnan, Gerhard, Jennings, Huff, Guidry Auvil, Davidsen, Dome, Meerzaman, Hsu, Nguyen, Anderson, Ma, Mungall, Moore, Marra, Mullighan, Ma, Wheeler, Hampton et al.: MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours. ... in Nature communications 2015 (PubMed)

Weitere Antikörper gegen MLLT1 Interaktionspartner

Human Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 1 (MLLT1) Interaktionspartner

  1. data identify ENL as a histone acetylation reader that regulates oncogenic transcriptional programs in acute myeloid leukaemia, and suggest that displacement of ENL from chromatin may be a promising epigenetic therapy, alone or in combination with BET inhibitors, for aggressive leukaemia

  2. MLL (zeige MLL Antikörper)-ENL dysregulated the proliferative and repopulating capacity of hematopoietic stem cells.

  3. Recurrent mutations within Wilms tumours involve the highly conserved YEATS domain of MLLT1.

  4. Novel splice isoform of Mllt1 is documented and confirmed that both Mllt1 mRNA isoforms are translated. The data support that MLLT1 protein isoforms display distinct stage-specific expression during spermiogenesis and adult tissues.

  5. Data suggest that AT mutated protein ATM (zeige ATM Antikörper)-dependent phosphorylation of ENL (MLLT1) protein functions as switch from elongation to Polycomb (zeige CBX2 Antikörper)-mediated repression to preserve genome integrity.

  6. AF9 and its homolog ENL directly interact with AF4.

  7. MLL (zeige MLL Antikörper)-ENL Interaction with CBX8 (zeige CBX8 Antikörper) Is Required for Efficient Transformation.

  8. Data from a follow-up study in Rome suggest a particularly favorable prognosis for patients with acute lymphoblastic leukemia expressing the MLL (zeige MLL Antikörper)/ENL fusion gene.

  9. Three-way translocation involving MLL (zeige MLL Antikörper), MLLT1, and a novel third partner, NRXN1 (zeige NRXN1 Antikörper), in a patient with acute lymphoblastic leukemia and t(2;19;11) (p12 (zeige POLE4 Antikörper);p13.3;q23).

  10. ENL chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 1 (MLLT1) Interaktionspartner

  1. data identify ENL as a histone acetylation reader that regulates oncogenic transcriptional programs in acute myeloid leukaemia, and suggest that displacement of ENL from chromatin may be a promising epigenetic therapy, alone or in combination with BET inhibitors, for aggressive leukaemia

  2. define a specific pairing of two amino acids that creates a salt bridge between MLLT1/3 and AFF proteins that is critically important for MLL (zeige MLL Antikörper)-mediated transformation of HPCs

  3. demonstrate BAM11 transcriptional co-activation activity and its functional interaction with Btk (zeige BTK Antikörper)

  4. An intimate association between MLL (zeige MLL Antikörper) and RNA pol II (zeige POLR2F Antikörper) occurs at MLL (zeige MLL Antikörper) target genes in vivo that is required for normal initiation and/or transcriptional elongation.

  5. Overlapping expression of Af9 (zeige MLLT3 Antikörper) with Af4/Aff1 and Fmr2/Aff2 (zeige AFF2 Antikörper), two genes that are also related to neurodevelopmental diseases, as well as with the highly homologous Enl.

  6. Even genetically complex leukemias can be reversed on inactivation of the initiating MLL (zeige MLL Antikörper) fusion.

MLLT1 Antigen-Profil

Protein Überblick

Capable of activating transcription from synthetic reporter genes in both lymphoid and myeloid cells.

Genbezeichner und Symbole assoziert mit MLLT1

  • MLLT1, super elongation complex subunit (Mllt1) Antikörper
  • MLLT1, super elongation complex subunit (MLLT1) Antikörper
  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 L homeolog (mllt1.L) Antikörper
  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 (mllt1) Antikörper
  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 (Mllt1) Antikörper
  • AA407901 Antikörper
  • BAM11 Antikörper
  • ENL Antikörper
  • LTG19 Antikörper
  • MGC84026 Antikörper
  • MLLT1 Antikörper
  • YEATS1 Antikörper

Bezeichner auf Proteinebene für MLLT1

myeloid/lymphoid or mixed lineage leukemia translocation to 1 homolog , myeloid/lymphoid or mixed lineage-leukemia translocation to 1 homolog , protein ENL , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1 , ENL/MLL fusion , MLLT1/MLL fusion , YEATS domain-containing protein 1 , leukemia-associated protein MLLT1 , myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog , trithorax

GENE ID SPEZIES
301119 Rattus norvegicus
420089 Gallus gallus
447347 Xenopus laevis
485023 Canis lupus familiaris
504458 Bos taurus
702105 Macaca mulatta
740990 Pan troglodytes
100019539 Monodelphis domestica
100065400 Equus caballus
100158574 Xenopus (Silurana) tropicalis
4298 Homo sapiens
64144 Mus musculus
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