anti-Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1) Antikörper

MAN2B1 encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Zusätzlich bieten wir Ihnen Mannosidase, Alpha, Class 2B, Member 1 Proteine (10) und Mannosidase, Alpha, Class 2B, Member 1 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MAN2B1 17159 O09159
Anti-Ratte MAN2B1 MAN2B1 361378  
MAN2B1 4125 O00754
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Top anti-Mannosidase, Alpha, Class 2B, Member 1 Antikörper auf antikoerper-online.de

Showing 10 out of 11 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Maus Kaninchen Unkonjugiert WB Western blot analysis of extracts of mouse liver cells, using MAN2B1 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$323.13
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: MAN2B1 Antibody [NBP1-81326] - Staining of human small intestine shows strong granular cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert WB Western Blot analysis of MAN2B1 expression in transfected 293T cell line by MAN2B1 MaxPab polyclonal antibody.<br><br>Lane 1: MAN2B1 transfected lysate(113.70 KDa).<br>Lane 2: Non-transfected lysate.<br> MAN2B1 MaxPab rabbit polyclonal antibody. Western Blot analysis of MAN2B1 expression in HepG2. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$418.57
Details
Human Maus Unkonjugiert WB Western Blot analysis of MAN2B1 expression in transfected 293T cell line by MAN2B1 MaxPab polyclonal antibody.<br><br>Lane 1: MAN2B1 transfected lysate(111.21 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μg Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details
Human Maus Unkonjugiert WB   50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$837.83
Details
Human Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$903.83
Details
Human Kaninchen Unkonjugiert ICC, IHC, IP, WB   100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$350.00
Details
Human Maus Unkonjugiert WB   50 μg Anmelden zum Anzeigen 11 bis 16 Tage
$625.43
Details
Human Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$666.29
Details
Human Kaninchen Unkonjugiert ELISA, IF/ICC, IHC, WB   100 μg Anmelden zum Anzeigen 71 Days
$536.25
Details

MAN2B1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Mouse (Murine)


Human ,
,

Weitere Antikörper gegen Mannosidase, Alpha, Class 2B, Member 1 Interaktionspartner

Mouse (Murine) Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1) Interaktionspartner

  1. Mannose receptor (-/-) liver sinusoidal endothelial cells had markedly and significantly reduced enzyme activities for four out of five lysosomal enzymes tested, i.e., cathepsin-D, alpha-mannosidase, beta-hexosaminidase and arylsulfatase.

Human Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1) Interaktionspartner

  1. A novel heterozygous mutation (c.2013G>A; p.R638H) of MANBA (zeige MANBA Antikörper) was identified in patients with autosomal-dominant nystagmus. An additional mutation (c.2346T>A; p.L749H) in MANBA (zeige MANBA Antikörper) was found by screening patients with sporadic nystagmus.

  2. Our results indicate a correlation between the MAN2B1 genotypes and the cognitive function, upper limb coordination, balance, FVC% and the storage of oligosaccharides in CSF (zeige CSF2 Antikörper).

  3. The results showed that the alpha-mannosidosis patient has compound heterozygous mutations in the MAN2B1 gene

  4. MAN2B1 is targeted to the vacuole without passing through the Golgi complex.

  5. Expressed MAN2B1 and MAN2B2 (zeige MAN2B2 Antikörper) in Drosophila S2 cells and functionally characterized them. MAN2B1 and MAN2B2 (zeige MAN2B2 Antikörper) were significantly inhibited by the class II alpha-mannosidase inhibitors, swainsonine and mannostatin A.

  6. 5 new mutations were found in the MAN2B1 gene: c.157G>T, c.562C>T, c.599A>T, c.293dupA, c.2402G>A (p.E53X, p.R188X, p.H200L, p.Y99VfsX61, p.G801D). p.H200L could involve the catalytic mechanism. p.G801D would affect correct folding.

Cow (Bovine) Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1) Interaktionspartner

Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1) Antigen-Profil

Protein Überblick

This gene encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First, a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). Next, the 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit MAN2B1

  • mannosidase alpha class 2B member 1 (MAN2B1) Antikörper
  • mannosidase, alpha, class 2B, member 1 (man2b1) Antikörper
  • mannosidase 2, alpha B1 (Man2b1) Antikörper
  • mannosidase alpha class 2B member 1 (Man2b1) Antikörper
  • mannosidase, alpha, class 2B, member 1 (Man2b1) Antikörper
  • AW107687 Antikörper
  • Laman Antikörper
  • MANB Antikörper

Bezeichner auf Proteinebene für MAN2B1

mannosidase, alpha, class 2B, member 1 , lysosomal alpha-mannosidase (109.3 kD) (XF355) , lysosomal alpha-mannosidase , lysosomal alpha-mannosidase-like , lysosomal acid alpha-mannosidase , mannosidase alpha class 2B member 1 , mannosidase alpha-B , mannosidase 2, alpha B1 , mannosidase, alpha B, lysosomal , laman

GENE ID SPEZIES
484932 Canis lupus familiaris
779924 Xenopus (Silurana) tropicalis
100010377 Monodelphis domestica
100174476 Pongo abelii
100395073 Callithrix jacchus
100598622 Nomascus leucogenys
17159 Mus musculus
100718205 Cavia porcellus
361378 Rattus norvegicus
4125 Homo sapiens
282272 Bos taurus
493697 Felis catus
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