anti-Meckel Syndrome, Type 1 (MKS1) Antikörper

The protein encoded by MKS1 localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Zusätzlich bieten wir Ihnen MKS1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MKS1 54903 Q9NXB0
MKS1 380718 Q5SW45
MKS1 287612 Q499Q5
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Top anti-MKS1 Antikörper auf antikoerper-online.de

Showing 10 out of 17 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: MKS1 Antibody [NBP2-17303] - Sample (30 ug of whole cell lysate) A: JurKat 10% SDS PAGE gel, diluted at 1:2000. Immunohistochemistry-Paraffin: MKS1 Antibody [NBP2-17303] - Immunohistochemical analysis of paraffin-embedded A549 xenograft, using antibody at 1:100 dilution. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: MKS1 Antibody [NBP1-88691] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 Immunohistochemistry-Paraffin: MKS1 Antibody [NBP1-88691] - Staining of human rectum shows strong cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: MKS1 Antibody [NBP1-88692] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 Immunohistochemistry-Paraffin: MKS1 Antibody [NBP1-88692] - Staining of human colon shows strong cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert IF, WB Western blot analysis of extract of various cells, using MKS1 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$460.63
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: MKS1 Antibody [NLS6809] - Analysis of anti-DUSP22 antibody with human kidney. 0.05 mL Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details
Human Kaninchen Unkonjugiert WB   200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB   100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB   50 μL Anmelden zum Anzeigen 13 bis 16 Tage
$313.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB   100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$420.00
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$157.06
Details

MKS1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human ,


Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-MKS1 Antikörper

  1. Human Polyclonal MKS1 Primary Antibody für IHC, IHC (p) - ABIN4334845 : Mahuzier, Gaudé, Grampa, Anselme, Silbermann, Leroux-Berger, Delacour, Ezan, Montcouquiol, Saunier, Schneider-Maunoury, Vesque: Dishevelled stabilization by the ciliopathy protein Rpgrip1l is essential for planar cell polarity. in The Journal of cell biology 2012 (PubMed)

Weitere Antikörper gegen MKS1 Interaktionspartner

Human Meckel Syndrome, Type 1 (MKS1) Interaktionspartner

  1. we have described a pathogenic variant in the MKS1 resulting in a mild Joubert syndrome phenotype, which broadens the spectrum of mutations in the MKS1.

  2. Dnah11 (zeige DNAH11 Antikörper)(avc)(4) did not disrupt SHF (zeige SHF Antikörper) Hh signaling and caused Atrioventricular septal defects (AVSDs) only concurrently with heterotaxy, a left/right axis abnormality. In contrast, Mks1(avc)(6) disrupted SHF (zeige SHF Antikörper) Hh signaling and caused AVSDs without heterotaxy.We speculate that cilia gene mutations contribute to both syndromic and non-syndromic AVSDs in humans

  3. MKS1 functions in the transition zone at the base of the cilium to regulate ciliary INPP5E content.

  4. describe four patients with mild Joubert phenotypes who carry pathogenic mutations in either MKS1 or B9D1 (zeige B9D1 Antikörper), two genes previously implicated only in Meckel syndrome

  5. identification of a gene, MKS1,(Meckel syndrome) mutated in MKS families linked to 17q.

  6. The Meckel-Gruber Syndrome proteins MKS1 and meckelin (zeige TMEM67 Antikörper) interact and are required for primary cilium formation.

  7. Study concluded that MKS1 and MKS3 (zeige TMEM67 Antikörper) account for the majority of Meckel-Gruber syndrome; polydactyly is usually found in MKS1 but rare in MKS3 (zeige TMEM67 Antikörper); cases with no, or milder, CNS phenotypes were only found in MKS3 (zeige TMEM67 Antikörper).

  8. genotyping of MKS1 & MKS3 (zeige TMEM67 Antikörper) genes in a large, multiethnic cohort of 120 independent cases of Meckel syndrome; first results indicate that the MKS1 & MKS3 (zeige TMEM67 Antikörper) genes are each responsible for about 7% of MKS cases with various mutations in different populations

  9. Our results indicate that MKS1 mutations are not restricted to the Caucasian gene pool and suggest splicing defects are a crucial mutational mechanism in MKS1, and further genetic heterogeneity for MKS.

  10. Mutations in MKS1 is associated with Bardet-Biedl syndrome

Mouse (Murine) Meckel Syndrome, Type 1 (MKS1) Interaktionspartner

  1. demonstrated that the MKS (zeige MKKS Antikörper) transition zone complex cooperates with the BBSome to mediate trafficking of specific trans-membrane receptors to the cilium

  2. Dnah11 (zeige DNAH11 Antikörper)(avc)(4) did not disrupt SHF (zeige SHF Antikörper) Hh signaling and caused Atrioventricular septal defects (AVSDs) only concurrently with heterotaxy, a left/right axis abnormality. In contrast, Mks1(avc)(6) disrupted SHF (zeige SHF Antikörper) Hh signaling and caused AVSDs without heterotaxy.We speculate that cilia gene mutations contribute to both syndromic and non-syndromic AVSDs in humans

  3. Centriole localization of Mks1 is required for ciliogenesis of motile and non-motile cilia, but not for centriole assembly.

  4. Mks1 is required for ciliogenesis and shh (zeige SHH Antikörper) signaling in mouse model of human meckel syndrome.

  5. Mks1 expression in mouse embryos, as determined by in situ hybridization, agrees well with the tissue phenotype of MKS (zeige MKKS Antikörper).

MKS1 Antigen-Profil

Protein Überblick

The protein encoded by this gene localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Mutations in this gene result in Meckel syndrome type 1 and in Bardet-Biedl syndrome type 13. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit MKS1

  • Meckel syndrome, type 1 (MKS1) Antikörper
  • Meckel syndrome, type 1 (Mks1) Antikörper
  • AK190930 Antikörper
  • B8d3 Antikörper
  • BBS13 Antikörper
  • MES Antikörper
  • MKS Antikörper
  • POC12 Antikörper

Bezeichner auf Proteinebene für MKS1

FABB proteome-like protein , Meckel syndrome type 1 protein , POC12 centriolar protein homolog , Meckel syndrome type 1 protein homolog

GENE ID SPEZIES
100056833 Equus caballus
54903 Homo sapiens
380718 Mus musculus
287612 Rattus norvegicus
491110 Canis lupus familiaris
100514538 Sus scrofa
530761 Bos taurus
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