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Involved in meiotic recombination. Zusätzlich bieten wir Ihnen MSH4 Antikörper (39) und viele weitere Produktgruppen zu diesem Protein an.
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inactivation of MSH4 in germ cells may have played a role in the acquisition of additional TP53 and LATS1 germline mutations in a Li-Fraumeni family
hMSH4 interacts with HDAC3 (zeige HDAC3 Proteine).
Our current study has revealed a role for hMSH4 in the maintenance of genomic stability by suppressing NHEJ-mediated DSB repair.
mutation analysis of SYCP3 (zeige SYCP3 Proteine), DNMT3L (zeige TRDMT1 Proteine) and MSH4 in patients with maturation arrest of spermatogenesis and couples with recurrent miscarriages
Mutations within the hMLH1 and hPMS2 subunits of the human MutLalpha mismatch repair factor affect its ATPase activity, but not its ability to interact with hMutSalpha
The different properties associated with these two hMSH5 (zeige MSH5 Proteine) variants underscore the potential functional diversity of the human hMSH5 (zeige MSH5 Proteine) gene.
the GPS2 (zeige GPS2 Proteine) might function in concert with hMSH4-hMSH5 (zeige MSH5 Proteine) during the process of homologous recombination.
A review of the properties and functional roles of MSH4.
Dimerization of MSH4 and MSH5 (zeige MSH5 Proteine) facilitates their nuclear localization suggesting that dimerization may regulate the intracellular trafficking of these proteins.
Data have identified the interaction region between the individual subunits of hMSH4-hMSH5 that are likely involved in clamp formation and show that each subunit of the heterodimer binds ATP.
Study suggests that the dynamic interchromosomal (intergenic) trans-splicing generates functional diversity of the mouse Msh4 gene.
Involved in meiotic recombination. Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis.
mutS protein homolog 4
, mutS homolog 4 (E. coli)
, mutS protein homolog 4-like
, mutS homolog 4
, MutS homolog 4 variant iota 1
, MutS homolog 4 variant theta 1