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Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Zusätzlich bieten wir Ihnen Microtubule-Associated Protein, RP/EB Family, Member 3 Antikörper (66) und Microtubule-Associated Protein, RP/EB Family, Member 3 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.
One candidate pathway coupling actin filaments to microtubules consists of the actin filament-binding protein drebrin (zeige DBN1 ELISA Kits) and the microtubule-binding +TIP protein EB3. This pathway is regulated proximally by cyclin-dependent kinase 5 (zeige CDK5 ELISA Kits) phosphorylation of drebrin (zeige DBN1 ELISA Kits) but the upstream elements in the pathway have yet to be identified.
EB1 (zeige MAPRE2 ELISA Kits) and EB3 thus affect multiple interphase processes and have a major impact on microtubule minus end organization.
Findings show that co-ordination of dynamic microtubules and actin filaments by the drebrin (zeige DBN1 ELISA Kits)/EB3 pathway drives prostate cancer cell invasion and is therefore implicated in disease progression.
Aptamers binding to human EB1 (zeige MAPRE2 ELISA Kits) and EB3, which have sequence requirements similar to but distinct from each other and from Drosophila EB1 (zeige MAPRE2 ELISA Kits), were identified.
EB1 (zeige MAPRE2 ELISA Kits) and EB3 proteins are obligatory dimers.
Findings suggest that methylation-associated down-regulation of EBF3 and IRX1 (zeige IRX3 ELISA Kits) genes may play an important role in a pathogenic effect of TGF-beta (zeige TGFB1 ELISA Kits) on RASFs.
Daughter cell adhesion and cytokinesis completion are spatially regulated by distinct states of EB3 phosphorylation on serine 176 by Aurora B (zeige AURKB ELISA Kits).
decreasing the drebrin E (zeige DBN1 ELISA Kits) levels disrupted the normal subapical F-actin-myosin-IIB (zeige MYH10 ELISA Kits)-betaII-spectrin network and the apical accumulation of EB3, a microtubule-plus-end-binding protein
VE-cadherin (zeige CDH5 ELISA Kits) outside-in signaling regulates cytosolic calcium homeostasis and EB3 phosphorylation.
Data indicated that EB1 (zeige MAPRE2 ELISA Kits) and EB3 interact with proteins implicated in MT minus-end anchoring or vesicular trafficking to the cilia base, suggesting that EB1 (zeige MAPRE2 ELISA Kits) and EB3 promote ciliogenesis by facilitating such trafficking.
EB3 binds to IP3 receptors, promotes IP3R (zeige ITPR1 ELISA Kits) clustering and Ca2 (zeige CA2 ELISA Kits)+ signals in endothelial cells.
MAP1B (zeige MAP1B ELISA Kits) interacts directly with EB1 (zeige MAPRE1 ELISA Kits) and EB3 (EBs), two core 'microtubule plus-end tracking proteins' ( TIPs), and sequesters them in the cytosol of developing neuronal cells.
DDA3 (zeige PSRC1 ELISA Kits) is a novel microtubule-associated protein (zeige SPAG5 ELISA Kits) that binds to EB3, and results implicate DDA3 (zeige PSRC1 ELISA Kits) and EB3 in the beta-catenin (zeige CTNNB1 ELISA Kits)-mediated growth signaling.
Two +TIPs, CLIP-170 (zeige CLIP1 ELISA Kits) and end-binding protein 3 (EB3), turn over rapidly on MT ends. Diffusion of CLIP-170 (zeige CLIP1 ELISA Kits) and EB3 appears to be rate limiting for their binding to MT plus ends.
Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity).
microtubule-associated protein, RP/EB family, member 3
, APC binding protein
, EB1 protein family member 3
, end-binding protein 3
, microtubule-associated protein RP/EB family member 3