anti-Metastasis Associated in Colon Cancer 1 (MACC1) Antikörper

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Zusätzlich bieten wir Ihnen MACC1 Kits (10) und MACC1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MACC1 346389 Q6ZN28
MACC1 238455  
MACC1 314539  
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Top anti-MACC1 Antikörper auf antikoerper-online.de

Showing 10 out of 40 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Western blot analysis of MACC1 expression in HEK293T (A), H9C2 (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human stomach tissue labeled with Anti-MACC1Polyclonal Antibody, Unconjugated (ABIN706526) followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-MACC1 Polyclonal Antibody, Unconjugated (ABIN706526) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
315,94 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), SimWes Simple Western: MACC1 Antibody [NBP1-89352] - Simple Western lane view shows a specific band for MACC1 in 0.2 mg/ml of RT-4 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. Immunohistochemistry-Paraffin: MACC1 Antibody [NBP1-89352] - Staining of human endometrium shows strong cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: MACC1 Antibody [NBP1-89351] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10.Lane 2: Human cell line A-431 Immunohistochemistry-Paraffin: MACC1 Antibody [NBP1-89351] - Staining of human duodenum shows cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
357,50 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
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Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
426,22 €
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Human Kaninchen Cy5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
426,22 €
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Human Kaninchen Cy7 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
426,22 €
Details
Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
426,22 €
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MACC1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-MACC1 Antikörper

  1. Human Polyclonal MACC1 Primary Antibody für IF (p), IHC (p) - ABIN706526 : Sun, Li, Dai, Tan, Zhao, Li, Wang: Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells. in Molecular medicine reports 2015 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal MACC1 Primary Antibody für IHC, IHC (p) - ABIN4332277 : Ge, Meng, Zhou, Zhang, Ding: Positive MACC1 expression correlates with invasive behaviors and postoperative liver metastasis in colon cancer. in International journal of clinical and experimental medicine 2015 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal MACC1 Primary Antibody für ELISA, IHC - ABIN5582886 : Liu, Pan, Guo, Wu, Guo, Peng, Wu, Zuo: A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway. in Journal of hematology & oncology 2016 (PubMed)

  4. Human Polyclonal MACC1 Primary Antibody für IHC, IHC (p) - ABIN4332275 : Hagemann, Fuchs, Monoranu, Herrmann, Smith, Hohmann, Grabiec, Kessler, Dehghani, Löhr, Ernestus, Vince, Stein: Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis. in Neuro-oncology 2013 (PubMed)

Weitere Antikörper gegen MACC1 Interaktionspartner

Human Metastasis Associated in Colon Cancer 1 (MACC1) Interaktionspartner

  1. Metastasis-associated in colon cancer 1 is expressed at early stages of colorectal oncogenesis within the affected colonic tissue in colorectal cancer patient cohort.

  2. MACC1 is a key driver and prognostic biomarker for cancer progression and metastasis in a large variety of solid tumor types, particularly colorectal cancer (CRC (zeige CALR Antikörper)). Data suggest that some small molecules with antineoplastic activity inhibit MACC1 transcription in CRC (zeige CALR Antikörper) and prevent liver metastasis in CRC (zeige CALR Antikörper); lovastatin and rottlerin are the antineoplastic agents used here.

  3. MACC1 regulates Fas (zeige FAS Antikörper) mediated apoptosis through STAT1 (zeige STAT1 Antikörper)/3 - Mcl-1 (zeige MCL1 Antikörper) signaling in solid cancers.

  4. High expression of MACC1 is associated with non-small cell lung cancer.

  5. MACC1 down-regulation suppresses endometrial carcinoma cell proliferation.

  6. SPON2 (zeige SPON2 Antikörper) is a transcriptional target of the metastasis gene MACC1. SPON2 (zeige SPON2 Antikörper) induces cell motility in vitro and CRC (zeige CALR Antikörper) metastasis in mice. In patients, SPON2 (zeige SPON2 Antikörper) serves as prognostic indicator for CRC (zeige CALR Antikörper) metastasis and survival, and might represent a promising target for therapeutic approaches.

  7. High MACC1 expression is associated with Angiogenesis and recurrence in Gastric Cancer.

  8. Elevated Orai1 (zeige ORAI1 Antikörper) and STIM1 (zeige STIM1 Antikörper) expressions upregulate MACC1 expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer.

  9. Data show that metastasis-associated in colon cancer-1 (MACC1) and monocarboxylate transporter 1 (MCT1) are highly expressed in gastric cancer indicating poor prognosis.

  10. A novel role of MACC1 in gastric cancer cell lipogenesis.MACC1 and FASN (zeige FASN Antikörper) are positively correlated and responsible for the poor prognoses in gastric cancer patients.

Mouse (Murine) Metastasis Associated in Colon Cancer 1 (MACC1) Interaktionspartner

  1. Data suggest a critical role for MACC1 in lymphatic dissemination of GC, providing evidence that MACC1 upregulated VEGF-C/VEGF-D secretion to promote lymphangiogenesis via c-Met signaling.

  2. HGF, MACC1 and C-met genes involve into malignant cervical tumors occurrence, development and prognosis, and might become potential molecular target therapy site of cervical cancer

  3. MACC1 has a role in colorectal cancer and can be used for imaging in xenografts

  4. MACC1 will be useful for the identification of poor prognosis subjects with colorectal cancer and is a promising new target for intervention in metastasis formation.

MACC1 Antigen-Profil

Protein Überblick

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009

Genbezeichner und Symbole assoziert mit MACC1

  • metastasis associated in colon cancer 1 (MACC1) Antikörper
  • metastasis associated in colon cancer 1 (Macc1) Antikörper
  • 7a5 Antikörper
  • 4732474O15Rik Antikörper
  • Gm267 Antikörper
  • RGD1309838 Antikörper
  • SH3BP4L Antikörper

Bezeichner auf Proteinebene für MACC1

SH3 domain-containing protein 7a5 , metastasis-associated in colon cancer protein 1 , putative binding protein 7a5

GENE ID SPEZIES
346389 Homo sapiens
238455 Mus musculus
314539 Rattus norvegicus
521867 Bos taurus
Ausgewählte Anbieter für anti-MACC1 (MACC1) Antikörper
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