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anti-Metastasis Associated in Colon Cancer 1 (MACC1) Antikörper

MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Zusätzlich bieten wir Ihnen Metastasis Associated in Colon Cancer 1 Kits (7) und Metastasis Associated in Colon Cancer 1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MACC1 346389 Q6ZN28
MACC1 238455  
MACC1 314539  
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Showing 10 out of 35 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Immunohistochemistry of MACC1 in human liver tissue with this product at 2.5 μg/ml. Western blot analysis of MACC1 in mouse liver tissue lysate with this product at (A) 1 and (B) 2 μg/ml. 0.1 mg Anmelden zum Anzeigen 8 bis 10 Tage
357,50 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human stomach tissue labeled with Anti-MACC1Polyclonal Antibody, Unconjugated (ABIN706526) followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-MACC1 Polyclonal Antibody, Unconjugated (ABIN706526) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
277,90 €
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Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 12 Days
194,82 €
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Human Kaninchen Unkonjugiert WB Western blot analysis of MACC1 expression in HEK293T (A), H9C2 (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 7 bis 8 Tage
510,71 €
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis of MACC1 in mouse liver tissue lysate with MACC1 antibody at (A) 1 and (B) 2 µg/ml. 50 μg Anmelden zum Anzeigen 8 bis 10 Tage
517,00 €
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Human Kaninchen Unkonjugiert WB, ICC, IHC (p), IHC (fro) 100 μg Anmelden zum Anzeigen 7 bis 10 Tage
404,38 €
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Human Kaninchen Alexa Fluor 647 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 17 Tage
366,11 €
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Human Kaninchen Alexa Fluor 350 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 17 Tage
366,11 €
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Human Kaninchen Alexa Fluor 555 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 17 Tage
366,11 €
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Human Kaninchen Alexa Fluor 488 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 17 Tage
366,11 €
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MACC1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human , , , ,

Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Am meisten referenzierte anti-Metastasis Associated in Colon Cancer 1 Antikörper

  1. Human Polyclonal MACC1 Primary Antibody für EIA,IHC (p) - ABIN500214 : Boardman: Overexpression of MACC1 leads to downstream activation of HGF/MET and potentiates metastasis and recurrence of colorectal cancer. in Genome medicine 2009 (PubMed)
    Zeige alle 4 Referenzen für ABIN500214

  2. Human Polyclonal MACC1 Primary Antibody für WB,IHC (p) - ABIN706526 : Sun, Li, Dai, Tan, Zhao, Li, Wang: Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells. in Molecular medicine reports 2015 (PubMed)

Weitere Antikörper gegen Metastasis Associated in Colon Cancer 1 Interaktionspartner

Human Metastasis Associated in Colon Cancer 1 (MACC1) Interaktionspartner

  1. In renal cell carcinoma (zeige MOK Antikörper), positive MACC1 expression was found to significantly correlate with distant metastasis and TNM (zeige ODZ1 Antikörper) stage. patients with higher MACC1 expression had a significantly lower disease-free rate

  2. conclusion, high MACC1 expression may serve as a prognostic biomarker to guide individualized management in clinical practice for digestive system neoplasms.

  3. MACC1 promotes vasculogenic mimicry in gastric cancer by regulating the HGF/c-Met-TWIST1 (zeige TWIST1 Antikörper)/2 signaling pathway.

  4. MACC1 expression predicts survival outcome in colorectal cancer patients.

  5. These results suggested that MACC1 leads to a poor prognosis in HCC (zeige FAM126A Antikörper), partly by promoting proliferation via enhancement in glucose metabolism by HK2 (zeige HK2 Antikörper).

  6. our findings provide some novel insights into the role of MACC1 in breast cancer, indicating that it plays different roles in breast and several other cancers.

  7. MACC1 overexpression predicted worse prognosis after liver resection, which was attributed to the repression of HCC (zeige FAM126A Antikörper) cell apoptosis via a molecular mechanism in which MACC1 accelerated the activation of the HGF/c-MET/PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper) pathway

  8. MACC1 expression might be closely related to carcinogenesis, clinical biological behaviors, and prognosis of gallbladder adenocarcinoma.

  9. Silencing of MACC1 was found to enhance the apoptosis.

  10. Levels of circulating MACC1 transcripts in plasma of gastric cancer patients are of diagnostic value and are prognostic for patient survival.

Mouse (Murine) Metastasis Associated in Colon Cancer 1 (MACC1) Interaktionspartner

  1. Data suggest a critical role for MACC1 in lymphatic dissemination of GC, providing evidence that MACC1 upregulated VEGF-C/VEGF-D secretion to promote lymphangiogenesis via c-Met signaling.

  2. HGF, MACC1 and C-met genes involve into malignant cervical tumors occurrence, development and prognosis, and might become potential molecular target therapy site of cervical cancer

  3. MACC1 has a role in colorectal cancer and can be used for imaging in xenografts

  4. MACC1 will be useful for the identification of poor prognosis subjects with colorectal cancer and is a promising new target for intervention in metastasis formation.

Metastasis Associated in Colon Cancer 1 (MACC1) Antigen-Profil

Protein Überblick

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009

Genbezeichner und Symbole assoziert mit MACC1

  • metastasis associated in colon cancer 1 (MACC1) Antikörper
  • metastasis associated in colon cancer 1 (Macc1) Antikörper
  • 7a5 Antikörper
  • 4732474O15Rik Antikörper
  • Gm267 Antikörper
  • RGD1309838 Antikörper
  • SH3BP4L Antikörper

Bezeichner auf Proteinebene für MACC1

SH3 domain-containing protein 7a5 , metastasis-associated in colon cancer protein 1 , putative binding protein 7a5

GENE ID SPEZIES
346389 Homo sapiens
238455 Mus musculus
314539 Rattus norvegicus
521867 Bos taurus
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