anti-Mitofusin 1 (MFN1) Antikörper

The protein encoded by MFN1 is a mediator of mitochondrial fusion. Zusätzlich bieten wir Ihnen Mitofusin 1 Proteine (11) und Mitofusin 1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MFN1 55669 Q8IWA4
MFN1 67414 Q811U4
MFN1 192647 Q8R4Z9
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Showing 10 out of 137 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-MFN1 Antibody Titration: 0.2-1 ug/mlPositive Control: Human Placenta WB Suggested Anti-MFN1  Antibody Titration: 0.2-1 µg/mL  Positive Control: Human Placenta 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, WB MFN1 Antibody (Center) western blot analysis in Jurkat cell line lysates (35µg/lane).This demonstrates the MFN1 antibody detected the MFN1 protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert FACS, IF (p), IHC (p), WB Rat brain lysates probed with Anti-Mfn1 Polyclonal Antibody  at 1:5000 90min in 37˚C. RSC96 probed with Mfn1 Polyclonal Antibody, Unconjugated  at 1:100 for 30 minutes followed by incubation with a conjugated secondary (PE Conjugated) (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
315,94 €
Details
Maus Maus Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Mitofusin 1 Antibody (11E9-1H12) [NBP1-71775] - Mitofusin 1 antibody was tested in 3T3 cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Immunohistochemistry-Paraffin: Mitofusin 1 Antibody (11E9-1H12) [NBP1-71775] - Analysis of Mitofusin-1 in mouse liver. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Human Kaninchen Unkonjugiert WB Anti- Mitofusin 1 Picoband antibody, Western blotting All lanes: Anti Mitofusin 1  at 0.5ug/ml Lane 1: Rat Cardiac Muscle Tissue Lysate at 50ug Lane 2: Rat Kidney Tissue Lysate at 50ug Lane 3: Mouset Cardiac Muscle Tissue Lysate at 50ug Lane 4: HELA Whole Cell Lysate at 40ug Lane 5: COLO320 Whole Cell Lysate at 40ug Lane 6: A549 Whole Cell Lysate at 40ug Predicted bind size: 84KD Observed bind size: 84KD 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Mitofusin 1 Antibody [NBP1-51841] - Mfn-1 expressed in mouse neural stem cells. Image from verified customer review. Immunocytochemistry/Immunofluorescence: Mitofusin 1 Antibody [NBP1-51841] - Mitofusin-1 antibody was tested in HeLa cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
Details
Human Maus Unkonjugiert IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
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Human Maus Unkonjugiert WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details
Human Maus Unkonjugiert RNAi, ELISA, WB MFN1 monoclonal antibody (M04), clone 3C9 Western Blot analysis of MFN1 expression in HeLa Western blot analysis of MFN1 over-expressed 293 cell line, cotransfected with MFN1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with MFN1 monoclonal antibody (M04), clone 3C9. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Hund Ziege Unkonjugiert IHC (p) Adrenal, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
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MFN1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Mitofusin 1 Antikörper

  1. Human Monoclonal MFN1 Primary Antibody für RNAi, ELISA - ABIN527615 : Zanna, Ghelli, Porcelli, Karbowski, Youle, Schimpf, Wissinger, Pinti, Cossarizza, Vidoni, Valentino, Rugolo, Carelli: OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion. in Brain : a journal of neurology 2008 (PubMed)
    Zeige alle 14 Referenzen für 527615

  2. Mouse (Murine) Monoclonal MFN1 Primary Antibody für ICC, IF - ABIN4334757 : White, Puppa, Sato, Gao, Price, Baynes, Kostek, Matesic, Carson: IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the ApcMin/+ mouse. in Skeletal muscle 2012 (PubMed)
    Zeige alle 7 Referenzen für 4334757

  3. Human Polyclonal MFN1 Primary Antibody für ICC, IF - ABIN4334755 : Miller, Knaub, Olivera-Fragoso, Keller, Balasubramaniam, Watson, Reusch: Nitric oxide regulates vascular adaptive mitochondrial dynamics. in American journal of physiology. Heart and circulatory physiology 2013 (PubMed)
    Zeige alle 4 Referenzen für 4334755

  4. Human Polyclonal MFN1 Primary Antibody für FACS, IF (p) - ABIN670071 : Lou, Guan, Liu, Liu, Zhang, Pan, Pei: The influence of chronic fluorosis on mitochondrial dynamics morphology and distribution in cortical neurons of the rat brain. in Archives of toxicology 2013 (PubMed)
    Zeige alle 3 Referenzen für 670071

  5. Cow (Bovine) Polyclonal MFN1 Primary Antibody für WB - ABIN2787347 : Bonala, McFarlane, Ang, Lim, Lee, Chua, Lokireddy, Sreekanth, Leow, Meng, Shyong, Lee, Gluckman, Sharma, Kambadur: Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity. in Molecular endocrinology (Baltimore, Md.) 2013 (PubMed)
    Zeige alle 2 Referenzen für 2787347

  6. Human Polyclonal MFN1 Primary Antibody für EIA, WB - ABIN953454 : Perumalsamy, Nagala, Sarin: Notch-activated signaling cascade interacts with mitochondrial remodeling proteins to regulate cell survival. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Zeige alle 2 Referenzen für 953454

Weitere Antikörper gegen Mitofusin 1 Interaktionspartner

Cow (Bovine) Mitofusin 1 (MFN1) Interaktionspartner

  1. The results showed that high level of Mfn1 expression significantly improved the embryo development rates by increasing ATP level and Deltapsim, while reducing H(2)O(2) generation.

Human Mitofusin 1 (MFN1) Interaktionspartner

  1. MFN1-positive expression could be seen mainly in ganglion cells after 1 week of minus lens intervention, and with time extension, more and more positive cells appeared in the rod-cone cell and bipolar cell layer, and this phenomenon could not be found in the normal control eyes.

  2. crystal structures of engineered human MFN1 containing the GTPase (zeige RACGAP1 Antikörper) domain and a helical domain during different stages of GTP (zeige AK3 Antikörper) hydrolysis; mechanistic model for MFN1-mediated mitochondrial tethering is proposed; results shed light on the molecular basis of mitochondrial fusion and mitofusin (zeige MFN2 Antikörper)-related human neuromuscular disorders

  3. These results suggest that MFN (zeige TLL1 Antikörper) tethers apposing membranes, likely through nucleotide-dependent dimerization.

  4. Improper transcriptional (in)activation of mitofusin-1 and dynamin-related protein 1 (zeige DNM1L Antikörper) during early in vitro embryo development is associated with a decrease in mitochondrial membrane potential and with embryo fragmentation.

  5. A fine balance of Mfn1 levels is maintained by MARCH5 (zeige MARCH5 Antikörper)-mediated quality control on acetylated Mfn1.

  6. miR (zeige MLXIP Antikörper)-19b targets 3'UTR (zeige UTS2R Antikörper) sequences of Mfn1 genes inhibit the expression of Mfn1

  7. In a amyotrophic lateral sclerosis transgenic mouse model, Mfn1 is significantly increased in spinal cord.

  8. A novel role for the endoplasmic reticulum-associated Gp78 (zeige AMFR Antikörper) ubiquitin ligase and the Mfn1 mitochondrial fusion factor in mitophagy.

  9. Knock-out of mitofusin (zeige MFN2 Antikörper) protein Mfn1 increased the frequency of mitochondrial fission with increased lifetime of unpaired events whereas deletion of both Mfn1 and Mfn2 (zeige MFN2 Antikörper) resulted in an instable dynamics.

  10. These results collectively suggest a role for Mfn1 in regulating the activation of Bax (zeige BAX Antikörper) on the outer mitochondrial membrane in a GTPase (zeige RACGAP1 Antikörper)-dependent manner.

Mouse (Murine) Mitofusin 1 (MFN1) Interaktionspartner

  1. We found that mouse embryonic fibroblasts lacking Mfn2 (zeige MFN2 Antikörper) have altered lipid droplet morphology. However, triacylglycerol biosynthesis was not dependent on ER-mitochondrial tethering mediated by mitofusins. Lastly, Mfn2 (zeige MFN2 Antikörper) does not have a role in adipocyte differentiation.

  2. MFN1 deficiency leads to defects in mitochondrial activity and male infertility.

  3. Report exposes a novel role for Shh (zeige SHH Antikörper) in regulating mitochondrial dynamics and rescue the metabolic profile of tumor cells through regulation of mitofusin 1 and 2.

  4. Ablating Mfn1 eliminates the cardiac-related lethality of Mff (zeige MFF Antikörper) knockout mice.

  5. Data suggest that mitochondrial fusion and fission events are regulated by four GTPases: Mfn1, Mfn2 (zeige MFN2 Antikörper), OPA1 (optic atrophy 1 (zeige OPA1 Antikörper) protein), and Drp1 (dynamin 1-like protein (zeige DNM1L Antikörper)). [REVIEW]

  6. Authors present evidence that metabolically challenged mitochondria undergo active fusion to suppress oxidative stress. In response to glucose starvation, mitofusin 1 (MFN1) becomes associated with the protein deacetylase HDAC6 (zeige HDAC6 Antikörper).

  7. These findings suggest that mitochondrial impairment is a very early event in Alzheimer disease pathogenesis and abnormal expression of Mfn1 and Mfn2 (zeige MFN2 Antikörper) caused by excessive intracellular Abeta (zeige APP Antikörper) is the possible molecular mechanism.

  8. Data identify MFN1 as an ERK (zeige EPHB2 Antikörper) target to modulate mitochondrial shape and apoptosis.

  9. A fine balance of Mfn1 levels is maintained by MARCH5 (zeige MARCH5 Antikörper)-mediated quality control on acetylated Mfn1.

  10. Mitochondrial shape governs BAX (zeige BAX Antikörper)-induced membrane permeabilization and apoptosis via Mfn1.

Mitofusin 1 (MFN1) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.

Genbezeichner und Symbole assoziert mit anti-Mitofusin 1 (MFN1) Antikörper

  • mitofusin 1b (mfn1b) Antikörper
  • mitofusin 1 (MFN1) Antikörper
  • mitofusin 1 (mfn1) Antikörper
  • mitofusin 1 (Mfn1) Antikörper
  • 2310002F04Rik Antikörper
  • 6330416C07Rik Antikörper
  • D3Ertd265e Antikörper
  • Fzo1b Antikörper
  • hfzo1 Antikörper
  • hfzo2 Antikörper
  • HR2 Antikörper
  • MFN1 Antikörper
  • MFN2 Antikörper
  • mitofusin-1 Antikörper
  • mKIAA4032 Antikörper
  • zgc:66150 Antikörper

Bezeichner auf Proteinebene für anti-Mitofusin 1 (MFN1) Antikörper

mitofusin 1 , mitofusin-1 , mitofusin 2 , mitofusin-1-like , fzo homolog , mitochondrial transmembrane GTPase FZO-2 , mitochondrial transmembrane GTPase Fzo-1 , putative transmembrane GTPase , transmembrane GTPase MFN1 , mitochondrial transmembrane GTPase FZO1B

GENE ID SPEZIES
393620 Danio rerio
424973 Gallus gallus
460861 Pan troglodytes
488086 Canis lupus familiaris
495314 Xenopus laevis
515180 Bos taurus
548943 Xenopus (Silurana) tropicalis
100394906 Callithrix jacchus
100586660 Nomascus leucogenys
55669 Homo sapiens
67414 Mus musculus
192647 Rattus norvegicus
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