Mycn (MYCN) ELISA Kits

MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. Zusätzlich bieten wir Ihnen MYCN Antikörper (96) und MYCN Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
MYCN 4613 P04198
MYCN 298894 Q63379
MYCN 18109 P03966
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Top MYCN ELISA Kits auf antikoerper-online.de

Showing 5 out of 6 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
772,39 €
Details
Ratte 0.312-20 ng/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
716,57 €
Details
Ratte
0.312-20 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
860,54 €
Details
Maus
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
860,54 €
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Huhn
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
1.013,20 €
Details

Weitere ELISA Kits für MYCN Interaktionspartner

Human Mycn (MYCN) Interaktionspartner

  1. our results identify DOT1L (zeige DOT1L ELISA Kits) as a novel cofactor in N-Myc-mediated transcriptional activation of target genes and neuroblastoma (zeige ARHGEF16 ELISA Kits) oncogenesis. Furthermore, they characterize DOT1L (zeige DOT1L ELISA Kits) inhibitors as novel anticancer agents against MYCN-amplified neuroblastoma (zeige ARHGEF16 ELISA Kits).

  2. CCCTC-binding factor (CTCF (zeige CTCF ELISA Kits)) targets the binding sites within MYCN promoter to facilitate its expression in neuroblastoma (zeige ARHGEF16 ELISA Kits) (NB) cells.

  3. PAX3 (zeige PAX3 ELISA Kits)-FOXO1 (zeige FOXO1 ELISA Kits) collaborates with MYCN during early rhabdomyosarcoma (RMS) tumourigenesis to dysregulate proliferation and inhibit myogenic differentiation and cell death.

  4. The findings reveal a PLK1 (zeige PLK1 ELISA Kits)-Fbw7 (zeige FBXW7 ELISA Kits)-Myc (zeige MYC ELISA Kits) signaling circuit that underlies tumorigenesis and validate PLK1 (zeige PLK1 ELISA Kits) inhibitors, alone or with Bcl2 (zeige BCL2 ELISA Kits) antagonists, as potential effective therapeutics for MYC (zeige MYC ELISA Kits)-overexpressing cancers.

  5. Results show that N-Myc overexpression leads to the development of poorly differentiated, invasive prostate cancer that is molecularly similar to human NEPC.

  6. Rac (zeige AKT1 ELISA Kits) activity may be an important determinant of metastatic capability in subsets of neuroblastoma (zeige ARHGEF16 ELISA Kits) cells lacking MYCN amplification.

  7. MYCN Gene Amplification is associated with Neuroblastoma (zeige ARHGEF16 ELISA Kits).

  8. MYCN overexpression combined with activated anaplastic lymphoma kinase (ALK (zeige ALK ELISA Kits)) is sufficient to induce neuroblastoma (zeige ARHGEF16 ELISA Kits) (NB) in mouse sympathoadrenal cells

  9. MYCN amplification can be heterogeneous between tumor sites, during tumor progression or following treatment, challenging the notion that MYCN copy number does not change for a particular neuroblastoma (zeige ARHGEF16 ELISA Kits).

  10. High MycN expression is associated with low radiosensitivity in neuroblastoma (zeige ARHGEF16 ELISA Kits).

Mouse (Murine) Mycn (MYCN) Interaktionspartner

  1. a Mycn target gene encoding the miR (zeige MLXIP ELISA Kits) cluster miR-17~92, while most retinoblastomas reemerged without clear genetic alterations in either Mycn or known Mycn targets. This Rb/MYCN model recapitulates key genetic driver alterations seen in human retinoblastoma and reveals the emergence of MYCN independence in an initially MYCN-driven tumor.

  2. The findings reveal a PLK1 (zeige PLK1 ELISA Kits)-Fbw7 (zeige FBXW7 ELISA Kits)-Myc (zeige MYC ELISA Kits) signaling circuit that underlies tumorigenesis and validate PLK1 (zeige PLK1 ELISA Kits) inhibitors, alone or with Bcl2 (zeige BCL2 ELISA Kits) antagonists, as potential effective therapeutics for MYC (zeige MYC ELISA Kits)-overexpressing cancers.

  3. ALKR1275Q cooperated with MYCN in the development of aggressive NB, possibly by downregulating the expression of ECM (zeige MMRN1 ELISA Kits)/BM-associated genes and by conferring malignant potentials to MYCN-expressing cells.

  4. Reuslts show that N-Myc overexpression leads to the development of poorly differentiated, invasive prostate cancer that is molecularly similar to human NEPC.

  5. Thus, this synergistic effect of ZD55-shMYCN in combination with doxorubicin provides a novel therapy strategy for doxorubicin-resistant neuroblastoma (zeige ARHGEF16 ELISA Kits), and is a promising approach for further clinical development.

  6. demonstrate a critical link between Myc (zeige MYC ELISA Kits)/Mycn gene activity and glycolysis in spermatogonial stem cell self-renewal

  7. Loss of N-myc significantly impairs the Sonic hedgehog (zeige SHH ELISA Kits) signaling pathway and disrupts the expression of cell cycle effectors with a significant reduction of Ccnd2 (zeige CCND2 ELISA Kits).

  8. Study shows that ground-state embryonic stem cells express low Myc (zeige MYC ELISA Kits) levels. Deletion of both c-myc (zeige MYC ELISA Kits) and N-myc activity strongly decreases transcription, splicing, and protein synthesis, leading to proliferation arrest; process is reversible and occurs without affecting pluripotency, suggesting that Myc (zeige MYC ELISA Kits)-depleted stem cells enter a state of dormancy.

  9. MYCN overexpression is not sufficient for these cells to form tumors in nude mice

  10. ITGA4 (zeige ITGA4 ELISA Kits) expression enhances metastasis in MYCN low neuroblastoma (zeige ARHGEF16 ELISA Kits).

MYCN Antigen-Profil

Beschreibung des Gens

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.

Genbezeichner und Symbole assoziert mit Mycn (MYCN) ELISA Kits

  • olfactory receptor, family 8, subfamily S, member 1-like (LOC515887) Antikörper
  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN) Antikörper
  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (Mycn) Antikörper
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (MYCN) Antikörper
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) (MYCN) Antikörper
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) (Mycn) Antikörper
  • bHLHe37 Antikörper
  • c-nmyc Antikörper
  • MODED Antikörper
  • MYCNOT Antikörper
  • N-myc Antikörper
  • Nmuc1 Antikörper
  • Nmyc Antikörper
  • Nmyc-1 Antikörper
  • Nmyc1 Antikörper
  • ODED Antikörper

Bezeichner auf Proteinebene für Mycn (MYCN) ELISA Kits

N-myc proto-oncogene protein , class E basic helix-loop-helix protein 37 , neuroblastoma MYC oncogene , neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene , oncogene NMYC , pp65/67 , v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived , v-myc myelocytomatosis viral related oncogene, neuroblastoma derived , Avian myelocytomatosis viral (v-myc) related oncogene neuroblastoma derived (Nmyc) , Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc) , N-myc protein , neuroblastoma myc-related oncogene 1

GENE ID SPEZIES
515887 Bos taurus
4613 Homo sapiens
298894 Rattus norvegicus
421948 Gallus gallus
482978 Canis lupus familiaris
18109 Mus musculus
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