anti-Myelin Basic Protein (MBP) Antikörper

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. Zusätzlich bieten wir Ihnen Myelin Basic Protein Kits (54) und Myelin Basic Protein Proteine (28) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MBP 4155 P02686
MBP 24547 P02688
MBP 17196 P04370
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Top anti-Myelin Basic Protein Antikörper auf antikoerper-online.de

Showing 10 out of 186 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert IHC (fro), IHC (p), WB Staining of white matter in human brain with Mouse anti MBP 2 mL Anmelden zum Anzeigen 7 bis 9 Tage
528,00 €
Details
Human Kaninchen Unkonjugiert EIA 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Rind (Kuh) Maus Unkonjugiert EIA, IHC (p), RIA   0.2 mg Anmelden zum Anzeigen 7 bis 9 Tage
495,00 €
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Human Maus Unkonjugiert EIA, IHC (fro), WB   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
484,00 €
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Rind (Kuh) Maus Unkonjugiert EIA, IHC (fro)   2 mL Anmelden zum Anzeigen 7 bis 9 Tage
484,00 €
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Rind (Kuh) Maus Unkonjugiert EIA, IHC (fro)   2 mL Anmelden zum Anzeigen 7 bis 9 Tage
528,00 €
Details
Ratte Kaninchen Unkonjugiert ELISA, WB Western blot analysis of tissue lysates using 1 µg/mL Rabbit Anti-Myelin Basic Protein Polyclonal Antibody (ABIN398883) The signal was developed with IRDyeTM 800 Conjugated Goat Anti-Rabbit IgG.Predicted Size: 14-33 KD Observed Size: 14-33 KD 40 μg Anmelden zum Anzeigen 6 bis 8 Tage
187,10 €
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Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 6 bis 8 Tage
318,48 €
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Human Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
300,95 €
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Rind (Kuh) Maus Unkonjugiert IHC (p), RIA, ELISA Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with MBP antibody ABIN462005 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with MBP antibody ABIN462005 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
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MBP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Mouse (Murine)
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Am meisten referenzierte anti-Myelin Basic Protein Antikörper

  1. Human Polyclonal MBP Primary Antibody für ICC, IHC - ABIN1078364 : Bleyer, Curths, Dahlmann, Wichmann, Bauer, Moritz, Braun, Knauf, Kaup, Gruber-Dujardin: Morphology and staining behavior of neutrophilic and eosinophilic granulocytes of the common marmoset (Callithrix jacchus). in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2016 (PubMed)

  2. Rat (Rattus) Polyclonal MBP Primary Antibody für ELISA, WB - ABIN1574105 : Kraitsy, Uecal, Grossauer, Bruckmann, Pfleger, Ropele, Fazekas, Gruenbacher, Patz, Absenger, Porubsky, Smolle-Juettner, Tezer, Molcanyi, Fasching, Schaefer: Repetitive long-term hyperbaric oxygen treatment (HBOT) administered after experimental traumatic brain injury in rats induces significant remyelination and a recovery of sensorimotor function. in PLoS ONE 2014 (PubMed)

Weitere Antikörper gegen Myelin Basic Protein Interaktionspartner

Human Myelin Basic Protein (MBP) Interaktionspartner

  1. t-PA (zeige PLAT Antikörper) binds to Lys91 in the MBP (zeige MBL2 Antikörper) NH2-terminal region and PLG (zeige PLG Antikörper) binds to Lys122 in the MBP (zeige MBL2 Antikörper) COOH-terminal region. This proximity promotes the activation of PLG (zeige PLG Antikörper) by t-PA (zeige PLAT Antikörper).

  2. Specific sites of post-translational modifications in multiple sclerosis patients are localized in two zones of MBP (zeige MBL2 Antikörper) suggests that these regions may be involved in antigen recognition by the body's immune surveillance machinery

  3. Results provide novel insights into the role of genetic variation within the MBP (zeige MBL2 Antikörper) gene predicting multiple sclerosis clinical course, both directly and by interaction with known environmental MS risk factors

  4. Deimination of myelin basic protein (MBP) by peptidylarginine deiminase (PAD) prevents its binding to the proteasome and decelerates its degradation by the proteasome in mammalian cells. Potential anticancer drug tetrazole analogue of chloramidine 2, at concentrations greater than 1 microM inhibits the enzymatic activity of PAD in vitro.

  5. This study observed a significantly increased myelin basic protein (MBP) and nuclear distribution protein nudE-like 1 (NDEL1 (zeige NDEL1 Antikörper)) mRNA levels in FEP patients compared with controls.

  6. myelin basic protein has a role in activating CD4 (zeige CD4 Antikörper)+ and CD8 (zeige CD8A Antikörper)+ T lymphocytes in multiple sclerosis

  7. B cells from relapsing-remitting multiple sclerosis patients produce TNFa (zeige TNF Antikörper) and IL6 (zeige IL6 Antikörper), and present MBP85-99 peptide

  8. IL-17 (zeige IL17A Antikörper)- and IL-22 (zeige IL22 Antikörper)-secreting myelin specific CD4 (zeige CD4 Antikörper)(+) T cells resistant to corticoids are associated with radiological activity of multiple sclerosis in early stages of the disease, mainly among Afrodescendant patients who, normally, have worse prognosis.

  9. Studies indicate that all myelin basic protein (MBP) isoforms are intrinsically disordered proteins (IDPs) that interact via molecular recognition fragments (MoRFs), which thereby undergo local disorder-to-order transitions.

  10. Reduced myelin basic protein-induced CD4 (zeige CD4 Antikörper)+ T-cell autoreactivity in interferon-beta (zeige IFNB1 Antikörper)-treated multiple sclerosis patients may be mediated by monocyte-derived interleukin-10 (zeige IL10 Antikörper)

Pig (Porcine) Myelin Basic Protein (MBP) Interaktionspartner

  1. Concentrations of MBP did not increase after injury in all age groups

  2. results provide a detailed picture of the MBP-CaM (zeige CALM Antikörper) interaction, including a 3D model of the complex between full-length proteins

  3. MBP-hydrolyzing antibodies may play an important role in multiple sclerosis pathogenesis

Cow (Bovine) Myelin Basic Protein (MBP) Interaktionspartner

  1. Deimination of myelin basic protein (MBP) by peptidylarginine deiminase (PAD) prevents its binding to the proteasome and decelerates its degradation by the proteasome in mammalian cells. Potential anticancer drug tetrazole analogue of chloramidine 2, at concentrations greater than 1 microM inhibits the enzymatic activity of PAD in vitro.

  2. Data suggest that hybrid protein composed of two different Myelin basic protein (MBP) isoforms (TandeMBP) might become a tool for in vitro assays to analyse various protein kinase (zeige CDK7 Antikörper) activities.

  3. trehalose completely avoid autocatalytic cleavage properties of MBP up to 4 days of incubation at 37 degrees C and pH 7.4.

  4. formation of an imine between inflammatory-derived aldehydes can lead to structural changes in MBP and a decrease in myelin stability

  5. results provide a detailed picture of the MBP-CaM (zeige KRIT1 Antikörper) interaction, including a 3D model of the complex between full-length proteins

  6. MBP can induce a dihydrocholesterol-dependent segregation of phases that can be further regulated by the electrolyte concentration in the subphase and the composition (type and proportion) of non-sterol lipids.

  7. Bovine MBP priming reduces expression of Foxp3 (zeige FOXP3 Antikörper) via nitric oxide in inducible nitric oxide synthase (zeige NOS2 Antikörper)-deficient mouse T cells.

  8. investigation of bovine myelin basic protein binding to triphosphoinositide

  9. There is a developmental regulation of posttranslationally modified forms of myelin basic protein into specific membrane microdomains.

  10. These results suggest that phospholipids and sulfatide and heparin may function as effective stimulators for autophosphorylation of GSK-3beta (zeige GSK3b Antikörper) and for the GSK-3beta (zeige GSK3b Antikörper)-mediated high phosphorylation of SH-binding proteins, including MBP and tau protein.

Mouse (Murine) Myelin Basic Protein (MBP) Interaktionspartner

  1. to further characterize the mechanism regulating mbp transcription, study defined M3 structure/function relationships; multiple M3 regulatory element combinations were found to drive expression in oligodendrocytes and Schwann cells with a minimal 129 bp sequence conferring expression in oligodendrocytes throughout myelin elaboration, maintenance and repair

  2. Results show the expression of sncRNA715 in Schwann cells and its inverse correlation with Mbp mRNA in cultured cells and the sciatic nerve. Its inhibitory effect on MBP was confirmed in differentiating primary Schwann cells.

  3. Results suggest that GAL (zeige GAL Antikörper) is a regulator of myelination, as demonstrated by MBP synthesis, and may be one of the myelination promoters

  4. Data indicate that 18.5 kDa myelin basic protein (MBP) segment upstream of the primary SH3-ligand is involved in interaction.

  5. Data suggest that prenatal alterations in expression of various fetal brain proteins (including up-regulation of Mbp) are associated with aberrant behavioral characteristics of transgenic mice that model autism-like behavior.

  6. Data suggest that hybrid protein composed of two different Myelin basic protein (MBP) isoforms (TandeMBP) might become a tool for in vitro assays to analyse various protein kinase (zeige CDK7 Antikörper) activities.

  7. Data indicate a role for myelin basic protein (MBP) isoforms in protein-protein interactions during membrane and cytoskeletal extension and remodeling in oligodendrocytes (OLGs).

  8. Disappearance of 21.5 pMBP (zeige PGRMC2 Antikörper) corresponded to demyelination and its reappearance corresponded to prevention of demyelination.

  9. Golli-BG21 enhanced SCP1/GIP phosphatase activity, whereas PKCalpha (zeige PKCa Antikörper)-phosphorylated BG21 inhibited its activity, suggesting a potential role of BG21 as a molecular switch ("quick-brake mechanism") on SCP1/GIP.

  10. Myelin basic protein cleaves cell adhesion molecule (zeige MCAM Antikörper) L1 and promotes neuritogenesis and cell survival.

Myelin Basic Protein (MBP) Antigen-Profil

Protein Überblick

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.

Genbezeichner und Symbole assoziert mit MBP

  • myelin basic protein a (mbpa) Antikörper
  • myelin basic protein (mbp) Antikörper
  • myelin basic protein (MBP) Antikörper
  • myelin basic protein (Mbp) Antikörper
  • C76307 Antikörper
  • cb274 Antikörper
  • fj33b11 Antikörper
  • golli-mbp Antikörper
  • Hmbpr Antikörper
  • mbp Antikörper
  • Mbps Antikörper
  • MGC115135 Antikörper
  • mld Antikörper
  • R75289 Antikörper
  • shi Antikörper
  • wu:fj33b11 Antikörper
  • wu:fq15b02 Antikörper
  • zgc:136630 Antikörper

Bezeichner auf Proteinebene für MBP

myelin basic protein , myelin A1 protein , myelin membrane encephalitogenic protein , 20 kDa microtubule-stabilizing protein , microtubule-stabilizing protein , Golli-Mbp; myelin basic protein , Golli-Mbp; myelin basic protein; myelin basic protein S , MBP S , myelin basic protein Golli-mbp , myelin basic protein S , myelin deficient , shiverer , Golli-mbp

GENE ID SPEZIES
326281 Danio rerio
549346 Xenopus (Silurana) tropicalis
734401 Xenopus laevis
4155 Homo sapiens
414286 Sus scrofa
618684 Bos taurus
101109407 Ovis aries
100731253 Cavia porcellus
396217 Gallus gallus
24547 Rattus norvegicus
17196 Mus musculus
476160 Canis lupus familiaris
399102 Xenopus laevis
455522 Pan troglodytes
100174122 Pongo abelii
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