anti-Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,6-N-Acetyl-Glucosaminyltransferase (MGAT5) Antikörper

The protein encoded by MGAT5 belongs to the glycosyltransferase family. Zusätzlich bieten wir Ihnen MGAT5 Kits (15) und MGAT5 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MGAT5 107895 Q8R4G6
MGAT5 4249 Q09328
MGAT5 65271 Q08834
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Top anti-MGAT5 Antikörper auf

Showing 10 out of 49 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (36.89 KDa) . 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
Human Kaninchen Unkonjugiert FACS, WB MGAT5 Antibody (C-term) (ABIN657736) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the MGAT5 antibody detected the MGAT5 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Maus Unkonjugiert IHC (p), ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: N-Acetylglucosaminyltransferase V/MGAT5 Antibody [NBP1-83354] - Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cell lines, using MGAT5 antibody. 100 μL Anmelden zum Anzeigen 16 Days
Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen Cy7 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen HRP IHC (p), WB   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage

MGAT5 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-MGAT5 Antikörper

  1. Human Polyclonal MGAT5 Primary Antibody für ELISA, WB - ABIN561815 : Hamanoue, Ikeda, Ogata, Takamatsu: Predominant expression of N-acetylglucosaminyltransferase V (GnT-V) in neural stem/progenitor cells. in Stem cell research 2015 (PubMed)

Weitere Antikörper gegen MGAT5 Interaktionspartner

Mouse (Murine) Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,6-N-Acetyl-Glucosaminyltransferase (MGAT5) Interaktionspartner

  1. Overexpression of GnT-V exacerbated murine experimental colitis by inducing macrophage dysfunction, thereby enhancing colorectal tumorigenesis

  2. Expression of GnT-V was also elevated in bleomycin (BLM)-injected sclerotic skin, and MGAT5(-/-) mice were resistant to BLM-induced skin sclerosis with reduced collagen type 1 alpha1 content.

  3. GnT-V regulates the canonical Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling pathway by modulating N-glycosylation of Wnt (zeige WNT2 Antikörper) receptors, which changes cancer stem cells in colorectal tumors, causing altered colon tumorigenesis and adenoma progression in Apc (zeige APC Antikörper)(min/+) mice

  4. this study suggests that the GnT-V expression is inversely correlated with radiation sensitivity in prostate cancer(PCa (zeige ENPP1 Antikörper))cells

  5. The GnT-V prevented steatohepatitis progression through modulating lymphocyte and HSC (zeige FUT1 Antikörper) functions.

  6. GnT-V overexpression promotes EMT (zeige ITK Antikörper) and keratinocyte migration in part through enhanced EGF receptor (zeige EGFR Antikörper) signaling.

  7. Mgat5-dependent glycosylation of proteins can modulate acquired immune responses, but it is not essential for the development of OVA-induced eosinophilic airway inflammation.

  8. GnT-V expression and its branched glycan products effectively modulate her-2 (zeige ERBB2 Antikörper)-mediated signaling pathways that, in turn, regulate the relative proportion of tumor initiating cells and the latency of her-2 (zeige ERBB2 Antikörper)-driven tumor onset

  9. A secreted type of beta 1,6-N-acetylglucosaminyltransferase V (zeige MGAT5B Antikörper) (GnT-V) induces tumor angiogenesis without mediation of glycosylation: a novel function of GnT-V distinct from the original glycosyltransferase (zeige GTDC2 Antikörper) activity.

  10. expression of Mgat5 sensitized cells to multiple cytokines;Galectin-3 (zeige LGALS3 Antikörper) cross-linked Mgat5-modified N-glycans on epidermal growth factor (zeige EGF Antikörper) and transforming growth factor-beta receptors at the cell surface and delayed their removal by constitutive endocytosis

Human Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,6-N-Acetyl-Glucosaminyltransferase (MGAT5) Interaktionspartner

  1. Our data suggest that oxidative stress induces the overexpression of MGAT5 via the regulation of the focal adhesion kinase-extracellular signal-regulated kinase signaling pathway, which, in turn, affects the function of endothelial cells, which then participates in the pathogenesis of preeclampsia.

  2. PTPalpha (zeige PTPRA Antikörper) is identified as a novel substrate of N-Acetylglucosaminyltransferase V (GnT-V) and could be a factor regulating promotion of migration in breast cancer cells

  3. Tunicamycin, an inhibitor of N-glycan biosynthesis, was also able to enhance the radiosensitivity of U251 cells. Thus, our results suggest that development of therapeutic approaches targeting N-linked beta1,6-GlcNAc branches which are encoded by N-acetylglucosaminyltransferase V may be a promising strategy in glioblastoma treatment

  4. the knockdown of GnTV significantly suppressed the proliferation, migration and invasion (P<0.05) of the SMMC7721/R cells.

  5. role in the inhibition of trophoblast cell invasion and migration during early pregnancy by direct or indirect regulation of MMP2 (zeige MMP2 Antikörper)/9 activity

  6. the level of TGFBR1 and early osteogenic differentiation were abolished in the DPSCs transfected with siRNA for GnT-V knockdown...GnT-V plays a critical role in the hexosamine-induced activation of TGF-b signaling and osteogenic differentiation

  7. binding of recombinant Gal-3 (zeige LGALS3 Antikörper) to the RPE (zeige RPE Antikörper) cell surface and inhibitory effects on RPE (zeige RPE Antikörper) attachment and spreading largely dependent on interaction with Mgat5 modified N-glycans

  8. Mgat5 plays an important role in early spontaneous miscarriage in humans.

  9. Gnt-V caused tumour growth more quickly

  10. High expression of GnT-V was observed in infiltrating cells in skin section samples from systemic and localized patients with scleroderma.

MGAT5 Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies.

Genbezeichner und Symbole assoziert mit MGAT5

  • mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase (Mgat5) Antikörper
  • mannoside acetylglucosaminyltransferase 5 (Mgat5) Antikörper
  • mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase (MGAT5) Antikörper
  • 4930471A21Rik Antikörper
  • 5330407H02Rik Antikörper
  • AI480971 Antikörper
  • GlcNAc-TV Antikörper
  • GNT-V Antikörper
  • GNT-VA Antikörper
  • MGAT5 Antikörper

Bezeichner auf Proteinebene für MGAT5

Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A , Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase , GlcNAc-T V , Mannoside acetylglucosaminyltransferase 5 , GNT-V , N-acetylglucosaminyl-transferase V , alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A , alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase , beta1,6N-acetylglucosaminyltransferase V , glcNAc-T V , mannoside acetylglucosaminyltransferase 5 , N-acetylglucosaminyltransferase V , alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase

100760162 Cricetulus griseus
107895 Mus musculus
4249 Homo sapiens
65271 Rattus norvegicus
101107672 Ovis aries
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