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MTNR1A encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. Zusätzlich bieten wir Ihnen Melatonin Receptor 1A Antikörper (104) und Melatonin Receptor 1A Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.
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One single nucleotide polymorphism (SNP), rs713224, located near the brain-expressed melatonin receptor (MTNR1A) gene, was associated with the somatic complaints domain of depression symptoms. [Meta-Analysis]
findings suggest that a variant near MTNR1A may be associated with job-related exhaustion in shift workers
By integrating genetic and epigenetic data, we identified that a differentially methylated CpG site within the melatonin receptor 1A (MTNR1A) gene mediates the effect of a paternally transmitted genetic variant on the comorbidity of asthma and AR. This study provides a novel insight into the role of epigenetic mechanisms in patients with allergic respiratory diseases.
MT1 (zeige MT1A ELISA Kits) is part of the presynaptic protein network and negatively regulates Cav (zeige CA5A ELISA Kits) 2.2 activity, providing a first hint for potential synaptic functions of MT1 (zeige MT1A ELISA Kits).
rs2119882 polymorphism was associated with polycystic ovary syndrome in Han Chinese. A significant difference in transmission of allele C of rs2119882 was found between obese and non-obese women with PCOS.
results support gene-environment interactions of MTNR1A polymorphisms with smoking and betel quid-chewing habits possibly altering oral-cancer susceptibility and metastasis
Sections from paraffin-embedded normal tissue from 42 individuals, representing the different parts of the GI tract (n=39) and pancreas (n=3) were studied with immunohistochemistry using antibodies for melatonin, MT1 (zeige MT1A ELISA Kits) and MT2 (zeige MT2 ELISA Kits) receptors and serotonin.
There were no significant differences between the expression of MT1 (zeige MT1A ELISA Kits) and histological type, staging, grading, presence of residual disease, or overall survival time.
genetic polymorphisms rs2119882 in melatonin receptor 1A (MTNR1A) and rs10830963 in melatonin receptor 1B (MTNR1B (zeige MTNR1B ELISA Kits)) are associated with an increased risk of developing gestational diabetes mellitus and insulin (zeige INS ELISA Kits) resistance in Han Chinese women
this study provides a detailed delineation of the melatonin-mediated activation of ERK1/2 (zeige MAPK1/3 ELISA Kits) in HEK293 cells that are transfected with melatonin receptor MT1 (zeige MT1A ELISA Kits).
Ecto-5'-nucleotidase (zeige ACPP ELISA Kits) mRNA levels were found to be diminished in both MT1 (zeige MT1 ELISA Kits) and MT1 (zeige MT1 ELISA Kits)/2 knockout mice.
The removal of MT1R or MT2R in mice abolished the daily rhythm in blood glucose levels, but produced small effects on the rhythmic expression patterns of clock genes within skeletal muscle, liver, and adipose tissue.
MT1 (zeige MT1 ELISA Kits) melatonin receptors are involved in neural pathways modulating diurnal rhythms of spontaneous behavior in the homecage as well as pathways regulating depressive and anxiolytic-like behaviors.
These data demonstrate that melatonin MT1 (zeige MT1 ELISA Kits) receptor knockout mice recapitulate several behavioral and neurobiological circadian changes.
The effect of miR (zeige MLXIP ELISA Kits)-29b on endothelial permeability and apoptosis is mediated through the down-regulation of melatonin receptor 1.
there is an an increased proinflammatory status of mice deficient in both membrane-bound melatonin receptors reflected by altered activation of MAPK (zeige MAPK1 ELISA Kits) cascades and transcriptional activation of proinflammatory mediators
This study demonistrated that METH (zeige MTRR ELISA Kits)-induced CPP is dependent on time of day and the presence of the MT1 (zeige MT1 ELISA Kits) receptor, suggesting a role for melatonin in METH (zeige MTRR ELISA Kits)-induced reward.
Heteromeric MT1/MT2 (zeige MT1 ELISA Kits) melatonin receptors modulate photoreceptor function.
These data suggest that melatonin, by acting on MT1 receptors, affects NeuroD expression in the gastrointestinal tract and thus might contribute to circadian regulation in metabolic functions.
MT1R signaling and BMP-4 (zeige BMP4 ELISA Kits) actions are mutually augmented, leading to fine-tuning of ACTH (zeige POMC ELISA Kits) production by corticotrope cells.
The expression of the melatonin receptors MT1 (zeige MT1 ELISA Kits) and MT2 (zeige MT2 ELISA Kits) and the regulatory role of melatonin in the development of bovine Sertoli cells are reported.[MT1 (zeige MT1 ELISA Kits); MT2 (zeige MT2 ELISA Kits)]
The study revealed that ASMT (zeige ASMT ELISA Kits) and MTNR1A genes were expressed in cumulus-oocyte complexes (COCs).
This article presents the first evidence showing expression of mt1A (zeige MT1A ELISA Kits) melatonin receptor in bovine cerebral arteries.
Single nucleotide polymorphism of MTNR1A has no significant effect on litter size traits.
MTNR1A gene has both additive and dominant effects on total number of born piglets and number of piglets born alive.
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
, melatonin receptor type 1A
, melatonin receptor 1A
, Mel1a receptor
, mel1a receptor-like
, melatonin receptor Mel1a Z1.4
, melatonin receptor type 1A z1.4
, melatonin receptor type 1A-like
, mel1a melatonin receptor
, Mel-1a melatonin receptor
, G-protein coupled receptor
, LOW QUALITY PROTEIN: melatonin receptor type 1A
, Mel1a melatonin receptor
, Melatonin receptor type 1A