anti-Mutated in Colorectal Cancers (MCC) Antikörper

MCC is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. Zusätzlich bieten wir Ihnen MCC Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MCC 4163 P23508
MCC 328949  
MCC 307449  
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Top anti-MCC Antikörper auf antikoerper-online.de

Showing 10 out of 70 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert IHC (f), IF, IP, WB Western blot analysis of MCC on a human endothelial cell lysate. Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of the anti- MCC antibody. Immunofluorescence staining of human endothelial cells. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$154.07
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using MCC, antibody at 1:250 dilution. WB Image Sample (30 ug of whole cell lysate) A: IMR32 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert WB MCC Antibody (Center)  western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the MCC antibody detected the MCC protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert WB Western blot analysis of MCC over-expressed 293 cell line, cotransfected with MCC Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of MCC expression in transfected 293T cell line by MCC monoclonal antibody (M01), clone 1A7. Lane 1: MCC transfected lysate(93.1 KDa). Lane 2: Non-transfected lysate. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Huhn Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$463.83
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: MCC Antibody [NBP2-17236] - Immunohistochemical analysis of paraffin-embedded Colon ca, using antibody at 1:250 dilution. Western Blot: MCC Antibody [NBP2-17236] - Sample (30 ug of whole cell lysate) A: IMR32 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details
Human Kaninchen Alexa Fluor 555 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Alexa Fluor 488 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

MCC Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-MCC Antikörper

  1. Human Monoclonal MCC Primary Antibody für IHC (f), IF - ABIN968147 : Ashton-Rickardt, Wyllie, Bird, Dunlop, Steel, Morris, Piris, Romanowski, Wood, White: MCC, a candidate familial polyposis gene in 5q.21, shows frequent allele loss in colorectal and lung cancer. in Oncogene 1991 (PubMed)
    Show all 5 Pubmed References

Weitere Antikörper gegen MCC Interaktionspartner

Zebrafish Mutated in Colorectal Cancers (MCC) Interaktionspartner

  1. The PDZ domain protein (zeige INADL Antikörper) Mcc is a novel effector of non-canonical Wnt (zeige WNT2 Antikörper) signaling during convergence and extension in zebrafish.

Human Mutated in Colorectal Cancers (MCC) Interaktionspartner

  1. Our results indicate that in sharp contrast to its tumor suppressive role in colorectal cancer, MCC functions as an oncogene (zeige RAB1A Antikörper) in B cells

  2. cytoplasmic MCC-DBC1 interaction sequesters DBC1 away from the nucleus, thereby removing a brake on DBC1 nuclear targets, such as SIRT1 (zeige SIRT1 Antikörper)

  3. targeted by miR (zeige MLXIP Antikörper)-494, which is overexpressed in hepatocellular carcinoma

  4. MCC regulates lamellipodia formation by binding to Scrib (zeige SCRIB Antikörper) and its downstream partner Myosin-IIB (zeige MYH10 Antikörper) in a multiprotein complex.

  5. we have shown that promoter methylation of the APC (zeige APC Antikörper) gene does not extend to the neighbouring MCC gene in lung cancer, but LOH is found at both loci.

  6. Promoter methylated MCC is associated with inflammatory bowel disease in colorectal cancer.

  7. MCC is a nuclear, beta-catenin-interacting protein (zeige CTNNBIP1 Antikörper) that can act as a potential tumor suppressor in the serrated colorectal cancer pathway by inhibiting Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signal transduction.

  8. Results identify MCC as a potential scaffold protein (zeige HOMER1 Antikörper) regulating cell movement and able to bind Scrib (zeige SCRIB Antikörper), beta-catenin (zeige CTNNB1 Antikörper) and NHERF1 (zeige SLC9A3R1 Antikörper)/2.

Mouse (Murine) Mutated in Colorectal Cancers (MCC) Interaktionspartner

  1. Our results indicate that in sharp contrast to its tumor suppressive role in colorectal cancer, MCC functions as an oncogene (zeige RAB1A Antikörper) in B cells

MCC Antigen-Profil

Protein Überblick

This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit MCC

  • mutated in colorectal cancers (MCC) Antikörper
  • mutated in colorectal cancers (mcc) Antikörper
  • mutated in colorectal cancers (Mcc) Antikörper
  • D18Ertd451e Antikörper
  • E330037C19 Antikörper
  • MCC Antikörper
  • MCC1 Antikörper
  • RGD1561988 Antikörper

Bezeichner auf Proteinebene für MCC

mutated in colorectal cancers , colorectal mutant cancer protein

GENE ID SPEZIES
100064404 Equus caballus
415603 Gallus gallus
462002 Pan troglodytes
694270 Macaca mulatta
100015680 Monodelphis domestica
100216150 Xenopus (Silurana) tropicalis
100354734 Oryctolagus cuniculus
100473268 Ailuropoda melanoleuca
100537329 Danio rerio
4163 Homo sapiens
328949 Mus musculus
307449 Rattus norvegicus
611208 Canis lupus familiaris
616704 Bos taurus
Ausgewählte Anbieter für anti-MCC (MCC) Antikörper
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