Mitochondrially Encoded NADH Dehydrogenase 5 Proteine (MT-ND5)

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Zusätzlich bieten wir Ihnen Mitochondrially Encoded NADH Dehydrogenase 5 Antikörper (59) und Mitochondrially Encoded NADH Dehydrogenase 5 Kits (11) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MT-ND5 4540 P03915
MT-ND5 26202  
MT-ND5    
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 46 bis 51 Tage
5.743,80 €
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
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HOST_Escherichia coli (E. coli) Ratte His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
786,67 €
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HOST_Escherichia coli (E. coli) Ratte Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
975,60 €
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MT-ND5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human

Rat (Rattus)

Mouse (Murine)

Weitere Proteine zu Mitochondrially Encoded NADH Dehydrogenase 5 (MT-ND5) Interaktionspartnern

Human Mitochondrially Encoded NADH Dehydrogenase 5 (MT-ND5) Interaktionspartner

  1. The m.13565C>T mutation in MTND5 causes defects in both mitochondrial oxidative metabolism and mitochondrial calcium sequestration in a MELAS syndrome fibroblasts.

  2. Mitochondrially encoded NADH dehydrogenase subunit, complex I extracts energy from NADH, produced by the oxidation of sugars and fats, and traps the energy in a potential difference or voltage across the mitochondrial inner membrane.

  3. Study demonstrates a link between p53 (zeige TP53 Proteine) and Bcl-2 (zeige BCL2 Proteine) proteins as regulators of ROS (zeige ROS1 Proteine) production and cellular invasiveness, and reveals complex-I, especially ND5, as their functional target in lung tumor cells.

  4. Three mutations were significantly related to the presence of epilepsy. These mutations were found at the 8502, 11994, and 13,231 bp of mtDNA, which resulted in amino acid changes at the MT-ATP-8 (zeige MT-ATP8 Proteine), MT-ND4 (zeige MT-ND4 Proteine) and MT-ND5 genes.

  5. Point mutations m.10191T>C in mitochondrial ND3 gene, m.13513G>A in ND5 gene and m.14,453G>A in ND6 gene were detected in three Chinese children with Leigh synrome dur to complex I deficiency.

  6. Mitochondrial ND5 12338T>C variant is associated with maternally inherited hypertrophic cardiomyopathy in a Chinese pedigree

  7. Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression in association with EGFR (zeige EGFR Proteine) gene mutation.

  8. ND4 (zeige MT-ND4 Proteine) G11696A and ND5 T12338C mutation is likely associated with Leber's hereditary optic neuropathy in two Chinese families

  9. Patients with ND5*13513 G to A mutation may have a characteristic clinical course and ND5 *13513 G to A might be a preferential candidate mutation of Leigh syndrome.

  10. these results suggest that the MT-ND1 (zeige MT-ND1 Proteine) and MT-ND5 genes are mutational hotspots for Chinese families with suspected LHON lacking the common primary mutations.

Mitochondrially Encoded NADH Dehydrogenase 5 (MT-ND5) Protein Überblick

Protein Überblick

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Genbezeichner und Symbole assoziert mit MT-ND5

  • mitochondrial NADH-ubiquinone oxidoreductase chain 5 (mt:ND5)
  • mitochondrially encoded NADH dehydrogenase 5 (MT-ND5)
  • NADH dehydrogenase 5, mitochondrial (mt-Nd5)
  • NADH dehydrogenase subunit 5 (ND5)
  • NADH dehydrogenase subunit 5 (nad5)
  • NADH dehydrogenase, subunit 5 (nad5)
  • MTND5 Protein
  • NADH5 Protein

Bezeichner auf Proteinebene für MT-ND5

NADH dehydrogenase subunit 5

GENE ID SPEZIES
192478 Drosophila melanogaster
4540 Homo sapiens
26202 Rattus norvegicus
804484 Canis lupus familiaris
807642 Gallus gallus
808511 Sus scrofa
808224 Oryctolagus cuniculus
2565703 Caenorhabditis elegans
3371313 Arabidopsis thaliana
808209 Branchiostoma lanceolatum
1734025 Acanthamoeba castellanii
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