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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Zusätzlich bieten wir Ihnen MMP1 Kits (132) und MMP1 Proteine (44) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 330 products:
Human Polyclonal MMP1 Primary Antibody für WB - ABIN3043405
Man, Gao, Zhang, Liu, Yan, Huang, Liu: Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma. in Cancer biology & therapy 2011
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Cow (Bovine) Polyclonal MMP1 Primary Antibody für IHC, ELISA - ABIN1582229
Yang, Lee, Choi, Lee, Kim, Shin, Han, Kang, Chung: Matrix metalloproteinase-1 induces cleavage of exogenous alphaB-crystallin transduced by a cell-penetrating peptide. in Journal of cellular biochemistry 2011
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Human Polyclonal MMP1 Primary Antibody für ELISA, IHC - ABIN4334917
Huu, Matsushita, Jin, Hamaguchi, Hasegawa, Takehara, Fujimoto: FTY720 ameliorates murine sclerodermatous chronic graft-versus-host disease by promoting expansion of splenic regulatory cells and inhibiting immune cell infiltration into skin. in Arthritis and rheumatism 2013
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Mouse (Murine) Polyclonal MMP1 Primary Antibody für IHC, ELISA - ABIN1586066
Bonta, Matlung, Vos, Peters, Pannekoek, Bakker, de Vries: Nuclear receptor Nur77 inhibits vascular outward remodelling and reduces macrophage accumulation and matrix metalloproteinase levels. in Cardiovascular research 2010
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Mouse (Murine) Polyclonal MMP1 Primary Antibody für IF (p), IHC (p) - ABIN668931
Luo, Zhang, Wang, Hu, Song, Zhang: The inhibitory effect of salmon calcitonin on intervertebral disc degeneration in an ovariectomized rat model. in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2014
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Human Monoclonal MMP1 Primary Antibody für FACS, IF - ABIN966588
Genevay, Finckh, Mezin, Tessitore, Guerne: Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation. in Arthritis research & therapy 2010
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Human Monoclonal MMP1 Primary Antibody für ICC, FACS - ABIN969287
Guan, Shu, Fu, Liu, Xu, Wu: Prevotella intermedia upregulates MMP-1 and MMP-8 expression in human periodontal ligament cells. in FEMS microbiology letters 2009
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Human Polyclonal MMP1 Primary Antibody für IF (p), IHC (p) - ABIN668466
Lu, Cao, Liu, Li, Chen, Fu, Zhang, Liu, Luo, Wang, Li, Caterson: The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage. in Cells, tissues, organs 2012
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Human Polyclonal MMP1 Primary Antibody für IHC (p), IP - ABIN948134
Kim, Xuan, Park: Licoricidin, an isoflavonoid isolated from Glycyrrhiza uralensis Fisher, prevents UVA-induced photoaging of human dermal fibroblasts. in International journal of cosmetic science 2016
Human Polyclonal MMP1 Primary Antibody für WB - ABIN517953
Teng, Wang, Hood, Conrads, Hamilton, Maxwell, Darcy, Conrads: Identification of candidate circulating cisplatin-resistant biomarkers from epithelial ovarian carcinoma cell secretomes. in British journal of cancer 2014
collagen II-activated phosphorylated-DDR2 (zeige DDR2 Antikörper) induces CYR61 (zeige CYR61 Antikörper) through activation of transcription factor activator protein 1 (AP-1 (zeige FOSB Antikörper)). The elevated CYR61 (zeige CYR61 Antikörper), in turn, accelerates MMP1 production via ETS1 (ETS (zeige ETS1 Antikörper) proto-oncogene (zeige RAB1A Antikörper) 1).
M. tuberculosis infection caused enhanced MMP-1, -9, and miR (zeige MLXIP Antikörper)-223 expression, with inhibited BMAL1 (zeige ARNTL Antikörper) expression. MiR (zeige MLXIP Antikörper)-223 modulated BMAL1 (zeige ARNTL Antikörper) expression via the direct binding of BMAL1 (zeige ARNTL Antikörper) 3'-UTR (zeige UTS2R Antikörper).
20(S)-PPD (zeige HPD Antikörper) treatment modulated MMP-1 mRNA expression and the transcriptional activity of activator protein (AP)-1 (zeige FOSB Antikörper), a major transcription factor of MMP-1.
This is the first study to indicate that the genotypes of MMP1 promoter -1607, do not significantly confer susceptibility to lung cancer in a Taiwanese population.
Matrix metalloproteinase-1, -8, -9 and the risk of cardiovascular complications in patients with CHD (zeige CHDH Antikörper) before and after myocardial revascularization.
Results show that the expression level of MMP1 and TIMP1 (zeige TIMP1 Antikörper) is under the regulation of HAS2 (zeige HAS2 Antikörper) leading to migration, invasion and EMT (zeige ITK Antikörper) of oral cancer cells.
DDC (zeige DDC Antikörper) up-regulated MMP-1 in LX-2 cells through the Akt (zeige AKT1 Antikörper) and ERK (zeige EPHB2 Antikörper)/miR (zeige MLXIP Antikörper)-222/ETS-1 (zeige ETS1 Antikörper) pathways.
results suggest that MMP1-1607 1G/2G, MMP3 (zeige MMP3 Antikörper)-1171 5A/6A and MMP9 (zeige MMP9 Antikörper)-1562 C/T gene polymorphisms have synergistic effect on breast cancer. The interactions of MMPs clinical risk factors such as lymph node involvement has shown a strong correlation and might influence the 5-years survival rate, suggesting their potential role in the breast carcinogenesis
The MMP-1 -1607 (2G/1G) and -519 (A/G) polymorphisms may contribute to the onset of osteomyelitis. The 2G/2G genotype carriers had 1.605 times risk of developing osteomyelitis. In addition, frequency of -519GG genotype was obviously higher in case group than that in control group, and GG genotype related to an increased risk of osteomyelitis. Whereas, the -519G allele may be a susceptible factor for osteomyelitis.
No differences in the distribution of the MMP-1 variants were found among Tunisian chronic obstructive pulmonary disease patients and healthy controls. Additionally, no significant association was retrieved between clinicopathologic parameters of chronic obstructive pulmonary disease, MMP-1 levels and this polymorphism.
the identification of MMP1 and MMP10 (zeige MMP10 Antikörper) genes in swine is reported.
increased interstitial MMP1 activity during ischemia and reperfusion is a result of the endothelin protein kinase c (zeige PKC Antikörper) pathway and may be due to enhanced phosphorylation of mmp1
Results indicate that leukemia inhibitory factor (LIF (zeige LIF Antikörper)) and Oncostatin M (zeige OSM Antikörper) increase the expression of MMP-1, MMP-3 (zeige MMP3 Antikörper), and TIMP-1 (zeige TIMP1 Antikörper) several fold, and that their expression is reduced to basal levels in the presence of the LIF (zeige LIF Antikörper) antagonist MH35-BD.
Mmp1 negatively regulates ectopic eye differentiation by restricting the rate of proliferation and the levels of expression of retinal-determining genes dachshund and eyes absent.
Data indicate that matrix metalloproteinases mmp1 and mmp2 (zeige MMP2 Antikörper) mutants have distinct heart phenotypes.
These data demonstrate that Mmp1 modulates PDF processing, which leads to daily structural remodeling and circadian behavior.
A primary function of Mmp1, under the control of the JNK (zeige MAPK8 Antikörper) pathway, is to promote basement membrane repair, which in turn may permit cell migration and the restoration of a continuous tissue.
Drosophila Mmp1 is involved in the regulation of ISC proliferation for maintenance of gut (zeige GUSB Antikörper) homeostasis
Study identified three genes, regeneration (rgn (zeige RGN Antikörper)), augmenter of liver regeneration (alr (zeige GFER Antikörper)) and Matrix metalloproteinase-1 (Mmp1) expressed specifically in blastema cells during disc regeneration.
the phenotype seen in the Hdac4 (zeige HDAC5 Antikörper)(-/-) mice is partially derived from elevation in MMP-13 (zeige MMP13 Antikörper) and may be due to a bone remodeling disorder caused by overexpression of this enzyme.
MEF2C (zeige MEF2C Antikörper) is necessary for Mmp13 (zeige MMP13 Antikörper) gene expression at the transcriptional level and participates in PTH (zeige PTH Antikörper)-stimulated Mmp13 (zeige MMP13 Antikörper) gene expression by increased binding to c-FOS at the AP-1 (zeige JUN Antikörper) site in the Mmp13 (zeige MMP13 Antikörper) promoter.
data reveal a novel involvement of MMP-13 (zeige MMP13 Antikörper) in regulating dendritic cell (DC) immunobiology through moderating MHC-I surface presentation, endocytosis and cytokine/chemokine (zeige CCL1 Antikörper) secretion; furthermore, the reduced MHC-I surface presentation by DCs resulted in a poor CD8 (zeige CD8A Antikörper)(+) T-cell response in vitro; MMP-13 (zeige MMP13 Antikörper) might be a promising target for therapeutic intervention in inflammatory diseases
The progressive process of articular cartilage degeneration was significantly delayed in the knee joints of Ddr2 (zeige DDR2 Antikörper)-deficient mice in comparison to their control littermates. Articular cartilage damage in the knee joints of the mice was associated with increased expression profiles of both Ddr2 (zeige DDR2 Antikörper) and matrix metalloproteinase 13 (zeige MMP13 Antikörper).
Postnatal chondrocyte-specific deletion of Hdac3 (zeige HDAC3 Antikörper) with an inducible Col2a1 (zeige COL2A1 Antikörper)-Cre caused premature production of pErk1/2 and Mmp13 (zeige MMP13 Antikörper) in the growth plate.
Mmp13 (zeige MMP13 Antikörper) is selectively regulated of by 1,25-Dihydroxyvitamin D3, PTH (zeige PTH Antikörper), and Osterix (zeige SP7 Antikörper) through distal enhancers.
Our study contributes to the understanding of the role of HIF1alpha (zeige HIF1A Antikörper) in OA and highlights the HIF1alpha (zeige HIF1A Antikörper)-beta-catenin (zeige CTNNB1 Antikörper) interaction, thus providing new insights into the impact of hypoxia in articular cartilage.
Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1/protease-activated receptor-1 (zeige F2R Antikörper) axis may play a role in neurogenesis following physiological and/or pathological stimuli.
IL-1Ra (zeige IL1RN Antikörper) is associated with MMP-13 (zeige MMP13 Antikörper) expression and has a novel function in such regulation without interference of the IL-1 (zeige IL1A Antikörper) signaling cascade.
We reveal a novel role of AP-2epsilon in the regulation of gene expression in articular chondrocytes, as well as in osteoarthritis development, through modulation of Mmp13 (zeige MMP13 Antikörper) expression and activity.
BoHV-4 infection affects various pathways related to cell proliferation and cell surface integrity, at least three of which were centered on upregulation of matrix metalloproteinase 1 (MMP1). MMP1 transcription was upregulated by the BoHV-4 transactivator IE2/RTA (zeige RBM9 Antikörper), leading to abnormally high metalloproteinase tissue levels, potentially leading to defective endometrium healing and unresolved inflammation.
The expression patterns of MMP1, MMP2 (zeige MMP2 Antikörper), and MMP8 (zeige MMP8 Antikörper) were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1, MMP2 (zeige MMP2 Antikörper), and MMP8 (zeige MMP8 Antikörper) expression levels with meat quality traits were analyzed in cattle. The expression of MMP1, MMP2 (zeige MMP2 Antikörper), and MMP8 (zeige MMP8 Antikörper) were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues.
Data suggest that luteolytic factors (such as interferon gamma (zeige IFNG Antikörper), tumor necrosis factor alpha (zeige TNF Antikörper), and PGF2a) control expression of MMP1, other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.
The results showed that a decrease in MMP-1 and MMP-2 (zeige MMP2 Antikörper) gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts.
Cytoskeletal tension modulates MMP-1 gene expression from tenocytes on micropillar substrates.
MMP-1 promotes VEGFR2 (zeige KDR Antikörper) expression and proliferation of endothelial cells through stimulation of PAR-1 (zeige F2R Antikörper) and activation of NF-kappaB (zeige NFKB1 Antikörper)
These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.
the differential expression and localization of membrane-type 1 matrix metalloproteinase (zeige MMP14 Antikörper) in the corpus luteum suggest that it may have multiple functions throughout the course of the estrous cycle,including activation of pro-MMP-2 (zeige MMP2 Antikörper)
increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 and MMP-13 (zeige MMP13 Antikörper) (follicular apex (zeige APEX1 Antikörper) vs. base) for the preovulatory collagenolysis required for follicle rupture
identification of MT1-MMP (zeige MMP14 Antikörper) in odontoclasts during deciduous tooth resorption might be relevant to the migration activity that these cells have to gain access to the root surface
These results suggest that PEP-1-SIRT2 (zeige SIRT2 Antikörper) promotes matrix metalloproteinases-induced dedifferentiation via ERK (zeige MAPK1 Antikörper) signaling in articular chondrocytes. .
Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 and decreased TIMP-3 (zeige TIMP3 Antikörper) secretion.
ANXA2 (zeige ANXA2 Antikörper) and MMP1 might participate in remodeling during wound healing in the horse.
The polymorphism in the promoter of the MMP-1 gene could be a risk factor for early implant failure of total hip arthroplasty.
These results suggest that MMP-1 and IL-8 (zeige IL8 Antikörper) are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
, interstitial collagenase
, matrix metalloprotease 1
, matrix metalloproteinase 1
, matrix metalloproteinase 1 (type I collagenase)
, matrix metalloproteinase-1
, collagenase 3
, matrix metalloproteinase 13
, matrix metalloproteinase-13
, matrix metalloproteinase-18
, matrix metallopeptidase 1a
, matrix metalloproteinase 1a (interstitial collagenase)
, myocardial collagenase