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Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Zusätzlich bieten wir Ihnen Mitochondrially Encoded NADH Dehydrogenase 5 Antikörper (59) und Mitochondrially Encoded NADH Dehydrogenase 5 Kits (12) und viele weitere Produktgruppen zu diesem Protein an.
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FASTKD4 (zeige TBRG4 Proteine) is required to promote expression of ND5. FASTKD4 (zeige TBRG4 Proteine) may promote processing of ND5-CYB (zeige CSTB Proteine) precursor or it may stabilize multiple mature RNAs including ND5.
The m.13565C>T mutation in MTND5 causes defects in both mitochondrial oxidative metabolism and mitochondrial calcium sequestration in a MELAS syndrome fibroblasts.
Mitochondrially encoded NADH dehydrogenase subunit, complex I extracts energy from NADH, produced by the oxidation of sugars and fats, and traps the energy in a potential difference or voltage across the mitochondrial inner membrane.
Study demonstrates a link between p53 (zeige TP53 Proteine) and Bcl-2 (zeige BCL2 Proteine) proteins as regulators of ROS (zeige ROS1 Proteine) production and cellular invasiveness, and reveals complex-I, especially ND5, as their functional target in lung tumor cells.
Three mutations were significantly related to the presence of epilepsy. These mutations were found at the 8502, 11994, and 13,231 bp of mtDNA, which resulted in amino acid changes at the MT-ATP-8 (zeige MT-ATP8 Proteine), MT-ND4 (zeige MT-ND4 Proteine) and MT-ND5 genes.
Point mutations m.10191T>C in mitochondrial ND3 gene, m.13513G>A in ND5 gene and m.14,453G>A in ND6 gene were detected in three Chinese children with Leigh synrome dur to complex I deficiency.
Mitochondrial ND5 12338T>C variant is associated with maternally inherited hypertrophic cardiomyopathy in a Chinese pedigree
Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression in association with EGFR (zeige EGFR Proteine) gene mutation.
ND4 (zeige MT-ND4 Proteine) G11696A and ND5 T12338C mutation is likely associated with Leber's hereditary optic neuropathy in two Chinese families
Patients with ND5*13513 G to A mutation may have a characteristic clinical course and ND5 *13513 G to A might be a preferential candidate mutation of Leigh syndrome.
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
NADH dehydrogenase subunit 5