Myelin Protein Zero-Like 2 (MPZL2) ELISA Kits

Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Zusätzlich bieten wir Ihnen MPZL2 Antikörper (64) und MPZL2 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human MPZL2 MPZL2 10205 O60487
Anti-Maus MPZL2 MPZL2 14012  
Anti-Ratte MPZL2 MPZL2 300679  
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Weitere ELISA Kits für MPZL2 Interaktionspartner

Human Myelin Protein Zero-Like 2 (MPZL2) Interaktionspartner

  1. CLCA2 (zeige CLCA2 ELISA Kits) links junctional adhesion molecule (zeige AMICA1 ELISA Kits) EVA1, to cytosolic signaling proteins that modulate proliferation and differentiation.

  2. Findings highlight Eva1 as a novel regulator of GIC function and also provide new mechanistic insight into the role of noncanonical NF-kappaB (zeige NFKB1 ELISA Kits) activation in GIC.

  3. EVA (zeige SLC26A4 ELISA Kits) is expressed in human choroid plexus epithelial cells and CD4 (zeige CD4 ELISA Kits) T lymphocytes and regulates CD4 (zeige CD4 ELISA Kits)+ T lymphocyte adhesion to human choroid plexus epithelial cells in vitro. These data suggest a novel mechanism to regulate CNS immune surveillance.

Mouse (Murine) Myelin Protein Zero-Like 2 (MPZL2) Interaktionspartner

  1. EVA deficiency results in increased experimental autoimmune encephalomyelitis disease severity. EVA-knockout Mice have normal immune system development and choroid plexus morphology.

  2. modulation of Eva1 expression in thymocytes is crucial for lymphocyte physiological developmental progression and stromal differentiation

  3. These results suggest that EVA expressed in choroid plexus cells may regulate the permeability of the blood-CSF (zeige CSF2 ELISA Kits) barrier.

MPZL2 Antigen-Profil

Beschreibung des Gens

Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain\; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit MPZL2

  • myelin protein zero-like 2b (mpzl2b) Antikörper
  • myelin protein zero like 2 (MPZL2) Antikörper
  • myelin protein zero-like 2 (Mpzl2) Antikörper
  • cb837 Antikörper
  • Eva Antikörper
  • Eva1 Antikörper
  • mpzl2 Antikörper
  • wu:fb07b02 Antikörper

Bezeichner auf Proteinebene für MPZL2

epithelial V-like antigen 1 , myelin protein zero-like 2 , myelin protein zero-like protein 2

336830 Danio rerio
419779 Gallus gallus
699330 Macaca mulatta
10205 Homo sapiens
14012 Mus musculus
300679 Rattus norvegicus
540423 Bos taurus
489384 Canis lupus familiaris
100172793 Pongo abelii
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